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2 p, 292.1 KB |
Corrigendum : The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases(Front. Immunol., (2023), 14, (1191782), 10.3389/fimmu.2023.1191782)
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Navarro-Compán, Victoria (Hospital Universitario La Paz) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ;
Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ;
Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ;
Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ;
Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ;
Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ;
Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Juanola, Xavier (Hospital Universitari de Bellvitge) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Arias-Santiago, Salvador (Universidad de Granada) ;
Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ;
Queiro, Ruben (Hospital Universitario Central de Asturias) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
In the published article, there was an error in Table 1 as published. The cell corresponding to ixekizumab in HS must be yellow rather than green, since it is not approved for that indication, nor has phase 3 clinical development been published. [...]
2023 -  10.3389/fimmu.2023.1332177
Frontiers in immunology, Vol. 14 (2023) , p. 1332177
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9 p, 748.2 KB |
Unmet Needs in the Management of Moderate-to-Severe Psoriasis in Spain : A Multidimensional Evaluation
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Zozaya, Néboa (Universidad de Las Palmas de Gran Canaria) ;
Villoro, Renata (Weber Foundation) ;
Abdalla, Fernando (Weber Economía y Salud) ;
Alfonso Zamora, Santiago (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Balea Filgueiras, Jesús (Complejo Hospitalario Universitario de Ferrol) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Delgado Sánchez, Olga (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Dolz Sinisterra, Francisco (Hospital Universitari Doctor Peset (València)) ;
García-Ruiz, Antonio (Instituto de Investigación Biomédica de Málaga) ;
Herranz Pinto, Pedro (Hospital Universitario La Paz (Madrid)) ;
Manfredi, Antonio (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Martínez Olmos, José (Escuela Andaluza de Salud Pública) ;
Morales de los Ríos, Paloma (Hospital General Universitario Gregorio Marañón) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Ros Abarca, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Hidalgo, Álvaro (Universidad de Castilla-La Mancha) ;
Universitat Autònoma de Barcelona
Psoriasis is a chronic, systemic inflammatory disease that affects the skin, with a high impact on patients' quality of life. The aim of this study was to identify and determine the relative importance of unmet needs in the management of moderate-to-severe psoriasis in Spain, from a multi-stakeholder perspective. [...]
2022 - 10.2340/actadv.v102.583
Acta dermato-venereologica, Vol. 102 (2022) , p. adv00678
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Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis using a multidisciplinary reflective multi-criteria decision analysis
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Zozaya, Néboa (Universidad de Las Palmas de Gran Canaria) ;
Abdalla, Fernando (Weber (Madrid)) ;
Alfonso Zamora, Santiago (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Balea Filgueiras, Jesus (Complejo Hospitalario Universitario de Ferrol) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Delgado Sánchez, Olga (Hospital Universitari Son Espases)) ;
Dolz Sinisterra, Francisco (Hospital Universitari Doctor Peset (València)) ;
García-Ruiz, Antonio (Instituto de Investigación Biomédica de Málaga) ;
Herranz Pinto, Pedro (Hospital Universitario La Paz (Madrid)) ;
Manfredi, Antonio (Psoriasis and Psoriatic Arthritis Patient and Family Association) ;
Martínez Olmos, José (Escuela Andaluza de Salud Pública (Granada, Andalusia)) ;
Morales de Los Ríos Luna, Paloma (Hospital General Universitario Gregorio Marañón) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Ros Abarca, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Hidalgo-Vega, Álvaro (Universidad de Castilla-La Mancha) ;
Universitat Autònoma de Barcelona
Background: Multi-criteria decision analysis (MCDA) was proposed to surmount arbitrary clinical decisions in the field of biological therapies for psoriatic patients. At the same time, MCDA may further highlight the potential of bimekizumab for the treatment of moderate-to-severe psoriasis, compared to placebo, adalimumab, ustekinumab, secukinumab, and even ixekizumab and risankizumab. [...]
