Results overview: Found 9 records in 0.02 seconds.
Articles, 5 records found
Research literature, 4 records found
Articles 5 records found  
1.
Nano-scavengers for blood biomarker discovery in ovarian carcinoma / Hadjidemetriou, Marilena (The University of Manchester. Nanomedicine Lab) ; Papafilippou, Lana (The University of Manchester. Nanomedicine Lab) ; Unwin, Richard D. (The University of Manchester. Division of Cardiovascular Sciences) ; Rogan, Jane (Manchester Cancer Research Centre Biobank) ; Clamp, Andrew (The University of Manchester. Manchester Cancer Research Centre) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
The development and implementation of biomarker-based screening tools for ovarian cancer require novel analytical platforms to enable the discovery of biomarker panels that will overcome the limitations associated with the clinically used CA-125. [...]
2020 - 10.1016/j.nantod.2020.100901
Nano Today, Vol. 34 (Oct. 2020) , art. 100901  
2.
18 p, 288.5 KB Translational research opportunities regarding homologous recombination in ovarian cancer / Romeo Marín, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pardo, J.C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Quiroga, Vanesa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Román, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Solé, Francesc (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Homologous recombination (HR) is a DNA repair pathway that is deficient in 50% of high-grade serous ovarian carcinomas (HGSOC). Deficient HR (DHR) constitutes a therapeutic opportunity for these patients, thanks to poly (ADP-ribose) polymerases (PARP) inhibitors (PARPi; olaparib, niraparib, and rucaparib are already commercialized). [...]
2018 - 10.3390/ijms19103249
International journal of molecular sciences, Vol. 19 Núm. 10 (19 2018) , p. 3249  
3.
13 p, 2.3 MB The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients / Gayarre, Javier (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ; Kamieniak, Marta M. (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ; Cazorla-Jiménez, Alicia (Department of Pathology, Fundación Jiménez Díaz-IDC Salud) ; Muñoz-Repeto, Ivan (Human Genetics Group, Spanish National Cancer Research Center (CNIO)) ; Borrego, Salud (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ; García-Donas, Jesús (Medical Oncology Service, Oncologic Center Clara Campal) ; Hernando, Susana (Department of Oncology, Fundación Hospital Alcorcón) ; Robles-Díaz, Luis (Familial Cancer Unit and Medical Oncology Department, Hospital 12 de Octubre) ; García-Bueno, José M. (Department of Oncology, Hospital General de Albacete) ; Ramón y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ; Hernández-Agudo, Elena (Breast Cancer Clinical Research Unit, Spanish National Cancer Research Center (CNIO)) ; Heredia Soto, Victoria (Pathology and Translational Oncology Research Laboratories, Hospital La Paz Institute for Health Research (IdiPAZ)) ; Márquez-Rodas, Ivan (Medical Oncology Service, Instituto de Investigación Sanitaria Gregorio Marañón, Universidad Complutense) ; Echarri, María José (Medical Oncology Service, Hospital Severo Ochoa) ; Lacambra-Calvet, Carmen (Department of Internal Medicine, Hospital Severo Ochoa) ; Sáez, Raquel (Laboratory of Genetics, Hospital Donostia) ; Cusidó, Maite (Department of Obstetrics and Gynecology, Hospital Universitario Quirón-Dexeus) ; Redondo, Andrés (Department of Medical Oncology, Hospital La Paz IdiPAZ, Madrid) ; Paz-Ares, Luis (Medical Oncology Service, Hospital 12 de Octubre) ; Hardisson, David (Pathology Research Laboratory, Department of Pathology, Hospital La Paz IdiPAZ, and Facultad de Medicina, Universidad Autónoma de Madrid) ; Mendiola, Marta (Pathology and Translational Oncology Research Laboratories, Hospital La Paz Institute for Health Research (IdiPAZ)) ; Palacios, José (Department of Pathology, Hospital Universitario Ramón y Cajal) ; Benítez, Javier (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ; García, María José (Biomedical Network Research Centre on Rare Diseases (CIBERER)) ; Universitat Autònoma de Barcelona. Departament de Medicina
We aimed to evaluate the prognostic and predictive value of the nucleotide excision repair-related gene GTF2H5, which is localized at the 6q24. 2-26 deletion previously reported by our group to predict longer survival of high-grade serous ovarian cancer patients. [...]
