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20 p, 10.3 MB |
The ERK5/NF-κB signaling pathway targets endometrial cancer proliferation and survival
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Diéguez-Martínez, Nora (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Espinosa-Gil, Sergio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Yoldi Salinas, Guillermo (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Megías-Roda, Elisabet (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bolinaga-Ayala, Idoia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Viñas-Casas, Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Gorgisen, Gokhan (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Domingo-Ortí, Inés (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Pérez-Montoyo, Héctor (Ability Pharmaceuticals (Cerdanyola del Vallès)) ;
Bayascas Ramírez, José Ramón (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Dolcet, Xavier (Universitat de Lleida) ;
Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Endometrial cancer (EC) is the most common type of gynecologic cancer in women of developed countries. Despite surgery combined with chemo-/radiotherapy regimens, overall survival of patients with high-risk EC tumors is poor, indicating a need for novel therapies. [...]
2022 -  10.1007/s00018-022-04541-6
Cellular and Molecular Life Sciences, Vol. 79 (2022) , p. 524
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2.
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10 p, 1.7 MB |
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis
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París-Coderch, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jiménez Jiménez, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Erazo, Tatiana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Muñoz-Guardiola, Pau (Ability Pharmaceuticals) ;
Masanas, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Antonelli, Roberta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Boloix, Ariadna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alfón, José (Ability Pharmaceuticals) ;
Pérez-Montoyo, Héctor (Ability Pharmaceuticals) ;
Yeste-Velasco, Marc (Ability Pharmaceuticals) ;
Domènech, Carles (Ability Pharmaceuticals) ;
Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez de Toledo Codin, Josep (Vall d'Hebron Institut d'Oncologia) ;
Moreno, Lucas (Vall d'Hebron Institut d'Oncologia) ;
Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Gallego, Soledad (Vall d'Hebron Institut d'Oncologia) ;
Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Neuroblastoma is the leading cause of cancer death in children aged 1 to 4 years. Particularly, five-year overall survival for high-risk neuroblastoma is below 50% with no curative options when refractory or relapsed. [...]
2020 - 10.1038/s41419-020-02986-w
Cell death and disease, Vol. 11 (september 2020)
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18 p, 5.4 MB |
Tween 80 Improves the Acid-Fast Bacilli Quantification in the Magnetic Nanoparticle-Based Colorimetric Biosensing Assay (NCBA)
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Gordillo-Marroquín, Cristina (Social Observatory of Tuberculosis Mexico, El Colegio de La Frontera Sur (ECOSUR)) ;
Sánchez-Pérez, Héctor J. (Social Observatory of Tuberculosis Mexico, El Colegio de La Frontera Sur (ECOSUR)) ;
Gómez-Velasco, Anaximandro (Department of Human Ecology, Center for Research and Advanced Studies of the National Polytechnic Institute (Cinvestav-IPN)) ;
Martín Mateo, Miguel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Guillén-Navarro, Karina (Sustainability Sciences Department, El Colegio de la Frontera Sur (ECOSUR)) ;
Vázquez-Marcelín, Janeth (Mycobacteriology Laboratory, TB Prevention and Control Program for the Highlands of Chiapas, Ministry of Health of Chiapas) ;
Gómez-Bustamante, Adriana (State Public Health Laboratory for Chiapas, Ministry of Health of Chiapas) ;
Jonapá-Gómez, Letisia (State Public Health Laboratory for Chiapas, Ministry of Health of Chiapas) ;
Alocilja, Evangelyn C. (Nano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University)
Despite its reduced sensitivity, sputum smear microscopy (SSM) remains the main diagnostic test for detecting tuberculosis in many parts of the world. A new diagnostic technique, the magnetic nanoparticle-based colorimetric biosensing assay (NCBA) was optimized by evaluating different concentrations of glycan-functionalized magnetic nanoparticles (GMNP) and Tween 80 to improve the acid-fast bacilli (AFB) count. [...]
