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9 p, 765.8 KB |
Mortality trends in type 1 diabetes : a multicountry analysis of six population-based cohorts
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Ruiz, P.L.D. (Diabetes and Population Health. Baker Heart and Diabetes Institute) ;
Chen, Lei (Baker Heart and Diabetes Institute) ;
Morton, J.I. (Monash University) ;
Salim, A. (The University of Melbourne) ;
Carstensen, B. (Steno Diabetes Center Copenhagen) ;
Gregg, E.W. (Imperial College London) ;
Pavkov, M.E. (Centers for Diseases Control and Prevention) ;
Mata-Cases, Manel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Nichols, G.A. (Kaiser Permanente Center for Health Research) ;
Pildava, S. (Centre for Disease Prevention and Control) ;
Read, S.H. (University of Edinburgh) ;
Wild, S.H. (University of Edinburgh) ;
Shaw, J.E. (La Trobe University) ;
Magliano, D.J. (Monash University) ;
Universitat Autònoma de Barcelona
Mortality has declined in people with type 1 diabetes in recent decades. We examined how the pattern of decline differs by country, age and sex, and how mortality trends in type 1 diabetes relate to trends in general population mortality. [...]
2022 -  10.1007/s00125-022-05659-9
Diabetologia, Vol. 65 Núm. 6 (june 2022) , p. 964-972
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8 p, 594.7 KB |
The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes : Achieving HbA1c targets with basal insulin in a real-world setting
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Meneghini, Luigi F. (Parkland Health & Hospital System) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Orsi, Emanuela (Fondazione Ca' Granda IRCCS) ;
Lalic, Nebojsa M. (University of Belgrade) ;
Cali, Anna M.G. (Sanofi) ;
Westerbacka, Jukka (Sanofi) ;
Stella, Peter (Sanofi) ;
Candelas, Christophe (Sanofi) ;
Pilorget, Valerie (Sanofi) ;
Perfetti, Riccardo (Sanofi) ;
Khunti, Kamlesh (University of Leicester) ;
Universitat Autònoma de Barcelona
To describe in a real-world setting the achievement of physician-selected individualized HbA1c targets in individuals with type 2 diabetes, newly or recently initiated with basal insulin, and the association of hypoglycaemia with target achievement. [...]
2019 - 10.1111/dom.13673
Diabetes, Obesity and Metabolism, Vol. 21 Núm. 6 (june 2019) , p. 1429-1436
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13 p, 266.5 KB |
Poorer quality of life and treatment satisfaction is associated with diabetic retinopathy in patients with type 1 diabetes without other advanced late complications
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Granado-Casas, Minerva (Institut d'Investigació Biomèdica Sant Pau) ;
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez-Morros, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martín, Mariona (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alcubierre, Nuria (Universitat de Lleida) ;
Martínez-Alonso, M. (Institut de Recerca Biomèdica de Lleida) ;
Valldeperas, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Traveset, A. (Hospital Universitari Arnau de Vilanova) ;
Rubinat, Esther (Universitat de Lleida) ;
Lucas-Martin, Ana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Hernández, Marta (Hospital Universitari Arnau de Vilanova) ;
Alonso Pedrol, Núria (Instituto de Salud Carlos III) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Diabetic retinopathy (DR) may potentially cause vision loss and affect the patient's quality of life (QoL) and treatment satisfaction (TS). Using specific tools, we aimed to assess the impact of DR and clinical factors on the QoL and TS in patients with type 1 diabetes. [...]
2019 - 10.3390/jcm8030377
Journal of clinical medicine, Vol. 8 Núm. 3 (march 2019) , p. 377
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14 p, 1.7 MB |
Circulating soluble CD36 is similar in type 1 and type 2 diabetes mellitus versus non-diabetic subjects
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Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Sanjurjo, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Falguera, Mireia (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Hernández, Marta (Hospital Universitari Arnau de Vilanova) ;
Fernandez-Real, J.M. (Hospital Universitari de Girona Doctor Josep Trueta) ;
Sarrias, Maria-Rosa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The aim of this study was to determine whether plasma concentrations of sCD36 (soluble CD36) are associated with the presence of type 1 or type 2 diabetes. Plasma levels of sCD36 were analysed in 1023 subjects (225 type 1 diabetes (T1D) patients, 276 type 2 diabetes (T2D) patients, and 522 non-diabetic control subjects) using an enzyme-linked immunosorbent assay (ELISA). [...]
2019 - 10.3390/jcm8050710
Journal of clinical medicine, Vol. 8 Núm. 5 (may 2019) , p. 710
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11 p, 284.2 KB |
Prediabetes is independently associated with subclinical carotid atherosclerosis : An observational study in a non-urban mediterranean population
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Vilanova, Maria Belén (Universitat de Lleida) ;
Franch-Nadal, Josep (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Falguera, Mireia (Institut Català de la Salut) ;
Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron) ;
Canivell, S. (Institut Català de la Salut) ;
Rubinat, Esther (Institut de Recerca Biomèdica de Lleida) ;
Miró, Neus (Institut Català de la Salut) ;
Molló, Àngels (Institut Català de la Salut) ;
Mata-Cases, Manel (Institut Català de la Salut) ;
Gratacòs, Mònica (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
This was a prospective, observational study to compare the burden of subclinical atherosclerosis as measured by carotid ultrasonography in a cohort of subjects with prediabetes vs. subjects with normal glucose tolerance (NGT) from a non-urban Mediterranean population. [...]
