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11 p, 958.8 KB |
Effects of Mediterranean diet or mindfulness-based stress reduction on fetal and neonatal brain development : a secondary analysis of a randomized clinical trial
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Nakaki, Ayako (Hospital Clínic i Provincial de Barcelona) ;
Crovetto, Francesca (Hospital Clínic i Provincial de Barcelona) ;
Urru, Andrea (Universitat Pompeu Fabra) ;
Piella, Gemma (Universitat Pompeu Fabra) ;
Borras, Roger (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ;
Comte, Valentin (Universitat Pompeu Fabra) ;
Vellvé, Kilian (Hospital Clínic i Provincial de Barcelona) ;
Paules, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Segalés, Laura (Hospital Clínic i Provincial de Barcelona) ;
Dacal, Marta (Hospital Clínic i Provincial de Barcelona) ;
Gomez, Yvan (Hospital Clínic i Provincial de Barcelona) ;
Youssef, Lina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Casas, Rosa (Hospital Clínic i Provincial de Barcelona) ;
Castro-Barquero, Sara (Hospital Clínic i Provincial de Barcelona) ;
Martín-Asuero, Andrés (Instituto esMindfulness, Barcelona) ;
Oller Guzmán, Teresa (Instituto esMindfulness, Barcelona) ;
Morilla, I. (Hospital Clínic i Provincial de Barcelona) ;
Martínez-Àran, Anabel (Hospital Clínic i Provincial de Barcelona) ;
Camacho, Alba (Hospital Clínic i Provincial de Barcelona) ;
Pascual Tutusaus, Mireia (Hospital Clínic i Provincial de Barcelona) ;
Arranz, Angela (Hospital Clínic i Provincial de Barcelona) ;
Rebollo-Polo, Monica (Institut de Recerca Sant Joan de Dèu) ;
Gomez-Chiari, Marta (Hospital Sant Joan de Déu (Manresa)) ;
Bargalló, Núria (Hospital Clínic i Provincial de Barcelona) ;
Pozo, Óscar J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gomez-Gomez, A (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Izquierdo Renau, Montserrat (Universitat de Barcelona) ;
Eixarch, Elisenda (Hospital Clínic i Provincial de Barcelona) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Estruch, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Crispi, Fatima (Hospital Clínic i Provincial de Barcelona) ;
Gonzalez-Ballester, Miguel Angel (Universitat Pompeu Fabra) ;
Gratacós, Eduard (Hospital Clínic i Provincial de Barcelona)
BACKGROUND: Maternal suboptimal nutrition and high stress levels are associated with adverse fetal and infant neurodevelopment. OBJECTIVE: This study aimed to investigate if structured lifestyle interventions involving a Mediterranean diet or mindfulness-based stress reduction during pregnancy are associated with differences in fetal and neonatal brain development. [...]
2023 -  10.1016/j.ajogmf.2023.101188
American journal of obstetrics & gynecology, maternal-fetal medicine, Vol. 5 Núm. 12 (december 2023)
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11 p, 308.4 KB |
Association between ultra-processed food consumption and gut microbiota in senior subjects with overweight/obesity and metabolic syndrome
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Atzeni, Alessandro (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Martínez, María Ágeles (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Babio, Nancy (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Konstanti, Prokopis (Wageningen University) ;
Tinahones, Francisco J.. (Hospital Universitario Virgen de la Vic) ;
Vioque, Jesús (Universidad Miguel Hernández de Elche) ;
Corella, Dolores (Universitat de València) ;
Fitó, Montserrat (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vidal, Josep (Hospital Clínic i Provincial de Barcelona) ;
Moreno-Indias, Isabel (Hospital Universitario Virgen de la Vic) ;
Pertusa-Martinez, Salvador (Centro Salud Cabo Huertas) ;
Álvarez-Sala, Andrea (Universitat de València) ;
Castañer, Olga (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Goday Arnó, Albert (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Damas-Fuentes, Miguel (Hospital Universitario Virgen de la Vic) ;
Belzer, Clara (Wageningen University) ;
Martínez-Gonzalez, Miguel Á. (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Hu, Frank B. (Harvard Medical School) ;
Salas-Salvadó, Jordi (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición) ;
Universitat Autònoma de Barcelona
The production and consumption of ultra-processed foods (UPF) has increased considerably during the last years worldwide. Collective evidence shows the association between UPF consumption and adverse health outcomes, including inflammatory gastro-intestinal disorders and obesity. [...]
