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Resultats globals: 3 registres trobats en 0.03 segons.
Articles, 3 registres trobats
Articles 3 registres trobats  
1.
11 p, 2.9 MB Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis / Narasimhan, Rekha (University of California) ; Coras, Roxana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rosenthal, Sara B. (University of California) ; Sweeney, Shannon R. (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Lodi, Alessia (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Tiziani, Stefano (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Boyle, David (University of California. Division of Rheumatology) ; Kavanaugh, Arthur (University of California) ; Guma, Monica 1971- (Universitat Autònoma de Barcelona. Departament de Medicina)
Metabolomics is an emerging field of biomedical research that may offer a better understanding of the mechanisms of underlying conditions including inflammatory arthritis. Perturbations caused by inflamed synovial tissue can lead to correlated changes in concentrations of certain metabolites in the synovium and thereby function as potential biomarkers in blood. [...]
2018 - 10.1186/s13075-018-1655-3
Arthritis research & therapy, Vol. 20 (august 2018)  
Registre complet - Creative Commons
2.
13 p, 2.0 MB Differences in oxylipin profile in psoriasis versus psoriatic arthritis / Coras, Roxana (Universitat Autònoma de Barcelona) ; Kavanaugh, Arthur (University of California San Diego. Department of Medicine) ; Kluzniak, Angela (University of Rochester. Department of Medicine) ; Holt, Dustina (University of Rochester. Department of Medicine) ; Weilgosz, Amy (University of Rochester. Department of Medicine) ; Aaron, Armando (University of California San Diego. Department of Pharmacology) ; Quehenberger, Oswald (University of California San Diego. Department of Pharmacology) ; Ritchlin, Christopher (University of Rochester. Department of Medicine) ; Guma, Monica 1971- (Universitat Autònoma de Barcelona)
Oxylipins are biological lipids that have been implicated in inflammation. We previously found that certain oxylipins correlated with clinical manifestations in psoriatic arthritis (PsA) patients. Here, we compare oxylipin profiles in PsA patients and those with psoriasis (PsO) without inflammatory arthritis to identify oxylipins that associate with specific disease manifestations to better understand disease pathogenesis and identify new biomarkers. [...]
2021 - 10.1186/s13075-021-02575-y
Arthritis research & therapy, Vol. 23 (july 2021)  
Registre complet - Creative Commons
3.
11 p, 255.5 KB Maintenance of clinical efficacy and radiographic benefit through two years of ustekinumab therapy in patients with active psoriatic arthritis : results from a randomized, placebo-controlled phase III trial / Kavanaugh, Arthur (University of California) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Gottlieb, Alice B. (Tufts Medical Center) ; Ritchlin, Christopher (University of Rochester) ; Li, Shu (Janssen Pharmaceutica) ; Wang, Yuhua (Janssen Pharmaceutica) ; Mendelsohn, Alan M. (Janssen Pharmaceutica) ; Song, Michael (Janssen Pharmaceutica) ; Zhu, Yaowei (Janssen Pharmaceutica) ; Rahman, Proton (Memorial University of Newfoundland) ; McInnes, Iain B. (University of Glasgow) ; Universitat Autònoma de Barcelona
To evaluate the efficacy and safety of ustekinumab through 2 years in adult patients with active psoriatic arthritis (PsA). A total of 615 adult patients with active PsA were randomized to placebo, ustekinumab 45 mg, or ustekinumab 90 mg, at weeks 0, 4, and every 12 weeks through week 88 (last dose). [...]
2015 - 10.1002/acr.22645
Arthritis Care & Research, Vol. 67, issue 12 (Dec. 2015) , p. 1739-1749  
Registre complet - Creative Commons

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