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1.
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14 p, 1.6 MB |
Circulating virome and inflammatory proteome in patients with ST-elevation myocardial infarction and primary ventricular fibrillation
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Oliveras, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revuelta-López, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Garcia Garcia, Cosme (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cserkóová, Adriana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rueda, Ferran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Labata, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ferrer Vinardel, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Montero, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
El-Ouaddi, Nabil (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez, Maria José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Primary ventricular fibrillation (PVF) is a life-threatening complication of ST-segment elevation myocardial infarction (STEMI). It is unclear what roles viral infection and/or systemic inflammation may play as underlying triggers of PVF, as a second hit in the context of acute ischaemia. [...]
2022 -  10.1038/s41598-022-12075-x
Scientific reports, Vol. 12, Num 1 (may 2022)
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2.
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19 p, 5.8 MB |
Deep Learning Analyses to Delineate the Molecular Remodeling Process after Myocardial Infarction
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Iborra Egea, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rudilla, F (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Soler-Botija, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revuelta-López, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ferrer-Curriu, Gemma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Segú-Vergés, Cristina (Anaxomics Biotech S.L.) ;
Mellado-Bergillos, Araceli (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gomez-Puchades, Pol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gastelurrutia, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Specific proteins and processes have been identified in post-myocardial infarction (MI) pathological remodeling, but a comprehensive understanding of the complete molecular evolution is lacking. We generated microarray data from swine heart biopsies at baseline and 6, 30, and 45 days after infarction to feed machine-learning algorithms. [...]
2021 - 10.3390/cells10123268
Cells, Vol. 10 (november 2021)
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3.
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15 p, 4.3 MB |
Acellular cardiac scaffolds enriched with MSC-derived extracellular vesicles limit ventricular remodelling and exert local and systemic immunomodulation in a myocardial infarction porcine model
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Monguió-Tortajada, Marta (Institut Germans Trias i Pujol) ;
Prat-Vidal, Cristina (Banc de Sang i Teixits) ;
Martínez-Falguera, Daina (Universitat de Barcelona) ;
Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Soler-Botija, Carolina (Instituto de Salud Carlos III) ;
Courageux, Yvan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Munizaga-Larroudé, Micaela (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morón-Font, Miriam (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Borràs i Serres, Francesc Enric (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ;
Rudilla, F. (Institut d'Investigació Biomèdica de Bellvitge) ;
Gálvez-Montón, Carolina (Institut d'Investigació Biomèdica de Bellvitge)
Rationale: Extracellular vesicles (EVs) from mesenchymal stromal cell (MSC) are a potential therapy for cardiac healing after myocardial infarction (MI). Nevertheless, neither their efficient administration nor therapeutic mechanisms are fully elucidated. [...]
2022 - 10.7150/thno.72289
Theranostics, Vol. 12, Issue 10 (June 2022) , p. 4656-4670
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4.
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13 p, 3.5 MB |
Electrophysiological effects of adipose graft transposition procedure (AGTP) on the post-myocardial infarction scar : A multimodal characterization of arrhythmogenic substrate
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Adeliño, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Falguera, Daina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Curiel, Carolina (Boston Scientific Department. Barcelona Delegation) ;
Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marsal, Roger (Boston Scientific Department. Barcelona Delegation) ;
Rodríguez-Leor, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fadeuilhe, Edgar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Aranyó, Júlia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revuelta-López, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sarrias, Axel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bazán, Víctor (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Andrés-Cordón, Joan Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villuendas-Sabaté, Roger (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bisbal, Felipe (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
To assess the arrhythmic safety profile of the adipose graft transposition procedure (AGTP) and its electrophysiological effects on post-myocardial infarction (MI) scar. Myocardial repair is a promising treatment for patients with MI. [...]
2022 - 10.3389/fcvm.2022.983001
Frontiers in Cardiovascular Medicine, Vol. 9 (september 2022)
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5.
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15 p, 3.5 MB |
Treatment of cardiac fibrosis : from neuro-hormonal inhibitors to CAR-T cell therapy
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Morfino, Paolo (Scuola Superiore Sant'Anna) ;
Aimo, Alberto (Fondazione Toscana Gabriele Monasterio) ;
Castiglione, Vincenzo (Scuola Superiore Sant'Anna) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Emdin, Michele (Fondazione Toscana Gabriele Monasterio) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Cardiac fibrosis is characterized by the deposition of extracellular matrix proteins in the spaces between cardiomyocytes following both acute and chronic tissue damage events, resulting in the remodeling and stiffening of heart tissue. [...]
