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19 p, 13.2 MB Angiotensin Type 1 Receptor Antagonists Protect Against Alpha-Synuclein-Induced Neuroinflammation and Dopaminergic Neuron Death / Rodriguez-Perez, Ana I. (Networking Research Center on Neurodegenerative Diseases (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Madrid, 28031 Spain) ; Sucunza, Diego (University of Navarra. Neurosciences Division, Centro de Investigación Médica Aplicada) ; Pedrosa, Maria A. (Networking Research Center on Neurodegenerative Diseases (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Madrid, 28031 Spain) ; Garrido-Gil, Pablo (Networking Research Center on Neurodegenerative Diseases (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Madrid, 28031 Spain) ; Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ; Lanciego, Jose L. (University of Navarra. Neurosciences Division, Centro de Investigación Médica Aplicada) ; Labandeira-Garcia, Jose L. (Networking Research Center on Neurodegenerative Diseases (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Madrid, 28031 Spain) ; Universitat Autònoma de Barcelona
The loss of dopaminergic neurons and α-synuclein accumulation are major hallmarks of Parkinson's disease (PD), and it has been suggested that a major mechanism of α-synuclein toxicity is microglial activation. [...]
2018 - 10.1007/s13311-018-0646-z
Neurotherapeutics, Vol. 15 (july 2018) , p. 1063-1081  

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