Results overview: Found 4 records in 0.02 seconds.
Articles, 3 records found
Research literature, 1 records found
Articles 3 records found  
1.
12 p, 2.5 MB Liposome-based immunotherapy against autoimmune diseases : Therapeutic effect on multiple sclerosis / Pujol Autonell, Irma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mansilla López, Maria José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez Fernández, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cano Sarabia, Antonia María (Institut Català de Nanociència i Nanotecnologia) ; Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ampudia, Rosa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rius, Aleix (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García Jimeno, Sonia (Institut Català de Nanociència i Nanotecnologia) ; Perna Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Based on the ability of apoptosis to induce immunological tolerance, liposomes were generated mimicking apoptotic cells, and they arrest autoimmunity in Type 1 diabetes. Our aim was to validate the immunotherapy in other autoimmune disease: multiple sclerosis. [...]
2017 - 10.2217/nnm-2016-0410
Nanomedicine, Vol. 12, Issue 11 (June 2017) , p. 1231-1242  
2.
15 p, 2.0 MB Monitoring t-cell responses in translational studies: optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-specific responses / Brinke, Anja ten (Sanquin Research (Amsterdam)) ; Marek-Trzonkowska,Natalia (Medical University of Gdansk. Department of Family Medicine) ; Mansilla López, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Turksma, Annelies W. (Sanquin Research (Amsterdam)) ; Piekarska, Karolina (Medical University of Gdansk. Department of Family Medicine) ; Iwaszkiewicz-Grzes, Dorota (Medical University of Gdansk. Department of Clinical Immunology and Transplantology) ; Passerini, Laura (IRCCS San Raffaele Scientific Institute) ; Locafaro, Grazia (IRCCS San Raffaele Scientific Institute) ; Puñet Ortiz, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; van Ham, S. Marieke (Sanquin Research (Amsterdam)) ; Hernandez Fuentes, Maria P. (MRC Centre for Transplantation, King's College London) ; Martínez Cáceres, Eva M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gregori, Silvia (IRCCS San Raffaele Scientific Institute) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)- presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid organ and bone marrow transplantation. [...]
2017
Frontiers in immunology, Vol. 8 (december 2017) , p. 1-15  
3.
11 p, 1.5 MB Cryopreserved vitamin D3-tolerogenic dendritic cells pulsed with autoantigens as a potential therapy for multiple sclerosis patients / Mansilla López, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Contreras-Cardone, Raian (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cools, Nathalie (University of Antwerp. Vaccine & Infectious Disease Institute) ; Berneman,Zwi (University of Antwerp. Vaccine & Infectious Disease Institute) ; Ramo Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
BACKGROUND: Tolerogenic dendritic cells (tolDC) have been postulated as a potent immunoregulatory therapy for autoimmune diseases such as multiple sclerosis (MS). In a previous study, we demonstrated that the administration of antigen-specific vitamin D3 (vitD3) tolDC in mice showing clinical signs of experimental autoimmune encephalomyelitis (EAE; the animal model of MS) resulted in abrogation of disease progression. [...]
2016 - 10.1186/s12974-016-0584-9
Journal of Neuroinflammation, Vol. 13, No. 113 (May 2016)  

Research literature 1 records found  
1.
201 p, 5.6 MB Estudio de la función de la heat shock protein-70 en la patogenia de la esclerosis múltiple / Mansilla López, María José ; Espejo Ruiz, Carmen, dir. ; Montalban Gairin, Xavier, dir. ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
La proteína de choque térmico [heat shock protein (Hsp)-70] es una chaperona inducible por condiciones de estrés celular que puede ejercer una función citoprotectora y antiapoptótica a nivel intracelular, mientras que cuando es secretada al medio extracelular la Hsp70 actúa promoviendo la respuesta inmune, tanto la innata como la adaptativa. [...]
Heat shock protein (Hsp)-70 is a chaperone induced by cellular stress conditions which can mediate cytoprotective and antiapoptotic functions intracellularly, but when it is released to the extracellular milieu, Hsp70 acts triggering the immune response both innate and adaptive. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2015  

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