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7 p, 409.8 KB An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex / Paredes, Ursula M. (University of Liverpool. Institute of Translational Medicine) ; Bubb, Vivien (University of Liverpool. Institute of Translational Medicine) ; Haddley, Katte (University of Liverpool. Institute of Translational Medicine) ; Macho, Gabriele A. (Institut Català de Paleontologia Miquel Crusafont) ; Quinn, John P. (University of Liverpool. Institute of Translational Medicine)
Background: detecting functional variants contributing to diversity of behaviour is crucial for dissecting genetics of complex behaviours. At a molecular level, characterisation of variation in exons has been studied as they are easily identified in the current genome annotation although the functional consequences are less well understood; however, it has been difficult to prioritise regions of non-coding DNA in which genetic variation could also have significant functional consequences. [...]
2011 - 10.1186/1471-2202-12-46
BMC neuroscience, Vol. 12 (2011) , art. 46  

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