Resultados globales: 5 registros encontrados en 0.01 segundos.
Artículos, Encontrados 5 registros
Artículos Encontrados 5 registros  
1.
10 p, 1.4 MB Assessment of transfer methods for comparative genomics of regulatory networks in Bacteria / Kılıç, Sefa (University of Maryland Baltimore County. Department of Biological Sciences) ; Erill, Ivan (University of Maryland Baltimore County. Department of Biological Sciences)
Background: Comparative genomics can leverage the vast amount of available genomic sequences to reconstruct and analyze transcriptional regulatory networks in Bacteria, but the efficacy of this approach hinges on the ability to transfer regulatory network information from reference species to the genomes under analysis. [...]
2016 - 10.1186/s12859-016-1113-7
BMC bioinformatics, Vol. 17, Suppl. 8 (August 2016) , art. 277  
2.
10 p, 992.7 KB From data repositories to submission portals: rethinking the role of domain-specific databases in CollecTF / Kılıç, Sefa (University of Maryland Baltimore County. Department of Biological Sciences) ; Sagitova, Dinara M. (University of Maryland Baltimore County. Department of Biological Sciences) ; Wolfish, Shoshannah (University of Maryland School ofMedicine) ; Bely, Benoit (European Bioinformatics Institute) ; Courtot, Mélanie (European Bioinformatics Institute) ; Ciufo, Stacy (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Tatusova, Tatiana (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; O'Donovan Claire (European Bioinformatics Institute) ; Chibucos, Marcus C. (University of Maryland School of Medicine. Department of Microbiology and Immunology) ; Martin, Maria J. (European Bioinformatics Institute) ; Erill, Ivan (University of Maryland Baltimore County. Department of Biological Sciences)
Domain-specific databases are essential resources for the biomedical community, leveraging expert knowledge to curate published literature and provide access to referenced data and knowledge. The limited scope of these databases, however, poses important challenges on their infrastructure, visibility, funding and usefulness to the broader scientific community. [...]
2016 - 10.1093/database/baw055
Database, Vol. 2016 (April 2016) , art. baw055  
3.
5 p, 4.0 MB CollecTF : a database of experimentally-validated transcription factor-binding sites in Bacteria / Kılıç, Sefa (University of Maryland Baltimore County. Department of Biological Sciences) ; White, Elliot R. (University of Maryland Baltimore County. Department of Biological Sciences) ; Sagitova, Dinara M. (University of Maryland Baltimore County. Department of Biological Sciences) ; Cornish, Joseph P. (University of Maryland Baltimore County. Department of Biological Sciences) ; Erill, Ivan (University of Maryland Baltimore County. Department of Biological Sciences)
The influx of high-throughput data and the need for complex models to describe the interaction of prokaryotic transcription factors (TF) with their target sites pose new challenges for TF-binding site databases. [...]
2014 - 10.1093/nar/gkt1123
Nucleic Acids Research, Vol. 42, Issue D1 (January 2014) , p. D156-D160  
4.
11 p, 2.9 MB Flexible comparative genomics of prokaryotic transcriptional regulatory networks / Kılıç, Sefa (University of Maryland Baltimore County) ; Sánchez-Osuna, Miquel (Universitat Autònoma de Barcelona) ; Collado-Padilla, Antonio (Universitat Autònoma de Barcelona) ; Barbé García, Jordi (Universitat Autònoma de Barcelona) ; Erill, Ivan (University of Maryland Baltimore County)
Comparative genomics methods enable the reconstruction of bacterial regulatory networks using available experimental data. In spite of their potential for accelerating research into the composition and evolution of bacterial regulons, few comparative genomics suites have been developed for the automated analysis of these regulatory systems. [...]
2020 - 10.1186/s12864-020-06838-x
BMC genomics, Vol. 21, Suppl. 5 (December 2020) , art. 466  
5.
13 p, 5.2 MB The Verrucomicrobia LexA-Binding Motif : Insights into the Evolutionary Dynamics of the SOS Response / Erill, Ivan (University of Maryland Baltimore County. Erill Lab, Department of Biological Sciences) ; Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kiliç, Sefa (University of Maryland Baltimore County. Erill Lab, Department of Biological Sciences) ; Barbé García, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The SOS response is the primary bacterial mechanism to address DNA damage, coordinating multiple cellular processes that include DNA repair, cell division, and translesion synthesis. In contrast to other regulatory systems, the composition of the SOS genetic network and the binding motif of its transcriptional repressor, LexA, have been shown to vary greatly across bacterial clades, making it an ideal system to study the co-evolution of transcription factors and their regulons. [...]
2016 - 10.3389/fmolb.2016.00033
Frontiers in Molecular Biosciences, Vol. 3 (july 2016) , art. 33  

Vea también: autores con nombres similares
1 Kilic, Sara S.
5 Kılıç, Sefa
1 Kılıç, Suna
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