2022 - 10.3389/fnut.2022.976547
Frontiers in nutrition, Vol. 9 (october 2022)
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3.
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15 p, 1.1 MB |
One-year longitudinal association between changes in dietary choline or betaine intake and cardiometabolic variables in the PREvención con DIeta MEDiterránea-Plus (PREDIMED-Plus) trial
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Díez-Ricote, Laura ;
San-Cristobal, Rodrigo ;
Concejo, M José ;
Martínez-González, Miguel Á ;
Corella, Dolores ;
Salas-Salvadó, Jordi ;
Goday Arnó, Albert (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Martínez, J Alfredo ;
Alonso-Gómez, Ángel María ;
Wärnberg, Julia ;
Vioque, Jesús ;
Romaguera, Dora ;
López-Miranda, José ;
Estruch, Ramón (Hospital Clínic i Provincial de Barcelona) ;
Tinahones, Francisco J.. ;
Lapetra, José ;
Serra-Majem, Luís ;
Bueno-Cavanillas, Aurora ;
Tur, Josep A. ;
Martín, Vicente ;
Pintó, Xavier (Hospital Universitari de Bellvitge) ;
Gaforio, José J ;
Matía-Martín, Pilar ;
Vidal, Josep (Hospital Universitari de Bellvitge) ;
Mas Fontao, Sebastián ;
Ros, Emilio (Hospital Clínic i Provincial de Barcelona) ;
Vázquez-Ruiz, Zenaida ;
Ortega-Azorín, Carolina ;
García-Gavilán, Jesús F ;
Malcampo Manrúbia, Mireia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Martínez-Urbistondo, Diego ;
Tojal-Sierra, Lucas ;
García Rodríguez, Antonio ;
Gómez-Bellvert, Nuria ;
Chaplin, Alice ;
García-Rios, Antonio ;
Bernal-López, Rosa M ;
Santos-Lozano, José M ;
Basterra-Gortari, Javier ;
Sorlí, José V ;
Murphy, Michelle ;
Gasulla, Griselda (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Micó, Víctor ;
Salaverria-Lete, Itziar ;
Goñi Ochandorena, Estibaliz ;
Babio, Nancy ;
Herraiz, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ordovás, José M ;
Daimiel, Lidia ;
Universitat Autònoma de Barcelona
Choline and betaine intakes have been related to cardiovascular health. We aimed to explore the relation between 1-y changes in dietary intake of choline or betaine and 1-y changes in cardiometabolic and renal function traits within the frame of the PREDIMED (PREvención con DIeta MEDiterránea)-Plus trial. [...]
2022 - 10.1093/ajcn/nqac255
The American Journal of Clinical Nutrition, Vol. 116 (september 2022) , p. 1565-1579
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14 p, 1.9 MB |
Safety, efficacy, and pharmacokinetics of gremubamab (MEDI3902), an anti-Pseudomonas aeruginosa bispecific human monoclonal antibody, in P. aeruginosa-colonised, mechanically ventilated intensive care unit patients : a randomised controlled trial
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Chastre, Jean (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
François, Bruno (Réanimation Polyvalente and Inserm CIC 1435 & UMR 1092. CHU) ;
Bourgeois, Marc (AZ Sint-Jan Brugge-Oostende AV) ;
Komnos, Apostolos (General Hospital of Larissa) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron) ;
Rahav, Galia (Chaim Sheba Medical Center. Sackler School of Medicine. Tel Aviv University) ;
De Schryver, Nicolas (Clinique Saint-Pierre) ;
Lepape, Alain (Hospices Civils de Lyon Hôpital Lyon Sud) ;
Koksal, Iftihar (Faculty of Medicine. Trabzon and Acibadem University Faculty of Medicine. Karadeniz Technical University) ;
Luyt, Charles-Edouard (Service de Médecine Intensive Réanimation. Institut de Cardiologie. Groupe Hospitalier Pitié-Salpêtrière. Assistance Publique-Hôpitaux de Paris. Sorbonne University) ;
Sánchez-García, Miguel (Hospital Clínico San Carlos. Unidad de Cuidados Intensivos) ;
Torres, Antoni (Hospital Clínic i Provincial de Barcelona. Servei de Pneumologia) ;
Eggimann, Philippe (Department of Locomotor Apparatus. Centre Hospitalier Universitaire Vaudois CHUV) ;
Koulenti, Despoina (2nd Critical Care Department. Attikon University Hospital. National and Kapodistrian. University of Athens) ;
