Resultados globales: 10 registros encontrados en 0.03 segundos.
Artículos, Encontrados 10 registros
Artículos Encontrados 10 registros  
1.
20 p, 3.6 MB Improved mini-Tn 7 Delivery Plasmids for Fluorescent Labeling of / Mamat, Uwe (Research Center Borstel) ; Hein, Manuel (Research Center Borstel) ; Grella, Dörte (Research Center Borstel) ; Taylor, Claire S. (Research Center Borstel) ; Scholzen, Thomas (Research Center Borstel) ; Alio, Ifey (Universität Hamburg. Department of Microbiology and Biotechnology) ; Streit, Wolfgang R. (Universität Hamburg. Department of Microbiology and Biotechnology) ; Huedo Moreno, Pol (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Coves, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Conchillo-Solé, Oscar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Gómez Camacho, Andromeda Celeste (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gibert, Isidre (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Yero, Daniel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Schaible, Ulrich E. (Research Center Borstel)
Fluorescently labeled bacterial cells have become indispensable for many aspects of microbiological research, including studies on biofilm formation as an important virulence factor of various opportunistic bacteria of environmental origin such as . [...]
2023 - 10.1128/aem.00317-23
Applied and Environmental Microbiology, Vol. 89, Issue 6 (June 2023)  
2.
16 p, 7.0 MB Synthesis and evaluation of novel furanones as biofilm inhibitors in opportunistic human pathogens / Gómez Camacho, Andromeda Celeste (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Lyons, Thérèse (University College Cork. School of Pharmacy) ; Mamat, Uwe (Leibniz Lung Center. Cellular Microbiology) ; Yero, Daniel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Bravo, Marc (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Elshafee, Osama (Leibniz Institute for Natural Product Research and Infection Biology. Department of Microbial Pathogenicity Mechanisms) ; Brunke, Sascha (Leibniz Institute for Natural Product Research and Infection Biology. Department of Microbial Pathogenicity Mechanisms) ; Gahan, Cormac G.M. (University College Cork. APC Microbiome Ireland) ; O'Driscoll, Michelle (University College Cork. Analytical and Biological Chemistry Research Facility) ; Gibert, Isidre (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; O'Sullivan, Timothy P. (University College Cork. Analytical and Biological Chemistry Research Facility)
Diseases caused by biofilm-forming pathogens are becoming increasingly prevalent and represent a major threat to human health. This trend has prompted a search for novel inhibitors of microbial biofilms which could, for example, be used to potentiate existing antibiotics. [...]
2022 - 10.1016/j.ejmech.2022.114678
European Journal of Medicinal Chemistry, Vol. 242 (November 2022) , art. 114678  
3.
15 p, 1.6 MB Genetic Variants of the DSF Quorum Sensing System in Stenotrophomonas maltophilia Influence Virulence and Resistance Phenotypes Among Genotypically Diverse Clinical Isolates / Yero, Daniel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Huedo Moreno, Pol (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Conchillo-Solé, Oscar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Martínez-Servat, Sònia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Mamat, Uwe (Leibniz Lung Center) ; Coves, Xavier (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Llanas, Ferran (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Roca, Ignasi (Institut de Salut Global de Barcelona) ; Vila Estapé, Jordi (Institut de Salut Global de Barcelona) ; Schaible, Ulrich E. (Leibniz Lung Center) ; Daura i Ribera, Xavier (Institució Catalana de Recerca i Estudis Avançats) ; Gibert, Isidre (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The pathogenicity of Stenotrophomonas maltophilia is regulated in part by its quorum sensing (QS) system. The main QS signaling molecule in S. maltophilia is known as diffusible signal factor (DSF), and the rpf gene cluster is responsible for its synthesis and perception. [...]
2020 - 10.3389/fmicb.2020.01160
Frontiers in microbiology, Vol. 11 (June 2020) , art. 1160  
4.
