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Artículos Encontrados 2 registros  
1.
16 p, 2.3 MB Identification of genetic elements in metabolism by high-throughput mouse phenotyping / Rozman, Jan (German Center for Diabetes Research) ; Rathkolb, Birgit (Ludwig Maximilians Universität München. Institute of Molecular Animal Breeding and Biotechnology) ; Oestereicher, Manuela A. (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Schütt, Christine (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Ravindranath, Aakash Chavan (Helmholtz Zentrum München. Institute of Bioinformatics and Systems Biology) ; Leuchtenberger, Stefanie (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Sharma, Sapna (Helmholtz Zentrum München. Institute of Epidemiology II) ; Kistler, Martin (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Willershäuser, Monja (Technical University of Munich. Institute for Food and Health) ; Brommage, Robert (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Meehan, Terrence F. (European Bioinformatics Institute) ; Mason, Jeremy (European Bioinformatics Institute) ; Haselimashhadi, Hamed (European Bioinformatics Institute) ; Hough, Tertius (Medical Research Council Harwell) ; Mallon, Ann-Marie (Medical Research Council Harwell) ; Wells, Sara (Medical Research Council Harwell) ; Santos, Luis (Medical Research Council Harwell) ; Lelliott, Christopher J. (Wellcome Trust Sanger Institute (Regne Unit)) ; White, Jacqueline K. (The Jackson Laboratory) ; Sorg, Tania (Université de Strasbourg) ; Champy, Marie-France (Université de Strasbourg) ; Bower, Lynette R. (University of California. Mouse Biology Program) ; Reynolds, Corey L. (Baylor College of Medicine. Department of Molecular and Human Genetics) ; Flenniken, Ann M. (Mount Sinai Hospital) ; Murray, Stephen A. (The Jackson Laboratory) ; Nutter, Lauryl M. J. (The Hospital for Sick Children) ; Svenson, Karen L. (The Jackson Laboratory) ; West, David (Children's Hospital Oakland Research Institute) ; Tocchini-Valentini, Glauco P. (Monterotondo Mouse Clinic. Institute of Cell Biology and Neurobiology) ; Beaudet, Arthur L. (The Hospital for Sick Children) ; Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Braun, Robert B. (The Jackson Laboratory) ; Dobbie, Michael S. (Australian National University) ; Gao, Xiang (Nanjing University. Collaborative Innovation Center for Genetics and Development) ; Herault, Yann (Université de Strasbourg) ; Moshiri, Ala (School of Medicine U.C. Davis. Department of Ophthalmology and Vision Science) ; Moore, Bret A. (School of Veterinary Medicine U.C. Davis) ; Lloyd, Kent (University of California) ; McKerlie, Colin (The Hospital for Sick Children) ; Masuya, Hiroshi (RIKEN BioResource Center) ; Tanaka, Nobuhiko (RIKEN BioResource Center) ; Flicek, Paul (European Bioinformatics Institute) ; Parkinson, Helen E. (European Bioinformatics Institute) ; Sedlacek, Radislav (Institute of Molecular Genetics. Czech Centre for Phenogenomics) ; Seong, Je Kyung (Seoul National University. College of Veterinary Medicine) ; Wang, Chi-Kuang Leo (National Laboratory Animal Center) ; Moore, Mark (International Mouse Phenotyping Consortium) ; Brown, Steve D. M (Medical Research Council Harwell) ; Tschöp, Matthias H. (Technische Universität München. Department of Medicine) ; Wurst, Wolfgang (Ludwig Maximilians Universität München. Adolf Butenandt Institut) ; Klingenspor, Martin (Technical University of Munich. Institute for Food & Health) ; Wolf, Eckhard (Ludwig Maximilians Universität München. Institute of Molecular Animal Breeding and Biotechnology) ; Beckers, Johannes (Technische Universität München. School of Life Science Weihenstephan) ; Machicao, Fausto (University of Tübingen. Department of Internal Medicine) ; Peter, Andreas (Eberhard Karls University of Tuebingen. Institute for Diabetes Research and Metabolic Diseases) ; Staiger, Harald (Eberhard Karls University Tübingen. Department of Pharmacy and Biochemistry) ; Häring, Hans-Ulrich (Eberhard Karls University of Tuebingen. Institute for Diabetes Research and Metabolic Diseases) ; Grallert, Harald (Ludwig-Maximilians-Universität München) ; Campillos, Monica (Helmholtz Zentrum München. Institute of Bioinformatics and Systems Biology) ; Maier, Holger (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Fuchs, Helmut (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Gailus-Durner, Valerie (Helmholtz Zentrum München. Institute of Experimental Genetics) ; Werner, Thomas (University of Michigan. Internal Medicine Nephrology and Center for Computational Medicine and Bioinformatics) ; De Angelis, Martin Hrabe (Technische Universität München. School of Life Science Weihenstephan)
Metabolic diseases are a worldwide problem but the underlying genetic factors and their relevance to metabolic disease remain incompletely understood. Genome-wide research is needed to characterize so-far unannotated mammalian metabolic genes. [...]
