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9 p, 1.3 MB |
Lymphangioleiomyomatosis : Searching for potential biomarkers
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Revilla-López, Eva (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ruiz de Miguel, Victoria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Berastegui García, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Boada-Pérez, Meritxell (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mendoza-Valderrey, Alberto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arjona-Peris, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zapata-Ortega, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Monforte, Víctor (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Bravo Masgoret, Carles (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Roman, Antonio (Instituto de Salud Carlos III) ;
Gómez-Ollés, Susana (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Sáez-Giménez, Berta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Vascular endothelial growth factor-D (VEGF-D) is the most commonly used biomarker for diagnosing lymphangioleiomyomatosis (LAM). However, lung biopsy is often necessary as well; therefore, defining new biomarkers for LAM is crucial. [...]
2023 -  10.3389/fmed.2023.1079317
Frontiers in Medicine, Vol. 10 (february 2023)
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9 p, 1.2 MB |
Long-term results of sirolimus treatment in lymphangioleiomyomatosis : a single referral centre experience
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Revilla-López, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Berastegui García, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Méndez, Alejandra (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sáez-Giménez, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz de Miguel, Victoria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Monforte, Víctor (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Bravo Masgoret, Carles (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Pujana, Miguel Angel (Institut d'Investigació Biomèdica de Bellvitge) ;
Ramon, Maria Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gómez-Ollés, Susana (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Roman, Antonio (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Universitat Autònoma de Barcelona
There are few published data on long-term treatment with sirolimus in lymphangioleiomyomatosis (LAM). The objective of this study was to describe the long-term effect of sirolimus in a series of LAM patients followed up in a referral centre, focusing on pulmonary function. [...]
2021 - 10.1038/s41598-021-89562-0
Scientific reports, Vol. 11 (may 2021)
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3.
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9 p, 849.0 KB |
Sputum Inflammatory Profile Before and After Specific Inhalation Challenge in Individuals with Suspected Occupational Asthma
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Sánchez-Vidaurre, Sara (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Gómez-Ollés, Susana (Hospital Universitari Vall d'Hebron) ;
Morell Brotad, Ferran 1944- (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The aim of this study was to establish the sputum inflammatory profile and changes in levels of leukotriene B (LTB) and a panel of Th1/Th2 cytokines in subjects with suspected occupational asthma (OA) following specific inhalation challenge (SIC) to high-molecular-weight (HMW) and low-molecular-weight (LMW) agents. [...]
2013 - 10.1371/journal.pone.0078304
PloS one, Vol. 8, Issue 11 (November 2013) , art. e78304
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7 p, 542.7 KB |
Persistence of Asthmatic Response after Ammonium Persulfate-Induced Occupational Asthma in Mice
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Ollé-Monge, Marta (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Vanoirbeek, Jeroen A. J. (Centre for Environment and Health, KU Leuven, Belgium) ;
Gómez-Ollés, Susana (Hospital Universitari Vall d'Hebron) ;
Morell Brotad, Ferran 1944- (Hospital Universitari Vall d'Hebron) ;
Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron)
Since persulfate salts are an important cause of occupational asthma (OA), we aimed to study the persistence of respiratory symptoms after a single exposure to ammonium persulfate (AP) in AP-sensitized mice. [...]
2014 - 10.1371/journal.pone.0109000
PloS one, Vol. 9 (october 2014)
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5.
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7 p, 799.9 KB |
A Rapid Test for Soy Aeroallergens Exposure Assessment
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Álvarez-Simón, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Cruz Carmona, María Jesús (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Untoria, María-Dolores (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Villalbí, Joan Ramón (Institut d'Investigació Biomèdica Sant Pau) ;
Morell Brotad, Ferran 1944- (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Gómez-Ollés, Susana (Universitat Autònoma de Barcelona. Departament de Medicina)
Determining soy aeroallergens levels is extremely important in the assessment of health risks due to these airborne substances. Currently, soy aeroallergens exposure in the environment is monitored using enzyme immunoassays (EIA) which must be evaluated in a specialized laboratory by skilled personnel. [...]
2014 - 10.1371/journal.pone.0088676
PloS one, Vol. 9, Issue 2 (February 2014) , art. e88676
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6.
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14 p, 6.3 MB |
Effects of diesel exhaust particle exposure on a murine model of asthma due to soybean
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Álvarez-Simón, Daniel (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Gómez-Ollés, Susana (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
de Homdedeu, Miquel (Hospital Universitari Vall d'Hebron) ;
Untoria, María-Dolores (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Cruz Carmona, María Jesús (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Exposure to soybean allergens has been linked to asthma outbreaks. Exposure to diesel exhaust particles (DEP) has been associated with an increase in the risk of asthma and asthma exacerbation; however, in both cases the underlying mechanisms remain poorly understood, as does the possible interaction between the two entities. [...]
