Resultados globales: 9 registros encontrados en 0.02 segundos.
Artículos, Encontrados 9 registros
Artículos Encontrados 9 registros  
1.
13 p, 10.6 MB Exploiting endocytosis for transfection of mRNA for cytoplasmatic delivery using cationic gold nanoparticles / Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ; Edel, Michael J (Universitat Autònoma de Barcelona) ; Salazar Montoya, Vivian Angélica (Institut Català de Nanociència i Nanotecnologia) ; Alvarez-Palomo, Belén (Banc de Sang i Teixits) ; Juan, Manel (Hospital Clínic i Provincial de Barcelona) ; Broggini, Massimo (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ; Damia, Giovanna (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ; Bigini, Paolo (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ; Corbelli, Alessandro (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ; Fiordaliso, Fabio (IRCCS-Istituto di Ricerche Farmacologiche Mario Negri) ; Barbul, Alexander (Tel Aviv University) ; Korenstein, Rafi (Tel Aviv University) ; Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Gene therapy holds promise to cure various diseases at the fundamental level. For that, efficient carriers are needed for successful gene delivery. Synthetic 'non-viral' vectors, as cationic polymers, are quickly gaining popularity as efficient vectors for transmitting genes. [...]
2023 - 10.3389/fimmu.2023.1128582
Frontiers in immunology, Vol. 14 (May 2023) , art. 1128582  
2.
16 p, 3.2 MB In Vitro Antibacterial Activity of Silver Nanoparticles Conjugated with Amikacin and Combined with Hyperthermia against Drug-Resistant and Biofilm-Producing Strains / Palau Gauthier, Marta (Hospital Universitari Vall d'Hebron) ; Muñoz, Estela (Hospital Universitari Vall d'Hebron) ; Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ; Larrosa, María Nieves (Hospital Universitari Vall d'Hebron) ; Gomis, Xavier (Hospital Universitari Vall d'Hebron) ; Gilabert, Joan (Tractivus SL) ; Almirante Gragera, Benito (Hospital Universitari Vall d'Hebron) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Texidó, Robert (Institució Catalana de Recerca i Estudis Avançats) ; Gavaldà, Joan (Hospital Universitari Vall d'Hebron)
In view of the current increase and spread of antimicrobial resistance (AMR), there is an urgent need to find new strategies to combat it. This study had two aims. First, we synthesized highly monodispersed silver nanoparticles (AgNPs) of approximately 17 nm, and we functionalized them with mercaptopoly(ethylene glycol) carboxylic acid (mPEG-COOH) and amikacin (AK). [...]
2023 - 10.1128/spectrum.00280-23
Microbiology Spectrum, Vol. 11, Issue 3 (June 2023) , art. 00280-23  
3.
13 p, 1.9 MB Nanoceria as Safe Contrast Agents for X-ray CT Imaging / García, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cámara, Juan Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Boullosa, Ana María (Networking Research Centre on Bioengineering) ; Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ; Mondragón, Laura (Institut Català de Nanociència i Nanotecnologia) ; Schwartz, Simon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Casals, Eudald (Wuyi University) ; Abasolo, Ibane (Hospital Universitari Vall d'Hebron) ; Bastús, Neus G (Institut Català de Nanociència i Nanotecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Cerium oxide nanoparticles (CeONPs) have exceptional catalytic properties, rendering them highly effective in removing excessive reactive oxygen species (ROS) from biological environments, which is crucial in safeguarding these environments against radiation-induced damage. [...]
2023 - 10.3390/nano13152208
Nanomaterials, Vol. 13, Issue 15 (August 2023) , art. 2208  
4.
20 p, 4.6 MB Exploring the Long-Term Tissue Accumulation and Excretion of 3 nm Cerium Oxide Nanoparticles after Single Dose Administration / Ernst, Lena M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Mondragón, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ramis, Joana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gustà, Muriel F. (Institut Català de Nanociència i Nanotecnologia) ; Yudina, Tetyana (Institut Català de Nanociència i Nanotecnologia) ; Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Fernández-Varo, Guillermo (Hospital Clínic i Provincial de Barcelona) ; Casals, Gregori (Hospital Clínic i Provincial de Barcelona) ; Jiménez, Wladimiro (Hospital Clínic i Provincial de Barcelona) ; Puntes, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Nanoparticle (NP) pharmacokinetics significantly differ from traditional small molecule principles. From this emerges the need to create new tools and concepts to harness their full potential and avoid unnecessary risks. [...]
2023 - 10.3390/antiox12030765
Antioxidants, Vol. 12, Issue 3 (March 2023) , art. 765  
5.