2015 - 10.3802/jgo.2016.27.e7
Journal of Gynecologic Oncology, Vol. 27 (november 2015)  
4.
7 p, 662.6 KB Random-start GnRH antagonist for emergency fertility preservation : a self-controlled trial / Checa, Miguel Angel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetricia i Ginecologia i Medicina Preventiva) ; Brassesco, Mario (Centro de Infertilidad y Reproducción Humana) ; Sastre, Margalida (Parc de Salut Mar. Departament d'Obstetrícia i Ginecologia) ; Gómez, Manuel (Centro de Infertilidad y Reproducción Humana) ; Herrero García, Julio (Centro de Reproducción Asistida Sagrada Familia, Clínica Sagrada Familia) ; Marque, Laura (Centro de Reproducción Asistida Sagrada Familia, Clínica Sagrada Familia) ; Brassesco, Arturo (Centro de Infertilidad y Reproducción Humana) ; Espinós, Juan José (Centro de Reproducción Asistida Sagrada Familia, Clínica Sagrada Familia)
The aim of this study is to evaluate the feasibility and safety of random-start controlled ovarian hyperstimulation (COH) for emergency fertility preservation, regardless of the phase of the menstrual cycle. [...]
2015 - 10.2147/IJWH.S66743
International Journal of Women's Health, Vol. 7 (february 2015) , p. 219-225  
5.
15 p, 3.0 MB Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer / Alonso, Sergio (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; González, Beatriz (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Ruiz-Larroya, Tatiana (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Durán Domínguez, Mercedes (Instituto de Biología y Genética Molecular (Valladolid)) ; Kato, Takaharu (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Matsunaga, Akihiro (Sanford Burnham Prebys Medical Discovery Institute (Califòrnia)) ; Suzuki, Koichi (Jichi Medical University (Japó)) ; Strongin, Alex Y. (Sanford Burnham Prebys Medical Discovery Institute (Califòrnia)) ; Giménez Bonafé, Pepita (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Perucho, Manuel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer)
BACKGROUND: ADAMTS19 encodes a member of the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) protein family with emerging roles in carcinogenesis and metastasis. ADAMTS shares several distinct protein modules including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. [...]
2015 - 10.1186/s13148-015-0158-1
Clinical Epigenetics, Vol. 7, No. 124 (December 2015)  

Research literature 4 records found  
1.
1 p, 532.1 KB Telomeres and telomerase in ovarian cancer / Planas Riverola, Ainoa ; Tusell Padrós, Laura, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Universitat Autònoma de Barcelona. Facultat de Biociències
Ovarian cancer is the 6th most frequent and the most lethal of the gynaecological cancer; is its oestrogen dependent and it is associated with mutations in BRCA1 and BRCA2 genes. Both oestrogens and progesterone, and BRCA1 gene have important roles in the regulation of telomerase and telomeres, key structures in development and in progress in every epithelial cancer.
2015
Grau en Genètica [833]  
2.
1 p, 2.0 MB New biomarkers for early detection of ovarian cancer / Roman i Canal, Berta ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Ciències Biomèdiques [832]  
3.
1 p, 689.8 KB HE4 as biomarker for ovarian cancer : a critical review / Pagès Martínez, Ernest ; Blanco Vaca, Francisco, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2014
Grau en Bioquímica [814]  
4.
1 p, 843.1 KB Chemoresistance to paclitaxel induces EMT in different types of ovarian carcinoma tumors / Martínez Marchal, Ana ; Itarte, Emilio, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Universitat Autònoma de Barcelona. Facultat de Biociències
2013
Grau en Biologia [812]  

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