12 p, 2.3 MB The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia / Gröschel, Matthias I. (University Medical Center Groningen. Department of Pulmonary Diseases & Tuberculosis) ; Meehan, Conor J. (University of Bradford. School of Chemistry and Bioscience) ; Barilar, Ivan (Research Center Borstel. Molecular and Experimental Mycobacteriology) ; Diricks, Margo (BioMérieux) ; Gonzaga, Aitor (Leibniz Institute DSMZ. German Collection of Microorganisms and Cell Cultures) ; Steglich, Matthias (Leibniz Institute DSMZ. German Collection of Microorganisms and Cell Cultures) ; Conchillo-Solé, Oscar (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Scherer, Isabell-Christin (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; Mamat, Uwe (Cellular Microbiology, Research Center Borstel) ; Luz, Christian F. (University Medical Center Groningen. Department of Medical Microbiology and Infection Prevention) ; De Bruyne, Katrien (bioMérieux, Applied Maths NV) ; Utpatel, Christian (Research Center Borstel. Molecular and Experimental Mycobacteriology) ; Yero, Daniel (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Gibert, Isidre (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Kampmeier, Stefanie (University Hospital of Münster (Alemanya)) ; Rahman, Nurdyana Abdul (Singapore General Hospital. Department of Microbiology) ; Kresken, Michael (Rheinische Fachhochschule Köln gGmbH) ; van der Werf, Tjip S. (University Medical Center Groningen. Department of Pulmonary Diseases & Tuberculosis) ; Alio, Ifey (University of Hamburg. Department of Microbiology and Biotechnology) ; Streit, Wolfgang R. (University of Hamburg. Department of Microbiology and Biotechnology) ; Zhou, Kai (Jinan University. Second Clinical Medical College) ; Schwartz, Thomas (Karlsruhe Institute of Technology) ; Rossen, John W. A. (University Medical Center Groningen. Department of Medical Microbiology and Infection Prevention) ; Farhat, Maha R. (Massachusetts General Hospital (Boston)) ; Schaible, Ulrich E. (Leibniz Research Alliance Infections'21) ; Nübel, Ulrich (Technical University. Braunschweig Integrated Center of Systems Biology) ; Rupp, Jan (German Center for Infection Research) ; Steinmann, Joerg (Paracelsus Medical Private University) ; Niemann, Stefan (Leibniz Research Alliance Infections'21) ; Kohl, Thomas A. (German Center for Infection Research)
Recent studies portend a rising global spread and adaptation of human- or healthcare-associated pathogens. Here, we analyse an international collection of the emerging, multidrug-resistant, opportunistic pathogen Stenotrophomonas maltophilia from 22 countries to infer population structure and clonality at a global level. [...]
2020 - 10.1038/s41467-020-15123-0
Nature communications, Vol. 11 (April 2020) , art. 2044  
5.
21 p, 4.1 MB Phenotypic and transcriptomic analyses of seven clinical Stenotrophomonas maltophilia isolates identify a small set of shared and commonly regulated genes involved in the biofilm lifestyle / Alio, Ifey (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Gudzuhn, Mirja (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Pérez García, Pablo (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Danso, Dominik (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Schoelmerich, Marie Charlotte (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Mamat, Uwe (Research Center Borstel. Priority Area Infections. Molecular and Experimental Mycobacteriology (Germany)) ; Schaible, Ulrich E. (Research Center Borstel. Priority Area Infections. Molecular and Experimental Mycobacteriology (Germany)) ; Steinmann, Jörg (Universitätsinstitut der Paracelsus Medizinischen Privatuniversität Klinikum Nürnberg. Institut für Klinikhygiene, Medizinische Mikrobiologie und Klinische Infektiologie (Germany)) ; Yero, Daniel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gibert, Isidre (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Kohl, Thomas A. (Research Center Borstel. Molecular and Experimental Mycobacteriology (Germany)) ; Niemann, Stefan (Research Center Borstel. Molecular and Experimental Mycobacteriology (Germany)) ; Gröschel, Matthias I. (Harvard Medical School. Department of Biomedical Informatics (USA)) ; Haerdter, Johanna (Universität Hamburg. Institute of Organic Chemistry (Germany)) ; Hackl, Thomas (Universität Hamburg. Institute of Organic Chemistry (Germany)) ; Vollstedt, Christel (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Bömeke, Mechthild (Georg-August University of Göttingen. Institute of Microbiology and Genetics. Department of Genomic and Applied Microbiology (Germany)) ; Egelkamp, Richard (Georg-August University of Göttingen. Institute of Microbiology and Genetics. Department of Genomic and Applied Microbiology (Germany)) ; Daniel, Rolf (Georg-August University of Göttingen. Institute of Microbiology and Genetics. Department of Genomic and Applied Microbiology (Germany)) ; Poehlein, Anja (Georg-August University of Göttingen. Institute of Microbiology and Genetics. Department of Genomic and Applied Microbiology (Germany)) ; Streit, Wolfgang R. (Universität Hamburg. Department of Microbiology and Biotechnology (Germany)) ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Stenotrophomonas maltophilia is one of the most frequently isolated multidrug-resistant nosocomial opportunistic pathogens. It contributes to disease progression in cystic fibrosis (CF) patients and is frequently isolated from wounds, infected tissues, and catheter surfaces. [...]
2020 - 10.1128/AEM.02038-20
Applied and Environmental Microbiology, Vol. 86, Issue 24 (December 2020) , art. e02038  
6.