2017 - 10.1371/journal.pone.0179569
PloS one, Vol. 12 (june 2017)
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14 p, 1.1 MB |
Use of serum KL-6 level for detecting patients with restrictive allograft syndrome after lung transplantation
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Berastegui García, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gómez-Ollés, Susana (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Mendoza-Valderrey, Alberto (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pereira-Veiga, Thais (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Culebras Amigo, Mario (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Monforte, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sáez-Giménez, Berta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sintes-Permanyer, Helena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz de Miguel, Victoria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bravo Masgoret, Carles (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sacanell, Judith (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramon, María-Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Romero, Laura (Hospital Universitari Vall d'Hebron) ;
Deu, Maria (Hospital Universitari Vall d'Hebron) ;
Román, Antonio (Román Broto) (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
KL-6 is an antigen produced mainly by damaged type II pneumocytes that is involved in interstitial lung disease. Chronic lung allograft dysfunction (CLAD) after lung transplantation (LT) is a major concern for LT clinicians, especially in patients with restrictive allograft syndrome (RAS). [...]
2020 - 10.1371/journal.pone.0226488
PloS one, Vol. 15 (january 2020)
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9 p, 776.9 KB |
Near-normal aerobic capacity in long-term survivors after lung transplantation
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Sáez-Giménez, Berta (Hospital Universitari Vall d'Hebron) ;
Barrecheguren, Miriam (Hospital Universitari Vall d'Hebron) ;
Ramon, Maria Antònia (Hospital Universitari Vall d'Hebron) ;
Gomez-Garrido, Alba (Hospital Universitari Vall d'Hebron) ;
Bravo Masgoret, Carles (Hospital Universitari Vall d'Hebron) ;
Monforte, Víctor (Hospital Universitari Vall d'Hebron) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Berastegui García, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Revilla-López, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Romero, Christian (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Laporta, Rosalía (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Fernández-Rozas, Sonia (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Redel-Montero, Javier (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Solé, Amparo (Hospital Universitari i Politècnic La Fe (València)) ;
de la Torre, Mercedes (Complejo Hospitalario Universitario de A Coruña) ;
Puente, Luis (Hospital General Universitario Gregorio Marañón) ;
Roman, Antonio (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Gómez-Ollés, Susana (Hospital Universitari Vall d'Hebron) ;
Ojanguren, Iñigo (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
The aim of this study was to elucidate whether long-term LT survivors with normal spirometry achieve normal exercise capacity, and to identify predictive factors of exercise capacity. This was a cross-sectional multicentre study, where bilateral LT recipients who survived at least 10 years after LT, with normal spirometry, no diagnosis of CLAD and modified Medical Research Council dyspnoea degree ≤2 underwent cardiopulmonary exercise testing (CPET). [...]
2021 - 10.1183/23120541.00381-2020
ERJ Open Research, Vol. 7 (february 2021)
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9.
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8 p, 1.2 MB |
A rapid test for the environmental detection of pigeon antigen
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Sánchez-Díez, Silvia (Hospital Universitari Vall d'Hebron) ;
Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Álvarez-Simón, Daniel (Hospital Universitari Vall d'Hebron) ;
Montalvo Porro, Tomas (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Hoet, Peter M. (Department of Public Health and Primary Care, Centre for Environment and Health, Leuven) ;
Vanoirbeek, Jeroen A. (Department of Public Health and Primary Care, Centre for Environment and Health, Leuven) ;
Gómez-Ollés, Susana (Hospital Universitari Vall d'Hebron)
Avoidance of inhaled bird antigens is essential to prevent hypersensitivity pneumonitis disease progression. The aim of the present study was to develop a sandwich enzyme link immunoassay (ELISA) and an immunochromatographic test (ICT) and compare their ability to detect pigeon antigens in environmental samples. [...]
2021 - 10.1016/j.scitotenv.2021.147789
Science of the total environment, Vol. 788 (september 2021)
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7 p, 1.1 MB |
Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma
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Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron) ;
Ollé Monge, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Vanoirbeek, J. A. (Centre of Environment and Health, KU Leuven) ;
Assialioui, Abdelilah (Hospital Universitari Vall d'Hebron) ;
Gómez Ollés, Susana (Hospital Universitari Vall d'Hebron) ;
Muñoz Gall, Xavier (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after dermal sensitization in a mouse model. [...]
2016 - 10.1186/s13223-016-0131-3
Allergy, asthma, and clinical immunology, Vol. 12 (May 2016) , art. 26
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