Results overview: Found 12 records in 0.02 seconds.
Articles, 8 records found
Research literature, 4 records found
Articles 8 records found  
1.
14 p, 954.2 KB Plasma HIV-1 Tropism and the Risk of Short- Term Clinical Progression to AIDS or Death / Casadellà, Maria (Institut Germans Trias i Pujol. IrsiCaixa) ; Cozzi-Lepri, Alessandro (Royal Free Hospital, London) ; Phillips, Andrew (Royal Free Hospital, London) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Bickel, Markus (Goethe University) ; Sedlacek, Dalibor (Charles University Hospital, Plzen, Česka ́Republika) ; Zilmer, Kai (West-Tallinn Central Hospital, Tallinn,) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. IrsiCaixa) ; Lundgren, Jens D. (CHIP, Department of Infectious Diseases, Rigshospitalet, University of Copenhagen) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa) ; EuroSIDA in EuroCOORD ; Universitat Autònoma de Barcelona
Objective. To investigate if plasma HIV-1 tropism testing could identify subjects at higher risk for clinical progression and death in routine clinical management. Design. Nested case-control study within the EuroSIDA cohort. [...]
2017
Plos one, 2017, p. 1-14  
2.
9 p, 820.3 KB Oral microbiome in HIV-associated periodontitis / Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Guillén Montalbán, Yolanda (Universitat Autònoma de Barcelona) ; Peterson, Jessica (Emory University. School of Medicine. Division of Infectious Diseases) ; Reznik, David (Emory University. School of Medicine. Division of Infectious Diseases) ; Harris, Erica V. (Emory University. Department of Biology) ; Joseph, Sandeep J. (Emory University. School of Medicine. Division of Infectious Diseases) ; Rivera, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Kannanganat, Sunil (Emory University. School of Medicine. Division of Infectious Diseases) ; Amara, Rama (Emory University. School of Medicine. Division of Infectious Diseases) ; Nguyen, Minh Ly (Emory University. School of Medicine. Division of Infectious Diseases) ; Mutembo, Simon (Zàmbia. Ministry of Health) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Read, Timothy D. (Emory University. School of Medicine. Division of Infectious Diseases) ; Marconi, Vincent C. (Emory University. School of Medicine. Division of Infectious Diseases)
Supplemental Digital Content is available in the text HIV-associated periodontal diseases (PD) could serve as a source of chronic inflammation. Here, we sought to characterize the oral microbial signatures of HIV+ and HIV– individuals at different levels of PD severity. [...]
2017 - 10.1097/MD.0000000000005821
Medicine, Vol. 96, issue 12 (March 2017) , e5821  
3.
15 p, 4.1 MB Lack of concordance between residual viremia and viral variants driving de novo infection of CD4 + T cells on ART / Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Noguera-Julian, Marc (Universitat de Vic – Universitat Central de Catalunya (UVic-UCC), Vic, Spain) ; Massanella, Marta (Département de Microbiologie, Infectiologie et Immunologie, Centre de Recherche du CHUM et Université de Montréal) ; Pou, Christian (Department of Cell and Molecular Biology, Karolinska Institutet, Solna, Stockholm Sweden) ; Buzón, María José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Clotet, Bonaventura (Universitat de Vic – Universitat Central de Catalunya (UVic-UCC), Vic, Spain) ; Stevenson, Mario (Division of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, USA) ; Paredes, Roger (Universitat de Vic – Universitat Central de Catalunya (UVic-UCC), Vic, Spain) ; Blanco, Julià (Universitat de Vic – Universitat Central de Catalunya (UVic-UCC), Vic, Spain) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats (ICREA))
In most patients, current antiretroviral therapy (ART) regimens can rapidly reduce plasma viral load. However, even after years of effective treatment, a significant proportion of patients show residual plasma viremia below the clinical detection limit. [...]
2016 - 10.1186/s12977-016-0282-9
Retrovirology, Vol. 13 (august 2016)  
4.
