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15 p, 867.3 KB |
Cardiovascular disease in type 2 diabetes mellitus : progress toward personalized management
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Ma, Cheng-Xu (The First Clinical Medical College of Lanzhou University) ;
Ma, Xiao-Ni (The First Clinical Medical College of Lanzhou University) ;
Guan, Cong-Hui (The First Clinical Medical College of Lanzhou University) ;
Li, Ying-Dong (College of Integrated Traditional Chinese and Western Medicine. Gansu University of Chinese Medicine) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Fu, Song-Bo (The First Clinical Medical College of Lanzhou University) ;
Universitat Autònoma de Barcelona
Cardiovascular diseases (CVDs) are the main cause of death among patients with type 2 diabetes mellitus (T2DM), particularly in low- and middle-income countries. To effectively prevent the development of CVDs in T2DM, considerable effort has been made to explore novel preventive approaches, individualized glycemic control and cardiovascular risk management (strict blood pressure and lipid control), together with recently developed glucose-lowering agents and lipid-lowering drugs. [...]
2022 -  10.1186/s12933-022-01516-6
Cardiovascular diabetology, Vol. 21 Núm. 1 (december 2022) , p. 74
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35 p, 2.1 MB |
Modeling Fanconi anemia pathogenesis and therapeutics using integration-free patient iPSCs
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Liu, Guang-Hui (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Suzuki, Keiichiro (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Li, Mo (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Qu, Jing (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Montserrat, Núria (Centro de Medicina Regenerativa de Barcelona) ;
Tarantino, Carolina (Centro de Medicina Regenerativa de Barcelona) ;
Gu, Ying (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Yi, Fei (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Xu, Xiuling (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ;
Zhang, Weiqi (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ;
Ruiz, Sergio (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Plongthongkum, Nongluk (University of California. Department of Bioengineering) ;
Zhang, Kun (University of California. Department of Bioengineering) ;
Masuda, Shigeo (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Nivet, Emmanuel (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Tsunokawa, Yuji (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Soligalla, Rupa Devi (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Goebl, April (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Aizawa, Emi (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Kim, Na Young (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Kim, Jessica (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Dubova, Ilir (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Li, Ying (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ;
Ren, Ruotong (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ;
Benner, Chris (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica)) ;
Sol, Antonio del (Luxembourg Centre for Systems Biomedicine) ;
Bueren, Juan (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ;
Trujillo Quintero, Juan Pablo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Cappelli, Enrico (Istituto "Giannina Gaslini" di Genova) ;
Dufour, Carlo (Istituto "Giannina Gaslini" di Genova) ;
Rodriguez Esteban, Concepción (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ;
Izpisúa Belmonte, Juan Carlos (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression)
Fanconi anaemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow (BM) failure. However, the pathogenesis of FA is not fully understood partly due to the limitations of current disease models. [...]
Altres ajuts: Strategic Priority Research Program of the Chinese Academy of Sciences (XDA01020312), National Basic Research Program of China (973 Program,2014CB964600;2014CB910500), NSFC (81271266, 31222039, 81330008, 31201111, 81371342, 81300261, 81300677), Key Research Program of the Chinese Academy of Sciences (KJZD-EW-TZ-L05), Beijing Natural Science Foundation (7141005; 5142016), the Thousand Young Talents program of China, National Laboratory of Biomacromolecules (012kf02, 2013kf05;2013kf11;2014kf02), and State Key Laboratory of Drug Research (SIMM1302KF-17). [...]
2014 - 10.1038/ncomms5330
Nature communications, Vol. 5, article 4330 (July 2014)
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