2018 - 10.1038/s41467-017-01995-2
Nature communications, Vol. 9 (January 2018) , art. 288  
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2.
15 p, 1.0 MB R2d2 drives selfish sweeps in the house mouse / Didion, John P. (Carolina Center for Genome Science) ; Morgan, Andrew P. (Carolina Center for Genome Science) ; Yadgary, Liran (Carolina Center for Genome Science) ; Bell, Timothy A. (Carolina Center for Genome Science) ; McMullan, Rachel C. (Carolina Center for Genome Science) ; Ortiz de Solorzano, Lydia (Carolina Center for Genome Science) ; Britton-Davidian, Janice (Université de Montpellier. Institut des Sciences de l'Evolution) ; Bult, Carol J. (The Jackson Laboratory) ; Campbell, Karl J. (The University of Queensland. School of Geography, Planning & Environmental Management) ; Castiglia, Riccardo (Università degli studi di Roma "La Sapienza") ; Ching, Yung-Hao (Tzu Chi University. Department of Molecular Biology and Human Genetics) ; Chunco, Amanda J. (Elon University. Department of Environmental Studies) ; Crowley, James J. (The University of North Carolina at Chapel Hill. Department of Genetics) ; Chesler, Elissa J. (The Jackson Laboratory) ; Förster, Daniel W. (Leibniz-Institut für Zoo- und Wildtierforschung. Department of Evolutionary Genetics) ; French, John E. (National Institute of Environmental Health Sciences. National Toxicology Program) ; Gabriel, Sofia I. (Universidade de Lisboa. Department of Animal Biology) ; Gatti, Daniel M. (The Jackson Laboratory) ; Garland, Theodore (University of California, Riverside. Department of Biology) ; Giagia-Athanasopoulou, Eva B. (University of Patras. Department of Biology) ; Giménez, Mabel D. (Universidad Nacional de Misiones (Argentina). Instituto de Biología Subtropical) ; Grize, Sofia A. (Universität Zürich. Institute of Evolutionary Biology and Environmental Studies) ; Gündüz, İslam (University of Ondokuz Mayis. Department of Biology, Faculty of Arts and Sciences) ; Holmes, Andrew (National Institutes of Health. National Institute on Alcohol Abuse and Alcoholism) ; Hauffe, Heidi C. (Fondazione Edmund Mach. Department of Biodiversity and Molecular Ecology, Research and Innovation Centre) ; Herman, Jeremy S. (National Museums Scotland. Department of Natural Sciences) ; Holt, James M. (The University of North Carolina at Chapel Hill. Department of Computer Science) ; Hua, Kunjie (The University of North Carolina at Chapel Hill. Department of Genetics) ; Jolley, Wesley J. (Island Conservation (Santa Cruz, Califòrnia)) ; Lindholm, Anna K. (Universität Zürich. Institute of Evolutionary Biology and Environmental Studies) ; López-Fuster, María J. (Universitat de Barcelona. Facultat de Biologia) ; Mitsainas, George (University of Patras. Department of Biology) ; da Luz Mathias, Maria (Universidade de Lisboa. Department of Animal Biology) ; McMillan, Leonard (The University of North Carolina at Chapel Hill. Department of Computer Science) ; Ramalhinho, Maria da Graça Morgado (Universidade de Lisboa. Department of Animal Biology) ; Rehermann, Barbara (National Institute of Diabetes and Digestive and Kidney Diseases (Bethesda, Estats Units d'Amèrica)) ; Rosshart, Stephan P. (National Institute of Diabetes and Digestive and Kidney Diseases (Bethesda, Estats Units d'Amèrica)) ; Searle, Jeremy B. (Cornell University. Department of Ecology and Evolutionary Biology) ; Shiao, Meng-Shin (Mahidol University. Faculty of Medicine) ; Solano, Emanuela (Università degli studi di Roma "La Sapienza") ; Svenson, Karen L. (The Jackson Laboratory) ; Thomas-Laemont, Patricia (Elon University. Department of Environmental Studies) ; Threadgill, David W. (Texas A&M University. Department of Molecular and Cellular Medicine) ; Ventura Queija, Jacinto (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Weinstock, George M. (Jackson Laboratory for Genomic Medicine) ; Pomp, Daniel (Carolina Center for Genome Science) ; Churchill, Gary A. (The Jackson Laboratory) ; Pardo-Manuel de Villena, Fernando (Carolina Center for Genome Science)
A selective sweep is the result of strong positive selection driving newly occurring or standing genetic variants to fixation, and can dramatically alter the pattern and distribution of allelic diversity in a population. [...]
2016 - 10.1093/molbev/msw036
Molecular biology and evolution, Vol. 33, issue 6 (June 2016) , p. 1381-1395  
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