6 p, 177.5 KB HIV-1 drug resistance by ultra-deep sequencing following short course zidovudine, single-dose nevirapine, and single-dose tenofovir with emtricitabine for prevention of mother-to-child transmission / Samuel, Reshmi (University of KwaZulu-Natal. Department of Virology) ; Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa) ; Parboosing, Raveen (University of KwaZulu-Natal. Department of Virology) ; Moodley, Pravi (University of KwaZulu-Natal. Department of Virology) ; Singh, Lavanya (University of KwaZulu-Natal. Department of Virology) ; Naidoo, Anneta (University of KwaZulu-Natal. Department of Virology) ; Gordon, Michelle (University of KwaZulu-Natal. Department of Virology) ; Universitat Autonoma de Barcelona
Antiretroviral drug resistance following pMTCT strategies remains a significant problem. With rapid advancements in next generation sequencing technologies, there is more focus on HIV drug-resistant variants of low frequency, or the so-called minority variants. [...]
2016 - 10.1097/QAI.0000000000001116
Journal of acquired immune deficiency syndromes (1999), Vol. 73, issue 4 (Dec. 2016) , p. 384-389  
5.
12 p, 2.8 MB Gut microbiota linked to sexual preference and HIV infection / Noguera-Julian, Marc (Institut Germans Trias i Pujol. IrsiCaixa) ; Rocafort, Muntsa (Institut Germans Trias i Pujol. IrsiCaixa) ; Guillén, Yolanda (Institut Germans Trias i Pujol. IrsiCaixa) ; Rivera, Javier (Institut Germans Trias i Pujol. IrsiCaixa) ; Casadellà, Maria (Institut Germans Trias i Pujol. IrsiCaixa) ; Nowak, Piotr (Karolinska Universitetssjukhuset) ; Hildebrand, Falk (European Molecular Biology Laboratory) ; Zeller, Georg (European Molecular Biology Laboratory) ; Parera, Mariona (Institut Germans Trias i Pujol. IrsiCaixa) ; Bellido, Rocío (Institut Germans Trias i Pujol. IrsiCaixa) ; Rodríguez, Cristina (Institut Germans Trias i Pujol. IrsiCaixa) ; Carrillo, Jorge (Institut Germans Trias i Pujol. IrsiCaixa) ; Mothe, Beatriz (Institut Germans Trias i Pujol. IrsiCaixa) ; Coll, Josep (Institut Germans Trias i Pujol. IrsiCaixa) ; Bravo, Isabel (Hospital Universitari Germans Trias i Pujol) ; Estany, Carla (Hospital Universitari Germans Trias i Pujol) ; Herrero, Cristina (Hospital Universitari Germans Trias i Pujol) ; Saz, Jorge (BCN Checkpoint,) ; Sirera, Guillem (Hospital Universitari Germans Trias i Pujol) ; Torrela, Ariadna (Hospital Universitari Vall d'Hebrón) ; Navarro, Jordi (Hospital Universitari Vall d'Hebrón) ; Crespo, Manel (Hospital Universitari Vall d'Hebrón) ; Brander, Christian (Institut Germans Trias i Pujol. IrsiCaixa) ; Negredo, Eugènia (Universitat de Vic) ; Blanco, Julià (Institut Germans Trias i Pujol. IrsiCaixa) ; Guarner, Francisco (Hospital Universitari Vall d'Hebrón) ; Calle, Maria Luz (Universitat de Vic) ; Bork, Peer (European Molecular Biology Laboratory) ; Sönnerborg, Anders (Karolinska Universitetssjukhuset) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. IrsiCaixa)
The precise effects of HIV-1 on the gut microbiome are unclear. Initial cross-sectional studies provided contradictory associations between microbial richness and HIV serostatus and suggested shifts from Bacteroides to Prevotella predominance following HIV-1 infection, which have not been found in animal models or in studies matched for HIV-1 transmission groups. [...]
2016 - 10.1016/j.ebiom.2016.01.032
EBioMedicine, Vol. 5 (March 2016) , p. 135-146  
6.