2022 - 10.1007/s10741-022-10279-x
Heart Failure Reviews, october 2022, p. 1-15
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6.
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7 p, 1.6 MB |
Neoinnervation and neovascularization of acellular pericardial-derived scaffolds in myocardial infarcts
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Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernandez-Figueras, M. Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martí, Mercè (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ;
Soler-Botija, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perea-Gil, Isaac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Llucià-Valldeperas, Aida (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Engineered bioimplants for cardiac repair require functional vascularization and innervation for proper integration with the surrounding myocardium. The aim of this work was to study nerve sprouting and neovascularization in an acellular pericardial-derived scaffold used as a myocardial bioimplant. [...]
2015 - 10.1186/s13287-015-0101-6
Stem cell research & therapy, Vol. 6 (may 2015)
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7.
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8.
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11 p, 682.2 KB |
Mesenchymal stem cells for cardiac repair : are the actors ready for the clinical scenario?
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Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mirabel, Clémentine (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vives Armengol, Joaquim (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
For years, sufficient progress has been made in treating heart failure following myocardial infarction; however, the social and economic burdens and the costs to world health systems remain high. Moreover, treatment advances have not resolved the underlying problem of functional heart tissue loss. [...]
2017 - 10.1186/s13287-017-0695-y
Stem cell research & therapy, Vol. 8 (october 2017)
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9.
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7 p, 1.6 MB |
Rationale and design of a multicentre, prospective, randomised, controlled clinical trial to evaluate the efficacy of the adipose graft transposition procedure in patients with a myocardial scar : the AGTP II trial
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Gastelurrutia, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cámara, Maria-Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bustamante-Munguira, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-Pavía, Pablo (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Avanzas, Pablo (Hospital Universitario Central de Asturias) ;
Alberto San Román, J. (Hospital Clínico Universitario de Valladolid) ;
Pascual-Figal, Domingo (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
De Teresa, Eduardo (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Crespo-Leiro, Maria Generosa (Complejo Hospitalario Universitario de A Coruña) ;
Manito, Nicolás (Hospital Universitari de Bellvitge) ;
Núñez, Julio (Hospital Clínic Universitari (València)) ;
Fernández Avilés, F (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Caballero, Ángel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Brugada, Ramon (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martín, Carlos (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Silva, Jacobo (Hospital Universitario Central de Asturias) ;
Revilla-Orodea, Ana (Hospital Clínico Universitario de Valladolid) ;
Cánovas López, Sergio Juan (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Melero, Jose M. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Cuenca-Castillo, Jose J. (Complejo Hospitalario Universitario de A Coruña) ;
Gonzalez-Pinto, Angel (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac adipose tissue is a source of progenitor cells with regenerative capacity. Studies in rodents demonstrated that the intramyocardial delivery of cells derived from this tissue improves cardiac function after myocardial infarction (MI). [...]
2017 - 10.1136/bmjopen-2017-017187
BMJ open, Vol. 7 (august 2017)
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10.
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8 p, 1.6 MB |
Ex vivo assessment and in vivo validation of non-invasive stent monitoring techniques based on microwave spectrometry
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Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ;
Arauz-Garofalo, Gianluca (Universitat de Barcelona. Departament de Física de la Matèria Condensada) ;
Rodriguez-Leor, Oriol (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Soler-Botija, Carolina (Institut Germans Trias i Pujol) ;
Amorós García de Valdecasas, Susana (Universitat Politècnica de Catalunya. CommSensLab) ;
Gerez-Britos, Flavio David (Universitat de Barcelona. Departament de Física de la Matèria Condensada) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
O'Callaghan, Juan Manuel (Universitat Politècnica de Catalunya. CommSensLab) ;
Macià, Ferran (Universitat de Barcelona. Departament de Física de la Matèria Condensada) ;
Tejada, Javier (Universitat de Barcelona. Departament de Física de la Matèria Condensada)
Some conditions are well known to be directly associated with stent failure, including in-stent re-occlusion and stent fracture. Currently, identification of these high-risk conditions requires invasive and complex procedures. [...]
2018 - 10.1038/s41598-018-33254-9
Scientific reports, Vol. 8 (october 2018)
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