Home > Search Results: García de Coca, Alfonso
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13 p, 1.8 MB Integrated Genomic Analysis of Chromosomal Alterations and Mutations in B-Cell Acute Lymphoblastic Leukemia Reveals Distinct Genetic Profiles at Relapse / Forero-Castro, Maribel (Universidad Pedagógica y Tecnológica de Colombia) ; Montaño, Adrián (Universidad de Salamanca) ; Robledo, Cristina (Universidad de Salamanca) ; García de Coca, Alfonso (Hospital Clínico Universitario de Valladolid) ; Fuster, José Luis (Hospital Universitario Virgen de la Arrixaca (Múrcia)) ; De las Heras, Natalia (Hospital Virgen Blanca (León)) ; Queizán, José Antonio (Hospital General de Segovia) ; Hernández-Sánchez, María (Universidad de Salamanca) ; Corchete Sánchez, Luis Antonio (Hospital Universitario de Salamanca) ; Martín-Izquierdo, Marta (Universidad de Salamanca) ; Ribera Salas, Jordi (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ribera, Jose-Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Benito, Rocío (Universidad de Salamanca) ; Hernández Rivas, Jesús María (Hospital Universitario de Salamanca)
The clonal basis of relapse in B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is complex and not fully understood. Next-generation sequencing (NGS), array comparative genomic hybridization (aCGH), and multiplex ligation-dependent probe amplification (MLPA) were carried out in matched diagnosis-relapse samples from 13 BCP-ALL patients to identify patterns of genetic evolution that could account for the phenotypic changes associated with disease relapse. [...]
2020 - 10.3390/diagnostics10070455
Diagnostics, Vol. 10 (july 2020)  
Detailed record - Creative Commons

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