Holland, Thomas L. (Duke Clinical Research Institute) ;
Ali, Omar (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Shoemaker, Kathryn (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Ren, Pin (Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Sauser, Julien (Infection Control Program. Faculty of Medicine. Geneva University Hospitals) ;
Ruzin, Alexey (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Tabor, David E. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Akhgar, Ahmad (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Wu, Yuling (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
Jiang, Yu (Clinical Pharmacology and Quantitative Pharmacology. Clinical Pharmacology and Safety Sciences. BioPharmaceuticals R&D. AstraZeneca) ;
DiGiandomenico, Antonio (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Colbert, Susan (Oncology. US SM&M. AstraZeneca) ;
Vandamme, Drieke (Inserm CIC 1435. CHU) ;
Coenjaerts, Frank (University Medical Center Utrecht) ;
Malhotra-Kumar, Surbhi (University of Antwerp. Laboratory of Medical Microbiology) ;
Timbermont, Leen (University of Antwerp. Laboratory of Medical Microbiology) ;
Oliver, Antonio (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Barraud, Olivier (INSERM U1092. Centre Hospitalier Universitaire de Limoges. Université Limoges) ;
Bellamy, Terramika (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Bonten, Marc (Julius Center for Health Science and Primary Care. University Medical Center Utrecht. Utrecht University) ;
Goossens, Herman (Laboratory of Medical Microbiology. Vaccine and Infectious Disease Institute. University of Antwerp) ;
Reisner, Colin (DevPro Biopharma) ;
Esser, Mark T. (Clinical Research and Development. Vaccines and Immune Therapies. BioPharmaceuticals R&D. AstraZeneca Biopharmaceuticals) ;
Jafri, Hasan S. (Late-Stage Development. Respiratory and Immunology. BioPharmaceuticals R&D. AstraZeneca) ;
Joannidis, Michael ;
Klimscha, Walter ;
De Waele, Elisabeth ;
Devriendt, Jacques ;
Huberlant, Vincent ;
Depuydt, Pieter ;
Van Boxstael, Sam ;
Peric, Mladen ;
Kopic, Jasminka ;
Hanauer, Michal ;
Hruby, Tomas ;
Sramek, Vladimir ;
Svoboda, Petr ;
Vymazal, Tomas ;
Novacek, Martin ;
Annane, Djillali ;
Mira, Jean-Paul ;
Souweine, Bertrand ;
Dequin, Pierre-François ;
Meziani, Ferhat ;
Stephan, François ;
Nseir, Saad ;
Gibot, Sebastien ;
Schwebel, Carole ;
Plantefeve, Gaetan ;
Diehl, Jean-Luc ;
Richard, Christian ;
Lamer, Christian ;
Klouche, Kada ;
Jaber, Samir ;
Zakynthinos, Epaminondas ;
Filntisis, Georgios ;
Zakynthinos, Spyros ;
Koutsoukou, Antonia ;
Saroglou, Georgios ;
Nikolaou, Charikleia ;
Vlachogianni, Glykeria ;
Pnevmatikos, Ioannis ;
Mandragos, Konstantinos ;
Kremer, Ildiko ;
Rozgonyi, Zsolt Dezso ;
Marjanek, Zsuzsa ;
Martin-Loeches, Ignacio ;
Singer, Pierre ;
Van Heerden, Vernon ;
Carmeli, Yehuda ;
Povoa, Pedro ;
AlvarezSeoane, Antonio ;
Moura, Pedro ;
Gonzalez, Filipe ;
Ramirez, Paula ;
Torres Marti, Antonio ;
Ferrer Roca, Ricard ;
Oteiza, Lorena ;
Escudero, Dolores ;
Piacentini, Enrique ;
Vera-Artazcoz, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
Tamayo, Luis ;
Gonzalez Gallego, Miguel Angel ;
Suberviola Canas, Borja ;
Figueira, Iglesias ;
Leon, Rafael ;
Korten, Volkan ;
Akova, Murat ;
Wyncoll, Duncan ;
Whitehouse, Tony ;
Hopkins, Phil ;
Sim, Malcolm ;
Golan, Yoav ;
Zervos, Marcus ;
Vazquez, Jose ;
Cherabuddi, Kartikeya ;
Smulian, George ;
Rouphael, Nadine ;
Welker, James ;
Sims, Mathew ;
Van Duin, David ;
McCarthy, Todd ;
Polk, Christopher
Background: Ventilator-associated pneumonia caused by Pseudomonas aeruginosa (PA) in hospitalised patients is associated with high mortality. The effectiveness of the bivalent, bispecific mAb MEDI3902 (gremubamab) in preventing PA nosocomial pneumonia was assessed in PA-colonised mechanically ventilated subjects. [...]
