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5 p, 1.9 MB The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides / Petchey, Mark (University of York) ; Cuetos, Anibal (University of York) ; Rowlinson, Benjamin (University of York) ; Dannevald, Stephanie (University of York) ; Frese, Amina (University of York) ; Sutton, Peter W. (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Lovelock, Sarah (University of Manchester) ; Lloyd, Richard C. (GSK Medicines Research Centre) ; Fairlamb, Ian J. S. (University of York) ; Grogan, Gideon (University of York)
Amide bond formation is one of the most important reactions in pharmaceutical synthetic chemistry. The development of sustainable methods for amide bond formation, including those that are catalyzed by enzymes, is therefore of significant interest. [...]
2018 - 10.1002/anie.201804592
Angewandte Chemie (International ed. Internet), Vol. 57 (august 2018) , p. 11584-11588  

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