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6 p, 5.8 MB Centrality in the host-pathogen interactome is associated with pathogen fitness during infection / Crua Asensio, Núria (Hospital Universitari Vall d'Hebron) ; Muñoz Giner, Elisabet (Hospital Universitari Vall d'Hebron) ; Sánchez de Groot, Natalia (Universitat Pompeu Fabra) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
To perform their functions proteins must interact with each other, but how these interactions influence bacterial infection remains elusive. Here we demonstrate that connectivity in the host-pathogen interactome is directly related to pathogen fitness during infection. [...]
2017 - 10.1038/ncomms14092
Nature communications, Vol. 8 (January 2017) , art. 14092  

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