2022 - 10.1186/s13054-022-04204-9
Critical Care, Vol. 26 Núm. 1 (december 2022) , p. 355
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15 p, 1.0 MB |
Insights into Insulin Resistance and Calcification in the Myocardium in Type 2 Diabetes : A Coronary Artery Analysis
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Martín-Saladich, Queralt (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Aguadé-Bruix, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Simó-Servat, Olga (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Aparicio-Gómez, Carolina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramirez-Serra, Clara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pizzi, María Nazarena (Universitat de Barcelona. Departament de Medicina) ;
Roque, Albert (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
González Ballester, Miguel A. (Universitat Pompeu Fabra) ;
Herance, José Raul (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Type 2 diabetes (T2D) is responsible for high incidence of cardiovascular (CV) complications leading to heart failure. Coronary artery region-specific metabolic and structural assessment could provide deeper insight into the extent of the disease and help prevent adverse cardiac events. [...]
2023 - 10.3390/ijms24043250
International journal of molecular sciences, Vol. 24 (february 2023)
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11 p, 1.3 MB |
Agreement between two photoplethysmography-based wearable devices for monitoring heart rate during different physical activity situations : a new analysis methodology
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Alfonso, Carla (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Garcia-Gonzalez, Miguel A. (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ;
Parrado Romero, Eva (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Gil-Rojas, Jessyca (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ;
Ramos-Castro, Juan (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ;
Capdevila Ortís, Lluís (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ;
Universitat Autònoma de Barcelona.
Institut de Recerca de l'Esport
Wearables are being increasingly used to monitor heart rate (HR). However, their usefulness for analyzing continuous HR in research or at clinical level is questionable. The aim of this study is to analyze the level of agreement between different wearables in the measurement of HR based on photoplethysmography, according to different body positions and physical activity levels, and compared to a gold-standard ECG. [...]
2022 - 10.1038/s41598-022-18356-9
Scientific reports, Vol. 12 (september 2022)
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19 p, 1.6 MB |
Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial : A cross-sectional analysis
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Rosique-Esteban, Nuria (Instituto de Salud Carlos III) ;
Díaz-López, Andrés (Instituto de Salud Carlos III) ;
Martínez-González, Miguel A. (Instituto de Salud Carlos III) ;
Corella, Dolores (Instituto de Salud Carlos III) ;
Goday Arnó, Albert (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Martínez, J. Alfredo (Instituto de Salud Carlos III) ;
Romaguera, Dora (Instituto de Salud Carlos III) ;
Vioque, Jesús (Universidad Miguel Hernández, Alicante) ;
Arós, Fernando (University Hospital Araba, Vitoria) ;
García-Rios, Antonio (Universitat de Còrdoba) ;
Tinahones, Francisco (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Estruch, Ramón (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fernández-García, José Carlos (Universidad de Málaga) ;
Lapetra, José (Distrito Sanitario Atencion Primaria Sevilla) ;
Serra-Majem, Luís (Universitat de Las Palmas de Gran Canaria) ;
Pinto, Xavier (Institut d'Investigació Biomèdica de Bellvitge) ;
Tur, Josep A. (University of the Balearic Islands) ;
Bueno-Cavanillas, Aurora (Instituto de Salud Carlos III) ;
Vidal, Josep (Hospital Clínic i Provincial de Barcelona) ;
Delgado-Rodríguez, Miguel (Universitat de Jaen) ;
Daimiel, Lidia (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Vázquez, Clotilde (Hospital Universitario Fundación Jiménez Díaz) ;
Rubio Herrera, Miguel Ángel (Instituto de Investigación Sanitaria del Hospital Clínico San Carlos) ;
Ros, Emilio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Salas-Salvadó, Jordi (Instituto de Salud Carlos III)
Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. [...]
