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6 p, 2.2 MB Low-cost diagnostic test for susceptible and drug-resistant tuberculosis in rural Malawi / Zhang, Annie (The Ohio State University. Department of Microbiology, College of Arts and Sciences) ; Jumbe, Enoch (Child Legacy International, Msundwe, Lilongwe, Malawi) ; Krysiak, Robert (University of North Carolina Project. Department of Infectious Diseases) ; Sidiki, Sabeen (The Ohio State University. Department of Microbial Infection and Immunity) ; Kelley, Holden V. (The Ohio State University. Department of Microbial Infection and Immunity) ; Chemey, Elly K. (Child Legacy International, Msundwe, Lilongwe, Malawi) ; Kamba, Chancy (District Tuberculosis Control Office, Ministry of Health, Lilongwe, Malawi) ; Mwapasa, Victor (College of Medicine (Blantyre, Malawi). Department of Community Health) ; García, Juan Ignacio (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ; Norris, Alison (The Ohio State University. College of Public Health) ; Pan, Xueliang J. (The Ohio State University. Center for Biostatistics) ; Evans, Carlton (Unversidad Cayetano Heredia (Lima, Perú). Department of Microbiology) ; Wang, Shu-Hua (The Ohio State University. Division of Infectious Diseases) ; Kwiek, Jesse J. (The Ohio State University. Department of Microbiology) ; Torrelles, Jordi B. (The Ohio State University. Department of Microbial Infection and Immunity)
Rural settings where molecular tuberculosis diagnostics are not currently available need easy-to-use tests that do not require additional processing or equipment. While acid-fast bacilli (AFB) smear is the most common and often only tuberculosis diagnosis test performed in rural settings, it is labour intensive, has less-than-ideal sensitivity, and cannot assess tuberculosis drug susceptibility patterns. [...]
2018 - 10.4102/ajlm.v7i1.690
African Journal of Laboratory Medicine, Vol. 7 (june 2018)  
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