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Resultados globales: 9 registros encontrados en 0.02 segundos.
Artículos, Encontrados 8 registros
Documentos de investigación, Encontrados 1 registros
Artículos Encontrados 8 registros  
1.
13 p, 5.4 MB Gastroprotective Effects of Oral Glycosaminoglycans with Sodium Alginate in an Indomethacin-Induced Gastric Injury Model in Rats / Traserra, Sara (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Cuerda, Héctor (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Vallejo, Adriana (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Segarra, Sergi (R&D Bioiberica S.A.U., Esplugues de Llobregat) ; Sabata, Roger (R&D Bioiberica S.A.U., Esplugues de Llobregat) ; Jiménez Farrerons, Marcel (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
The gastrointestinal (GI) mucosal barrier is often exposed to inflammatory and erosive insults, resulting in gastric lesions. Glycosaminoglycans (GAGs), such as hyaluronic acid (HA), chondroitin sulfate (CS), and N-acetylglucosamine (NAG) have shown potential beneficial effects as GI protectants. [...]
2023 - 10.3390/vetsci10120667
Veterinary Sciences, Vol. 10 (november 2023)  
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2.
12 p, 1.7 MB Sphingomyelin-Rich Lipid Extract Collar for Canine Atopic Dermatitis / Segarra, Sergi (R&D Bioiberica S.A.U.) ; Sanmiguel, David (Clínica Veterinaria Wecan De Carreres) ; Zuriaga, Eliseo (Hospital Veterinario Global) ; Leclerc, Sophie (AB7 Santé, BP) ; Seigneuric, Estelle (AB7 Santé) ; Miquel, Aurélie (AB7 Santé) ; Vázquez Fariñas, Ana (Universitat Autònoma de Barcelona. Servei d'Estadística Aplicada) ; Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Canine atopic dermatitis (CAD) is a chronic skin disease which can be very frustrating for veterinarians and pet guardians. Adherence to treatment is key when managing CAD cases. For this reason, we developed and tested a new product for CAD (Atopivet ® collar, Bioiberica SAU, Esplugues de Llobregat, Spain) which is easy to administer and could help reduce monthly treatment costs. [...]
2023 - 10.3390/vetsci10060389
Veterinary Sciences, Vol. 10 (june 2023)  
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3.
7 p, 2.0 MB Effects of sphingolipid extracts on the morphological structure and lipid profile in an in vitro model of canine skin / Cerrato Tomàs, Santiago (UNIVET) ; Ramió-Lluch, Laura (UNIVET) ; Brazis, Pilar (UNIVET) ; Fondevila, Dolors (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Segarra, Sergi (R&D Veterinary Division) ; Puigdemont Rodriguez, Anna (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Ceramides (CER) are essential sphingolipids of the stratum corneum (SC) that play an important role in maintaining cutaneous barrier function. Skin barrier defects occur in both human beings and dogs affected with atopic dermatitis, and have been associated with decreased CER concentrations and morphological alterations in the SC. [...]
2016 - 10.1016/j.tvjl.2016.03.020
The Veterinary Journal, Vol. 212 (2016) , p. 58-64  
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4.
10 p, 2.7 MB Topical treatment with SPHINGOLIPIDS and GLYCOSAMINOGLYCANS for canine atopic dermatitis / Marsella, Rosanna (University of Florida. Department of Small Animal Clinical Sciences) ; Segarra, Sergi (R&D Bioiberica) ; Ahrens, Kim (University of Florida. Department of Small Animal Clinical Sciences) ; Alonso, Cristina (OWL Metabolomics) ; Ferrer i Caubet, Lluís (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Skin barrier dysfunction plays a key role in atopic dermatitis (AD). This impairment is related to altered composition and metabolism of epidermal sphingolipids and a deficiency of ceramides. Glycosaminoglycans (GAGs), and especially hyaluronic acid, could be useful in the management of AD. [...]
2020 - 10.1186/s12917-020-02306-6
BMC veterinary research, Vol. 16 (march 2020)  
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5.
9 p, 983.1 KB A dose-escalation ex vivo study on the effects of intracameral benzalkonium chloride in rabbits / Segarra, Sergi ; Leiva Repiso, Marta (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Costa Moya, Daniel (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari) ; Coyo Asensio, Natàlia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Sabés-Alsina, Maria ; Ríos, José ; Peña, Teresa (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Rabbits are currently not a good model for studying diseases of the corneal endothelium because their corneal endothelial cells (CECs) maintain a high proliferative capacity throughout almost all their life. [...]