26 p, 1.5 MB The Role of common cell culture media supplements on citrate-stabilized gold nanoparticle protein corona formation, aggregation state, and the consequent impact on cellular uptake / Barbero, Francesco (Institut Català de Nanociència i Nanotecnologia) ; Michelini, Sara (University of Salzburg. Department of Biosciences) ; Moriones, Oscar Hernando (Universitat Autònoma de Barcelona) ; Patarroyo, Javier (Institut Català de Nanociència i Nanotecnologia) ; Rosell Aluja, Jordi 1955- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gustà, Muriel F (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vitali, Michele (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martín, Luna (Vall d'Hebron Institut d'Oncologia) ; Canals, Francesc (Vall d'Hebron Institut d'Oncologia) ; Duschl, Albert (University of Salzburg. Department of Biosciences) ; Horejs-Hoeck, Jutta (University of Salzburg. Department of Biosciences) ; Mondragón, Laura (Institut Català de Nanociència i Nanotecnologia) ; Bastús, Neus G. (Institut Català de Nanociència i Nanotecnologia) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Sodium citrate-stabilized gold nanoparticles (AuNPs) are destabilized when dispersed in cell culture media (CCMs). This may promote their aggregation and subsequent sedimentation, or under the proper conditions, their interaction with dispersed proteins can lead to the formation of a NP-stabilizing protein corona. [...]
2022 - 10.1021/acs.bioconjchem.2c00232
Bioconjugate chemistry, Vol. 33, issue 8 (Aug. 2022) , p. 1505-1514  
6.
32 p, 1.4 MB Epigenetics in Breast Cancer Therapy-New Strategies and Future Nanomedicine Perspectives / Buocikova, Verona (Biomedical Research Center of the Slovak Academy of Sciences) ; Rios-Mondragon, Ivan (University of Bergen) ; Pilalis, Eleftherios (Biomedical Research Foundation of the Academy of Athens) ; Chatziioannou, Aristotelis (Biomedical Research Foundation of the Academy of Athens) ; Miklikova, Svetlana (Biomedical Research Center of the Slovak Academy of Sciences) ; Mego, Michal (Comenius University and National Cancer Institute) ; Pajuste, Karlis (Latvian Institute of Organic Synthesis) ; Rucins, Martins (Latvian Institute of Organic Synthesis) ; Yamani, Naouale El (NILU-Norwegian Institute for Air Research) ; Longhin, Eleonora Marta (NILU-Norwegian Institute for Air Research) ; Sobolev, Arkadij (Latvian Institute of Organic Synthesis) ; Gustà, Muriel F (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Plotniece, Aiva (Latvian Institute of Organic Synthesis) ; Dusinska, Maria (NILU-Norwegian Institute for Air Research) ; Cimpan, Mihaela Roxana (University of Bergen) ; Gabelova, Alena (Slovak Academy of Sciences) ; Smolkova, Bozena (Slovak Academy of Sciences) ; Universitat Autònoma de Barcelona
Despite advances in cancer treatment, difficult-to-treat tumor subtypes remain a challenge. New multidisciplinary approaches can help overcome current obstacles posed by tumor heterogeneity, activation and enrichment of cancer stem cells, and acquired drug resistance development. [...]
2020 - 10.3390/cancers12123622
Cancers, Vol. 12 (december 2020)  
7.
1 p, 83.7 KB Corrigendum : Intrinsic and extrinsic properties affecting innate immune responses to nanoparticles: The case of cerium oxide / Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gusta, Muriel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Piella, Jordi (Institut Català de Nanociència i Nanotecnologia) ; Casals, Gregori (Hospital Clínic i Provincial de Barcelona) ; Jiménez Povedano, Wladimiro (Universitat de Barcelona. Departament de Biomedicina) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
In the original article, we overlooked to include the FutureNanoNeeds Project financed by the European Community under the FP7 Programme under Grant Agreement No. 604602 (FP7-NMP-2013-LARGE-7, Grant Agreement No. [...]
2017 - 10.3389/fimmu.2017.01891
Frontiers in immunology, Vol. 8 (December 2017) , art. 1891  
8.
7 p, 765.9 KB Intrinsic and extrinsic properties affecting innate immune responses to nanoparticles : The case of cerium oxide / Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gusta, Muriel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Piella, Jordi (Institut Català de Nanociència i Nanotecnologia) ; Casals, Gregori (Hospital Clínic i Provincial de Barcelona) ; Jiménez Povedano, Wladimiro (Universitat de Barcelona. Departament de Biomedicina) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
We review the apparent discrepancies between studies that report anti-inflammatory effects of cerium oxide nanoparticles (CeO NPs) through their reactive oxygen specieschelating properties and immunological studies highlighting their toxicity. [...]
2017 - 10.3389/fimmu.2017.00970
Frontiers in immunology, Vol. 8 (August 2017) , art. 970  
9.
19 p, 1.2 MB Cancer resistance to treatment and antiresistance tools offered by multimodal multifunctional nanoparticles / Casals, Eudald (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gusta, Muriel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cobaleda-Siles, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia-Sanz, Ana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia)
Chemotherapeutic agents have limited efficacy and resistance to them limits today and will limit tomorrow our capabilities of cure. Resistance to treatment with anticancer drugs results from a variety of factors including individual variations in patients and somatic cell genetic differences in tumours. [...]
2017 - 10.1186/s12645-017-0030-4
Cancer Nanotechnology, Vol. 8, issue 1 (2017) , art. 7  

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