2020 - 10.3390/jcm9072139
Journal of clinical medicine, Vol. 9 Núm. 7 (july 2020) , p. 1-11
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12 p, 1.0 MB |
The importance of the initial period of basal insulin titration in people with diabetes
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Khunti, Kamlesh (University of Leicester) ;
Giorgino, F. (University of Bari Aldo Moro) ;
Berard, L. (Winnipeg Regional Health Authority) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Harris, S.B. (Western University) ;
Universitat Autònoma de Barcelona
Achieving target glycaemic control is essential in people with diabetes to minimize the risk of long-term complications, and many people with type 2 diabetes will ultimately require basal insulin (BI) therapy to achieve their individualized glycaemic targets. [...]
2020 - 10.1111/dom.13946
Diabetes, Obesity and Metabolism, Vol. 22 Núm. 5 (january 2020) , p. 722-733
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9 p, 1.0 MB |
Prevalence of pre-diabetes and undiagnosed diabetes in the Mollerussa prospective observational cohort study in a semi-rural area of Catalonia
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Falguera, M. (Universitat de Lleida) ;
Vilanova, M.B. (Universitat de Lleida) ;
Alcubierre, Nuria (Avantmedic (Lleida)) ;
Granado-Casas, Minerva (Institut d'Investigació Biomèdica Sant Pau) ;
Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron) ;
Miró, N. (Institut Català de la Salut) ;
Cebrian, C. (Institut Català de la Salut) ;
Molló, À. (Institut Català de la Salut) ;
Franch-Nadal, J. (Institut Català de la Salut) ;
Mata-Cases, Manel (Institut Català de la Salut) ;
Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
To assess the prevalence of undiagnosed diabetes and pre-diabetes in the healthy population in the Mollerussa cohort. As a secondary objective, to identify the variables associated with these conditions and to describe the changes in glycaemic status after 1 year of follow-up in subjects with pre-diabetes. [...]
2020 - 10.1136/bmjopen-2019-033332
BMJ open, Vol. 10 Núm. 1 (20 2020) , p. 33332
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13 p, 1.6 MB |
Real-world outcomes of treatment with insulin glargine 300 U/mL versus standard-of-care in people with uncontrolled type 2 diabetes mellitus
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Freemantle, Nick (University College London) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Giaccari, A. (Università Cattolica del Sacro Cuore) ;
Bailey, T. (AMCR Institute) ;
Roussel, R. (UFR de Médecine. Paris University) ;
Franco, D. (CPCLIN Clinical Research Center) ;
Berthou, B. (IT&M Stats) ;
Pilorget, V. (Sanofi) ;
Westerbacka, J. (Sanofi) ;
Bosnyak, Z. (Sanofi) ;
Bonnemaire, Mireille (Sanofi) ;
Cali, Anna M.G (Sanofi) ;
Nguyên-Pascal, M.L. (Sanofi) ;
Penfornis, A. (Corbeil-Essonnes and Université Paris Sud) ;
Perez-Maraver, Manuel (Hospital Universitari de Bellvitge) ;
Seufert, J. (University of Freiburg) ;
Sullivan, S.D. (University of Washington) ;
Wilding, J. (University of Liverpool) ;
Wysham, C. (Multicare Rockwood Clinic) ;
Davies, M. (University of Leicester) ;
Universitat Autònoma de Barcelona
To compare real-world outcomes with newer (insulin glargine 300 U/mL; Gla-300) versus standard of care (SoC) basal insulins (BIs) in the REACH (insulin-naïve; NCT02967224) and REGAIN (basal insulin-treated; NCT02967211) studies in participants with uncontrolled type 2 diabetes (T2DM) in Europe and Brazil. [...]
2020 - 10.1080/03007995.2019.1708287
Current Medical Research and Opinion, Vol. 36 Núm. 4 (february 2020) , p. 571-581
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8 p, 533.2 KB |
Rationale and methodology for a European pooled analysis of postmarketing interventional and observational studies of insulin glargine 300 U/mL in diabetes : Protocol of REALI project
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Freemantle, N. (University College London) ;
Bonadonna, Riccardo C (University of Parma) ;
Gourdy, P. (Paul Sabatier University) ;
Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ;
Mueller-Wieland, D. (University Hospital Aachen (Alemanya)) ;
Bigot, Gregory (IVIDATA) ;
Ciocca, A. (Sanofi SA) ;
Mauquoi, C. (IDDI SA) ;
Rollot, M. (Quinten) ;
Bonnemaire, Mireille (Sanofi SA) ;
Universitat Autònoma de Barcelona
Type 2 diabetes mellitus (T2DM) is a common and heterogeneous disease. Using advanced analytic approaches to explore real-world data may identify different disease characteristics, responses to treatment and progression patterns. [...]
2020 - 10.1136/bmjopen-2019-033659
BMJ open, Vol. 10 Núm. 4 (28 2020) , p. 201903365
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