2018 - 10.1186/s12917-018-1349-8
BMC veterinary research, Vol. 14 (february 2018)  
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6.
9 p, 1.0 MB Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease : a randomized, controlled clinical trial / Segarra, Sergi ; Martínez-Subiela, Silvia ; Cerdà-Cuéllar, Marta (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Martínez-Puig, Daniel ; Muñoz-Prieto, Alberto ; Rodríguez Franco, Fernando (Universidad Complutense de Madrid. Departamento de Medicina y Cirugía Animal) ; Rodríguez-Bertos, Antonio (Universidad Complutense de Madrid) ; Allenspach, Karin ; Velasco, Alfonso ; Cerón, José Joaquín (Universidad de Murcia. Departamento de Patología Animal)
Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. [...]
2016 - 10.1186/s12917-016-0676-x
BMC veterinary research, Vol. 12 (march 2016)  
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7.
7 p, 381.1 KB Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment / Pardo-Marín, Luis (Universidad de Murcia. Facultad de Veterinaria) ; Martínez-Subiela, Silvia (Universidad de Murcia. Facultad de Veterinaria) ; Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Tvarijonaviciute, Asta (Universidad de Murcia. Facultad de Veterinaria) ; Garcia-Martinez, Juan Diego (Universidad de Murcia. Facultad de Veterinaria) ; Segarra, Sergi (R&D Bioiberica S.A.) ; Cerón, José Joaquín (Universidad de Murcia. Facultad de Veterinaria)
Background: The objective of this study was to evaluate and compare the evolution of the profile currently recommended by the International Renal Interest Society (IRIS) (sCr, UPC and sSDMA) with a panel of other different kidney biomarkers during treatment for canine leishmaniosis. [...]
2017 - 10.1186/s12917-017-0956-0
BMC veterinary research, Vol. 13, Núm. 31 (January 2017) , p. 1-7  
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8.
13 p, 871.5 KB A Genetic Predictive Model for Canine Hip Dysplasia : Integration of Genome Wide Association Study (GWAS) and Candidate Gene Approaches / Bartolomé, Nerea (Progenika Biopharma) ; Segarra, Sergi (R&D Bioiberica S.A.) ; Artieda, Marta (Progenika Biopharma) ; Francino, Olga (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Sánchez i Robert, Elisenda (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Szczypiorska, Magdalena (Progenika Biopharma) ; Casellas Vidal, Joaquim (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Tejedor, Diego (Progenika Biopharma) ; Cerdeira, Joaquín (Centro Veterinario Aluche Las Águilas (Madrid)) ; Martínez, Antonio (Progenika Biopharma) ; Velasco, Alfonso (R&D Bioiberica S.A.) ; Sánchez Bonastre, Armando (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Canine hip dysplasia is one of the most prevalent developmental orthopedic diseases in dogs worldwide. Unfortunately, the success of eradication programs against this disease based on radiographic diagnosis is low. [...]
2015 - 10.1371/journal.pone.0122558
PloS one, Vol. 10, Num. 4 (April 2015) , p. 1-13  
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Documentos de investigación Encontrados 1 registros  
1.
175 p, 6.1 MB Estudios de escalada de dosis sobre los efectos del cloruro de benzalconio intracameral en conejos : un modelo animal de enfermedad endotelial corneal / Segarra, Sergi ; Leiva Repiso, Marta, dir. ; Peña Giménez, Ma. Teresa, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals
Objetivo: Hallar una dosis de cloruro de benzalconio (BAC) que, inyectada por vía intracameral en conejos, provoque daño selectivo sobre el endotelio corneal, sin afectar al resto de estructuras intraoculares, creando un modelo animal repetible y reproducible de enfermedad endotelial corneal. [...]
Objective: Find a dose of benzalkonium chloride (BAC) which, injected into the anterior chamber in rabbits, causes a selective damage on the corneal endothelium, without affecting the rest of intraocular structures and thus can be used to induce a repeatable and reproducible animal model of corneal endothelial disease. [...]
Bellaterra : Universitat Autònoma de Barcelona, 2016  
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2 Segarra, S.
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