2022 - 10.1080/14737167.2022.2063842
Expert Review of Pharmacoeconomics and Outcomes Research, Vol. 22 Núm. 6 (2022) , p. 941-953
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14 p, 4.2 MB |
The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases
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Navarro-Compán, Victoria (Hospital Universitario La Paz) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ;
Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ;
Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ;
Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ;
Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ;
Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ;
Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Juanola, Xavier (Hospital Universitari de Bellvitge) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Arias-Santiago, Salvador (Universidad de Granada) ;
Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ;
Queiro, Ruben (Hospital Universitario Central de Asturias) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Interleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F); sequence homology is highest between IL-17A and IL-17F, displaying certain overlapping functions. In general, IL-17A and IL-17F play important roles in chronic inflammation and autoimmunity, controlling bacterial and fungal infections, and signaling mainly through activation of the nuclear factor-kappa B (NF-κB) pathway. [...]
2023 - 10.3389/fimmu.2023.1191782
Frontiers in immunology, Vol. 14 (august 2023)
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9 p, 267.2 KB |
A Topical Treatment Optimization Programme (TTOP) improves clinical outcome for calcipotriol/betamethasone gel in psoriasis : results of a 64-week multinational randomized phase IV study in 1790 patients (PSO-TOP)
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Reich, Kristian (SCIderm GmbH) ;
Zschocke, I. (SCIderm GmbH) ;
Bachelez, Hervé (AP-HP Hôpital Saint-Louis) ;
de Jong, E.M.G.J. (Radboud University Medical Centre and Radboud University) ;
Gisondi, Paolo (University of Verona) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Warren, R. B. (Manchester Academic Health Science Centre) ;
Ortland, C. (Das Forschungsdock Service for Clinical Development) ;
Mrowietz, Ulrich (University Medical Center Schleswig-Holstein) ;
Universitat Autònoma de Barcelona
Around two-thirds of patients with psoriasis do not adhere to topical treatment. The Topical Treatment Optimization Programme (TTOP), a five-element tool, includes guidance for the conversation between dermatologists/nurses and patients, patient information material, telephone/e-mail helpdesks and treatment reminders. [...]
2017 - 10.1111/bjd.15466
British journal of dermatology, Vol. 177 Núm. 1 (july 2017) , p. 197-205
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7 p, 283.2 KB |
A European subset analysis from the population-based Multinational Assessment of Psoriasis and Psoriatic Arthritis shows country-specific features : results from psoriasis patients in Spain
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Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
van de Kerkhof, P. C. M. (Radboud University Nijmegen Medical Centre) ;
Reich, Kristian (Sclderm Research Institute and Dermatologikum Hamburg) ;
Bachelez, Hervé (Sorbonne Paris Cité Université Paris Diderot) ;
Barker, J.N (King's College London) ;
Girolomoni, G. (University of Verona) ;
Paul, C. (Paul Sabatier University and Larrey Hospital) ;
Universitat Autònoma de Barcelona
The Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) survey data were not analysed to account for cultural and healthcare system differences across European countries (EC). To utilize MAPP data to characterize psoriasis in Spanish patients, including severity assessment and Dermatology Life Quality Index (DLQI). [...]
2017 - 10.1111/jdv.14195
Journal of the European Academy of Dermatology and Venereology, Vol. 31 Núm. 7 (july 2017) , p. 1176-1182
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13 p, 782.3 KB |
GCAT|Genomes for life : A prospective cohort study of the genomes of Catalonia
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Obón-Santacana, Mireia (Hospital Universitari de Bellvitge) ;
Vilardell, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Carreras Nolla, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Duran-Albareda, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Velasco, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Galván-Femenía, Iván (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alonso, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Sumoy, Lauro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Duell, Eric J. (Hospital Universitari de Bellvitge) ;
Perucho, Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Moreno Aguado, Víctor (Universitat de Barcelona) ;
de Cid, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
The prevalence of chronic non-communicable diseases (NCDs) is increasing worldwide. NCDs are the leading cause of both morbidity and mortality, and it is estimated that by 2030, they will be responsible for 80% of deaths across the world. [...]