12 p, 3.2 MB Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli / Rueda, Fabian (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Céspedes, María Virtudes (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez Chardi, Alejandro (Universitat Autònoma de Barcelona. Servei de Microscòpia) ; Seras-Franzoso, Joaquin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pesarrodona Roches, Mireia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ferrer-Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Helmholtz Centre for Infection Research) ; Unzueta Elorza, Ugutz (Institut d'Investigació Biomèdica Sant Pau) ; Mamat, Uwe (Airway Research Center North) ; Mangues, Ramon 1957- (Institut d'Investigació Biomèdica Sant Pau) ; Garcia-Fruitos, Elena (Institut de Recerca i Tecnologia Agroalimentàries) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Universitat Autònoma de Barcelona
Background: production of recombinant drugs in process-friendly endotoxin-free bacterial factories targets to a lessened complexity of the purification process combined with minimized biological hazards during product application. [...]
2016 - 10.1186/s12934-016-0457-z
Microbial cell factories, Vol. 15 (2016) , art. 59  
7.
17 p, 4.4 MB Complex Particulate Biomaterials as Immunostimulant-Delivery Platforms / Torrealba, Debora (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Seras-Franzoso, Joaquin (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Mamat, Uwe (Forschungszentrum Borstel. Division of Structural Biochemistry, Priority Area Asthma & Allergy) ; Wilke, Kathleen (Forschungszentrum Borstel. Division of Structural Biochemistry, Priority Area Asthma & Allergy) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Roher Armentia, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The control of infectious diseases is a major current challenge in intensive aquaculture. Most commercial vaccines are based on live attenuated or inactivated pathogens that are usually combined with adjuvants, oil emulsions being as the most widely used for vaccination in aquaculture. [...]
2016 - 10.1371/journal.pone.0164073
PloS one, Vol. 11 Issue 10 (Octubre 2016) , p. 1-17, art. e0164073  
8.
1 p, 682.3 KB Erratum to : Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins / Mamat, Uwe (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Wilke, Kathleen (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Bramhill, David (Bramhill Biological Consulting. East Moonstone Drive) ; Schromm, Andra Beate (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Lindner, Buko (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Kohl, Thomas Andreas (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Schaffer, Lana (The Scripps Research Institute) ; Head, Steven Robert (The Scripps Research Institute) ; Souvignier, Chad (Research Corporation Technologies (Tucson)) ; Meredith, Timothy Charles (Pennsylvania State University. Department of Biochemistry and Molecular Biology) ; Woodard, Ronald Wesley (University of Michigan. Department of Medicinal Chemistry)
2015 - 10.1186/s12934-015-0265-x
Microbial cell factories, Vol. 14, Issue 57 (2015)  
9.
15 p, 3.4 MB Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins / Mamat, Uwe (Forschungszentrum Borstel) ; Wilke, Kathleen (Forschungszentrum Borstel) ; Bramhill, David (Research Corporation Technologies (Tucson)) ; Schromm, Andra Beate (Forschungszentrum Borstel) ; Lindner, Buko (Forschungszentrum Borstel) ; Kohl, Thomas Andreas (Forschungszentrum Borstel) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Schaffer, Lana (Scripps Research Institute) ; Head, Steven Robert (Scripps Research Institute) ; Souvignier, Chad (Research Corporation Technologies (Tucson)) ; Meredith, Timothy Charles (Pennsylvania State University. Department of Biochemistry and Molecular Biology) ; Woodard, Ronald Wesley (Bramhill Biological Consulting)
Background: lipopolysaccharide (LPS), also referred to as endotoxin, is the major constituent of the outer leaflet of the outer membrane of virtually all Gram-negative bacteria. The lipid A moiety, which anchors the LPS molecule to the outer membrane, acts as a potent agonist for Toll-like receptor 4/myeloid differentiation factor 2-mediated pro-inflammatory activity in mammals and, thus, represents the endotoxic principle of LPS. [...]
2015 - 10.1186/s12934-015-0241-5
Microbial cell factories, Vol. 14, Issue 57 (2015)  
10.
18 p, 391.8 KB Production of functional inclusion bodies in endotoxin-free Escherichia coli / Rueda, Fabián (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cano-Garrido, Olivia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mamat, Uwe (Forschungszentrum Borstel) ; Wilke, Kathleen (Forschungszentrum Borstel) ; Seras-Franzoso, Joaquin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia-Fruitos, Elena (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Escherichia coli is the workhorse for gene cloning and production of soluble recombinant proteins in both biotechnological and biomedical industries. The bacterium is also a good producer of several classes of protein-based self-assembling materials such as inclusion bodies (IBs). [...]
2014 - 10.1007/s00253-014-6008-9
Applied microbiology and biotechnology, Vol. 98 issue 22 (Nov. 2014) , p. 9229-9238
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