2017 - 10.1371/journal.pone.0172253
PloS one, Vol. 12 (march 2017)
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25 p, 5.7 MB |
Human-induced neural and mesenchymal stem cell therapy combined with a curcumin nanoconjugate as a spinal cord injury treatment
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Bonilla, Pablo (Centro de Investigación Príncipe Felipe (València)) ;
Hernández Martín, Joaquim (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Giraldo, Esther (Universitat Politècnica de València. Departament de Biotecnologia) ;
González-Pérez, Miguel A. (Centro de Investigación Príncipe Felipe (València)) ;
Alastrue-Agudo, Ana (Centro de Investigación Príncipe Felipe (València)) ;
Elkhenany, Hoda (Centro de Investigación Príncipe Felipe (València)) ;
Vicent, María J. (Centro de Investigación Príncipe Felipe. Laboratorio de Terapéutica de Polímeros) ;
Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Edel, Michael J.. (Institut Barraquer. Laboratori de Medicina Regenerativa) ;
Moreno-Manzano, Victoria (Centro de Investigación Príncipe Felipe (València))
We currently lack effective treatments for the devastating loss of neural function associated with spinal cord injury (SCI). In this study, we evaluated a combination therapy comprising human neural stem cells derived from induced pluripotent stem cells (iPSC-NSC), human mesen-chymal stem cells (MSC), and a pH-responsive polyacetal-curcumin nanoconjugate (PA-C) that al-lows the sustained release of curcumin. [...]
2021 - 10.3390/ijms22115966
International journal of molecular sciences, Vol. 22, Issue 11 (June 2021) , art. 5966
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11 p, 1.3 MB |
Metabolites related to purine catabolism and risk of type 2 diabetes incidence; modifying effects of the TCF7L2-rs7903146 polymorphism
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Papandreou, Christopher (Institut d'Investigació Sanitària Pere Virgili) ;
Li, Jun (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Liang, Liming (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Bulló, Mònica (Institut d'Investigació Sanitària Pere Virgili) ;
Zheng, Yan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Ruiz-Canela, Miguel (Universidad de Navarra) ;
Yu, Edward (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Guasch-Ferré, Marta (Institut d'Investigació Sanitària Pere Virgili) ;
Razquin, Cristina (Universidad de Navarra) ;
Clish, Clary (Massachusetts Institute of Technology) ;
Corella, Dolores (Universitat de València) ;
Estruch, Ramón (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ros, Emilio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Fitó, Montserrat (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Arós, Fernando (Arabako Unibertsitate Ospitalea) ;
Serra-Majem, Lluís (Universidad de Las Palmas de Gran Canaria) ;
Rosique, Nuria (Institut d'Investigació Sanitària Pere Virgili) ;
Martínez-González, Miguel A. (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Hu, Frank B. (Harvard Medical School) ;
Salas-Salvadó, Jordi (Institut d'Investigació Sanitària Pere Virgili) ;
Universitat Autònoma de Barcelona
Studies examining associations between purine metabolites and type 2 diabetes (T2D) are limited. We prospectively examined associations between plasma levels of purine metabolites with T2D risk and the modifying effects of transcription factor-7-like-2 (TCF7L2) rs7903146 polymorphism on these associations. [...]
2019 - 10.1038/s41598-019-39441-6
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 2892
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