2022 - 10.3390/bios12010029
Biosensors, Vol. 12 Num. 1(january 2022)
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13 p, 1.5 MB |
Magnetic Nanoparticle-Based Biosensing Assay Quantitatively Enhances Acid-Fast Bacilli Count in Paucibacillary Pulmonary Tuberculosis
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Gordillo-Marroquín, Cristina (Global Alliance for Rapid Diagnostics. Michigan State University) ;
Gómez-Velasco, Anaximandro (Global Alliance for Rapid Diagnostics. Michigan State University) ;
Sánchez-Pérez, Héctor J. (Global Alliance for Rapid Diagnostics. Michigan State University) ;
Pryg, Kasey (Nano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University) ;
Shinners, John (Nano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University) ;
Murray, Nathan (Nano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University) ;
Muñoz-Jiménez, Sergio G. (Mycobacteriology Laboratory, TB Prevention and Control Program for the Highlands of Chiapas, Mexico) ;
Bencomo-Alerm, Allied (Mycobacteriology Laboratory, TB Prevention and Control Program for the Highlands of Chiapas, Mexico) ;
Gómez-Bustamante, Adriana (State Public Health Laboratory for Chiapas, Tuxtla Gutierrez, Chiapas Mexico) ;
Jonapá-Gómez, Letisia (State Public Health Laboratory for Chiapas, Tuxtla Gutierrez, Chiapas, Mexico) ;
Enríquez-Ríos, Natán (Communicable and Non-communicable Diseases Department, Ministry of Health of Chiapas, Tuxtla Gutierrez, Chiapas, Mexico) ;
Martín Mateo, Miguel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Romero-Sandoval, Natalia (Faculty of Medical Sciences, and Health and Life, International University of Ecuador, Quito) ;
Alocilja, Evangelyn C. (Nano-Biosensors Laboratory, Department of Biosystems and Agricultural Engineering, Michigan State University)
2018 - 10.3390/bios8040128
Biosensors, Vol. 8 (december 2018)
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12 p, 2.5 MB |
Cancer network activity associated with therapeutic response and synergism
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Serra-Musach, Jordi (Institut Català d'Oncologia) ;
Mateo, Francesca (Institut Català d'Oncologia) ;
Capdevila-Busquets, Eva (Institut de Recerca Biomèdica de Lleida) ;
de Garibay, Gorka Ruiz (Institut Català d'Oncologia) ;
Zhang, Xiaohu (National Center for Advancing Translational Sciences (Bethesda, Estats Units d'Amèrica)) ;
Guha, Raj (National Center for Advancing Translational Sciences (Bethesda, Estats Units d'Amèrica)) ;
Thomas, Craig J. (National Center for Advancing Translational Sciences (Bethesda, Estats Units d'Amèrica)) ;
Grueso, Judit (Vall d'Hebron Institut d'Oncologia) ;
Villanueva, Alberto (Institut Català d'Oncologia) ;
Jaeger, Samira (Institut de Recerca Biomèdica de Lleida) ;
Heyn, Holger (Institut d'Investigació Biomèdica de Bellvitge) ;
Vizoso, Miguel (Institut d'Investigació Biomèdica de Bellvitge) ;
Pérez Montero, Hector (Institut d'Investigació Biomèdica de Bellvitge) ;
Cordero, Alex (Institut d'Investigació Biomèdica de Bellvitge) ;
González Suarez, Eva (Institut d'Investigació Biomèdica de Bellvitge) ;
Esteller, M. (Institució Catalana de Recerca i Estudis Avançats) ;
Moreno-Bueno, Gema (Universidad Autónoma de Madrid. Departamento de Bioquímica) ;
Tjärnberg, Andreas (Linköping University. Departament of Clinical and Experimental Medicine) ;
Lázaro, Conxi (Institut Català d'Oncologia) ;
Serra, Violeta (Vall d'Hebron Institut d'Oncologia) ;
Arribas, Joaquín V. (Vicente) (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Benson, Mikael (Linköping University. Department of Clinical and Experimental Medicine) ;
Gustafsson, Mika (Linköping University. Department of Clinical and Experimental Medicine) ;
Ferrer, Marc (National Center for Advancing Translational Sciences (Bethesda, Estats Units d'Amèrica)) ;
Aloy, Patrick (Institució Catalana de Recerca i Estudis Avançats) ;
Pujana, Miquel Àngel (Institut Català d'Oncologia)
Cancer patients often show no or only modest benefit from a given therapy. This major problem in oncology is generally attributed to the lack of specific predictive biomarkers, yet a global measure of cancer cell activity may support a comprehensive mechanistic understanding of therapy efficacy. [...]
2016 - 10.1186/s13073-016-0340-x
Genome Medicine, Vol. 8 (August 2016) , ART. 88
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3 p, 128.8 KB |
Public transportation and pulmonary Tuberculosis, Lima, Peru
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Horna Campos, Olivia Janett (Universitat Autònoma de Barcelona) ;
Sánchez Pérez, Héctor Javier (El Colegio de la Frontera Sur (San Cristóbal de las Casas, Mèxic)) ;
Sánchez, Inma (Universitat Autònoma de Barcelona) ;
Bedoya, Alfredo (Dirección de Salud IV Lima Este (Lima, Perú)) ;
Martín Mateo, Miguel (Universitat Autònoma de Barcelona)
The association between public transportation for commuting and pulmonary tuberculosis (TB) was analyzed in workers in Lima, Peru. Traveling in minibuses was a risk factor for pulmonary TB. Preventive measures need to be taken by health services to prevent spread of this disease.
2007 - 10.3201/eid1310.060793
Emerging Infectious Diseases, Vol. 13, Num. 10 (October 2007) , p. 1491-1493
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12 p, 213.5 KB |
Algunos problemas en la enseñanza de la relatividad
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Pérez, Héctor (IES de Sedaví (València)) ;
Solbes Matarredona, Jordi (IES J. Rodrigo Botet (Manises))
La relatividad es una parte importante de la física moderna. En este artículo se analiza su enseñanza-aprendizaje en la enseñanza secundaria y se muestran sus principales dificultades. El artículo argumenta razonadamente contra prácticas tradicionales en la enseñanza de la relatividad y finalmente apunta una nueva aproximación a su enseñanza.
Relativity is a very important part of modern physics. In this paper we analyze the teaching and learning of the theory of relativity at secondary school level and we show the pupils' main difficulties. [...]
2003 - 10.5565/rev/ensciencias.3947
Enseñanza de las ciencias, V. 21 N. 1 (2003) , p. 135-146
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