11 p, 203.3 KB Mutations related to Antiretroviral Resistance identified by ultra-deep sequencing in HIV-1 infected children under Structured Interruptions of HAART / Vázquez Guillén, José Manuel (Universidad Autónoma de Nuevo León (Mèxic)) ; Palacios Saucedo, Gerardo C. (Instituto Mexicano del Seguro Social) ; Rivera Morales, Lydia G. (Universidad Autónoma de Nuevo León (Mèxic)) ; García Campos, Jorge (Instituto Mexicano del Seguro Social) ; Ortiz López, Rocío (Universidad Autónoma de Nuevo León (Mèxic)) ; Noguera Julián, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vielma Ramírez, Herlinda J. (Universidad Autónoma de Nuevo León (Mèxic)) ; Ramírez, Teresa (Laboratorio Estatal de Salud Pública del Estado de Nuevo León (Mèxic)) ; Chávez García, Marcelino (Instituto Mexicano del Seguro Social) ; López Guillén, Paulo (Instituto Mexicano del Seguro Social) ; Briones Lara, Evangelina (Instituto Mexicano del Seguro Social) ; Sánchez Sánchez, Luz M. (Instituto Mexicano del Seguro Social) ; Vázquez Martínez, Carlos A. (Instituto Mexicano del Seguro Social) ; Rodríguez Padilla, Cristina (Universidad Autónoma de Nuevo León (Mèxic))
Although Structured Treatment Interruptions (STI) are currently not considered an alternative strategy for antiretroviral treatment, their true benefits and limitations have not been fully established. [...]
2016 - 10.1371/journal.pone.0147591
PloS one, Vol. 11 Núm. 1 (January 2016)  
7.
17 p, 2.2 MB A Follow-Up of the Multicenter Collaborative Study on HIV-1 Drug Resistance and Tropism Testing Using 454 Ultra Deep Pyrosequencing / Saint John, Elizabeth P. (454 Life Sciences (Brandford, Estats Units d'Amèrica)) ; Simen, Birgitte B. (454 Life Sciences (Brandford, Estats Units d'Amèrica)) ; Turenchalk, Gregory S. (454 Life Sciences (Brandford, Estats Units d'Amèrica)) ; Braverman, Michael S. (454 Life Sciences (Brandford, Estats Units d'Amèrica)) ; Abbate, Isabella (National Institute for Infectious Diseases (Roma, Itàlia)) ; Aerssens, Jeroen (Janssen Infectious Diseases (Beerse, Bèlgica)) ; Bouchez, Olivier (Plateforme Génomique Toulouse/Laboratoire Génétique Cellulaire (Toulouse, França)) ; Gabriel, Christian (Blutzentrale Linz (Àustria)) ; Izopet, Jacques (INSERM U56 (Toulouse, França)) ; Meixenberger, Karolin (Robert Koch-Institute (Berlin, Alemanya)) ; Di Giallonardo, Francesca (University of Zurich) ; Schlapbach, Ralph (University of Zurich) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Sakwa, James (Technology Innovation Agency-National Genomics Platform (Durban, Sud-àfrica)) ; Schmitz-Agheguian, Gudrun G. (Roche Applied Science (Penzberg, Alemanya)) ; Thielen, Alexander (Institute of Immunology and Genetics (Kaiserslautern, Alemanya)) ; Victor, Martin (Roche Applied Science (Penzberg, Alemanya)) ; Metzner, Karin J. (University of Zurich) ; Däumer, Martin P. (Institute of Immunology and Genetics (Kaiserslautern, Alemanya)) ; 454 HIV-1 Alpha Study Group
Ultra deep sequencing is of increasing use not only in research but also in diagnostics. For implementation of ultra deep sequencing assays in clinical laboratories for routine diagnostics, intra- and inter-laboratory testing are of the utmost importance. [...]
2016 - 10.1371/journal.pone.0146687
PloS one, Vol. 11 Núm. 1 (January 2016)  
8.
14 p, 455.3 KB Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia / Llibre Codina, Josep Maria (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Bravo, Isabel (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Ornelas Vargas, Arelly (Universitat de Barcelona. Departament d'Econometria, Estadística i Economia Aplicada) ; Santos Fernández, José Ramón (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Puig, Jordi (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Martín Iguacel, Raquel (Odense University Hospital (Dinamarca)) ; Paredes, Roger (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Universitat Autònoma de Barcelona
BACKGROUND: Switching subjects with persistently undetectable HIV-1 viremia under antiretroviral treatment (ART) to once-daily tenofovir/emtricitabine (or lamivudine) + nevirapine is a cost-effective and well-tolerated strategy. [...]
