Home > Search Results: Hancock, Gemma
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Articles, 2 records found
Articles 2 records found  
1.
11 p, 1018.7 KB Evaluation of the immunogenicity and impact on the latent HIV-1 reservoir of a conserved region vaccine, MVA.HIVconsv, in antiretroviral therapy-treated subjects / Hancock, Gemma ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kopycinski, Jakub ; Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Giannoulatou, Eleni (University of New South Wales) ; Rose, Annie ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hayton, Emma-Jo ; Crook, Alison ; Morgan, Catharine ; Angus, Brian ; Chen, Fabian ; Yang, Hongbing ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomáš ; Dorrell, Lucy ; Universitat Autònoma de Barcelona
Introduction : Vaccines may be key components of a curative strategy for HIV-1. We investigated whether a novel immunogen, HIVconsv, designed to re-direct T cell responses to conserved viral epitopes, could impact the HIV-1 reservoir in chronic antiretroviral therapy (ART)-treated subjects when delivered by modified vaccinia virus Ankara (MVA). [...]
2017 - 10.7448/IAS.20.1.21171
Journal of the International AIDS Society, Vol. 20 (may 2017)  
Detailed record - Creative Commons
2.
22 p, 877.6 KB Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses / Hancock, Gemma (University of Oxford) ; Yang, Hongbing (University of Oxford) ; Yorke, Elisabeth (University of Toronto) ; Wainwright, Emma (Royal Berkshire NHS Foundation Trust (Reading, Gran Bretanya)) ; Bourne, Victoria (University of Oxford) ; Frisbee, Alyse (Duke University (Durham, Estats Units d'Amèrica)) ; Payne, Tamika L. (Duke University (Durham, Estats Units d'Amèrica)) ; Berrong, Mark (Duke University (Durham, Estats Units d'Amèrica)) ; Ferrari, Guido (Duke University (Durham, Estats Units d'Amèrica)) ; Chopera, Denis (University of Cape Town) ; Hanke, Tomáš (University of Oxford) ; Mothe, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Brander, Christian (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; McElrath, M. Juliana (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; McMichael, Andrew (University of Oxford) ; Goonetilleke, Nilu (University of North Carolina School of Medicine) ; Tomaras, Georgia D. (Duke University (North Carolina, Estats Units d'Amèrica)) ; Frahm, Nicole (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ; Dorrell, Lucy (University of Oxford)
Abstract. Defining the components of an HIV immunogen that could induce effective CD8+ T cell responses is critical to vaccine development. We addressed this question by investigating the viral targets of CD8+ T cells that potently inhibit HIV replication in vitro, as this is highly predictive of virus control in vivo. [...]
2015 - 10.1371/journal.ppat.1004658
PLOS pathogens, Vol. 11 Núm. 2 (february 2015)  
Detailed record - Creative Commons

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