2018 - 10.1136/bmjopen-2017-018324
BMJ open, Vol. 8 Núm. 3 (january 2018) , p. e018324
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5 p, 414.7 KB |
Long-term impact of ixekizumab on psoriasis itch severity : Results from a phase III clinical trial and long-term extension
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Kimball, Alexandra B. (Beth Israel Deaconess Hospital and Harvard Medical School) ;
Luger, Thomas (University of Muenster) ;
Gottlieb, Alice (New York Medical College) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Kaufmann, Roland (Goethe University) ;
Burge, Russel (University of Cincinnati) ;
Lin, Chen-Yen (Eli Lilly and Company) ;
Yosipovitch, Gil (University of Miami Miller School Of Medicine) ;
Universitat Autònoma de Barcelona
Itching is a prevalent plaque psoriasis symptom. Ixekizumab, an IL-17A antagonist, has demonstrated rapid, significant improvements in itch severity over 12 weeks in Phase III psoriasis trials (UNCOVER-1, UNCOVER-2). [...]
2018 - 10.2340/00015555-2801
Acta dermato-venereologica, Vol. 98 Núm. 1 (2018) , p. 98-102
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10 p, 1.7 MB |
Epidemiology of atopic dermatitis in adults : Results from an international survey
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Barbarot, Sebastien (CHU Nantes) ;
Auziere, S. (Kantar Health) ;
Gadkari, A. (Regeneron) ;
Girolomoni, G. (University of Verona) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Simpson, E.L. (Oregon Health & Science University) ;
Margolis, D.J. (University of Pennsylvania Perelman School of Medicine) ;
de Bruin-Weller, Marjolein (University Medical Center Utrecht) ;
Eckert, L. (Sanofi) ;
Universitat Autònoma de Barcelona
There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. [...]
2018 - 10.1111/all.13401
Allergy, Vol. 73 Núm. 6 (june 2018) , p. 1284-1293
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6 p, 377.9 KB |
Clinical and genetic differences between pustular psoriasis subtypes
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Twelves, Sophie (King's College London) ;
Mostafa, Alshimaa (Beni Suef University) ;
Dand, Nick (King's College London) ;
Burri, Elias (University Hospital Zurich (Suïssa)) ;
Farkas, K. (University of Szeged) ;
Wilson, Rosemary (King's College London) ;
Cooper, Hywel L. (Portsmouth Hospitals Trust) ;
Irvine, Alan D. (Trinity College Dublin) ;
Oon, Hazel H. (National Skin Centre) ;
Kingo, Külli (Tartu University Hospital (Tartu, Estònia)) ;
Köks, Sulev (University of Tartu) ;
Mrowietz, Ulrich (University Medical Center Schleswig-Holstein) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Reynolds, Nick (Newcastle Hospitals NHS Foundation Trust) ;
Tan, Euegene Sern-Ting (National Skin Centre) ;
Tanew, Adrian (Medical University of Vienna) ;
Torz, Kaspar (Campus Kiel) ;
Trattner, Hannes (Medical University of Vienna) ;
Valentine, Mark (University of Washington School of Medicine) ;
Wahie, Shyamal (University Hospital of North Durham and Darlington Memorial Hospital) ;
Warren, Richard B. (University of Manchester and the Academic Health Science Centre) ;
Wright, Andrew (St University of Bradford) ;
Bata-Csörgő, Zsuzsa (University of Szeged) ;
Szell, Marta (University of Szeged) ;
Griffiths, Christopher E.M. (University of Manchester and the Academic Health Science Centre) ;
Burden, A.David (University of Glasgow) ;
Choon, Siew-Eng (Monash University Malaysia) ;
Smith, Catherine H. (King's College London) ;
Barker, Jonathan N. (King's College London) ;
Navarini, Alexander A. (University Hospital Zurich (Suïssa)) ;
Capon, Francesca (King's College London) ;
Universitat Autònoma de Barcelona
The term pustular psoriasis indicates a group of severe skin disorders characterized by eruptions of neutrophil-filled pustules. The disease, which often manifests with concurrent psoriasis vulgaris, can have an acute systemic (generalized pustular psoriasis [GPP]) or chronic localized (palmoplantar pustulosis [PPP] and acrodermatitis continua of Hallopeau [ACH]) presentation. [...]
2019 - 10.1016/j.jaci.2018.06.038
The Journal of Allergy and Clinical Immunology, Vol. 143 Núm. 3 (march 2019) , p. 1021-1026
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