2015 - 10.1371/journal.pone.0128131
PloS one, Vol. 10 Núm. 6 (June 2015)  

Research literature 4 records found  
1.
164 p, 2.3 MB Next-Generation Virus Genotyping for HIV-1 Surveillance and Clinical Management / Casadellà Fontdevila, Maria ; Paredes i Deiros, Roger, dir. ; Farrés i Vicén, Jaume, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Tot i que la infecció pel virus de la immunodeficiència humana de tipus 1 (VIH-1) roman sense cura, la teràpia antiretroviral és capaç de bloquejar de manera persistent la replicació viral, limitant el dany al sistema immunitari. [...]
Although HIV-1 infection cannot be cured, antiretroviral therapy is able to persistently block virus replication, limiting the damage on the immune system. This can prevent and/or revert immune deterioration in most subjects, prolonging life expectancy and increasing its quality. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016
2 documents
2.
173 p, 2.2 MB Clinical impact of HIV-1 resistance against nonnucleoside analogue reverse transcriptase Inhibitors = Impacte clínic de la resistència del VIH-1 als inhibidors de la transcriptassa inversa no anàlegs de nucleòsids / Llibre Codina, Josep Maria ; Paredes i Deiros, Roger, dir. ; Clotet i Sala, Bonaventura, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Els inhibidors de la transcriptassa inversa no anàlegs de nucleòsids (ITINAN) s'utilitzen sovint en el tractament antiretroviral (TAR) per la seva eficàcia i simplicitat. La resistència està causada per mutacions específiques a posicions de resistència. [...]
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are popular components of antiretroviral therapy due to their efficacy and simplicity. Resistance is caused only by specific mutations at drug-resistance positions. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2015  
3.
256 p, 3.4 MB Clinical value of massive Parallel HIV-1 sequencing in antiretroviral treatment-experienced subjects / Pou Gonzàlez, Christian ; Paredes i Deiros, Roger, dir. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Farrés i Vicén, Jaume, tutor (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Els test de resistència al antiretrovirals són utilitzats en la pràctica clínica per la personalització del tractament antiretroviral (TARV) de les persones infectades pel VIH-1. La seqüenciació poblacional (SP) és la tècnica més emprada pel genotipat del VIH-1 obtenint una bona correlació amb la resposta clínica dels pacients. [...]
Los ensayos de resistencia a los antiretrovirales son utilizados en la práctica clínica para la personalización del tratamiento antirretroviral (TARV) de las personas infectadas por el VIH-1. La secuenciación poblacional (SP) es la técnica más utilizada para el genotipado del VIH-1 obteniendo una buena correlación con la respuesta clínica de los pacientes. [...]
Drug resistance testing is utilized in the clinical routine to personalize ART of HIV-1 infected people. Population sequencing is employed for HIV-1 genotyping obtaining good correlations with clinical outcomes. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  
4.
301 p, 3.1 MB Clinical implications of minority HIV-1 resistant variants / Paredes i Deiros, Roger ; Kuritzkes, Daniel R., dir. (Harvard Medical School) ; Clotet i Sala, Bonaventura, dir. (Universitat Autònoma de Barcelona. Departament de Medicina)
Aquesta tesi doctoral per compendi de publicacions avalua la importància clínica de les variants del VIH-1 minoritàries que alberguen mutacions de resistència. La primera publicació presenta una avaluació sistemàtica de la PCR específica d'al·lel (ASPCR) com a eina per detectar variants víriques minoritàries que amb mutacions de resistència a la transcriptasa inversa (M184V, M184I) i proteasa (regions de D30N), així com a la envolta (V38A). [...]
Bellaterra : Universitat Autònoma de Barcelona, 2009  

See also: similar author names
1 Paredes, R
2 Paredes, R.
12 Paredes, Roger
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