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2 p, 292.1 KB |
Corrigendum : The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases(Front. Immunol., (2023), 14, (1191782), 10.3389/fimmu.2023.1191782)
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Navarro-Compán, Victoria (Hospital Universitario La Paz) ;
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ;
Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ;
Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ;
Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ;
Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ;
Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ;
Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Juanola, Xavier (Hospital Universitari de Bellvitge) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Arias-Santiago, Salvador (Universidad de Granada) ;
Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ;
Queiro, Ruben (Hospital Universitario Central de Asturias) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
In the published article, there was an error in Table 1 as published. The cell corresponding to ixekizumab in HS must be yellow rather than green, since it is not approved for that indication, nor has phase 3 clinical development been published. [...]
2023 -  10.3389/fimmu.2023.1332177
Frontiers in immunology, Vol. 14 (2023) , p. 1332177
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14 p, 4.2 MB |
The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases
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Navarro-Compán, Victoria (Hospital Universitario La Paz) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ;
Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ;
Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ;
Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ;
Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ;
Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ;
Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ;
Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Juanola, Xavier (Hospital Universitari de Bellvitge) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Arias-Santiago, Salvador (Universidad de Granada) ;
Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ;
Queiro, Ruben (Hospital Universitario Central de Asturias) ;
Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Interleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F); sequence homology is highest between IL-17A and IL-17F, displaying certain overlapping functions. In general, IL-17A and IL-17F play important roles in chronic inflammation and autoimmunity, controlling bacterial and fungal infections, and signaling mainly through activation of the nuclear factor-kappa B (NF-κB) pathway. [...]
2023 - 10.3389/fimmu.2023.1191782
Frontiers in immunology, Vol. 14 (august 2023)
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15 p, 3.7 MB |
Large T cell clones expressing immune checkpoints increase during multiple myeloma evolution and predict treatment resistance
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Botta, Cirino (Clínica Universidad de Navarra) ;
Perez, Cristina (Clínica Universidad de Navarra) ;
Larrayoz, Marta (Clínica Universidad de Navarra) ;
Puig, Noemí (Hospital Universitario de Salamanca) ;
Cedena, María Teresa (Hospital Universitario 12 de Octubre) ;
Termini, Rosalinda (Clínica Universidad de Navarra) ;
Goicoechea, Ibai (Clínica Universidad de Navarra) ;
Rodriguez, Sara (Clínica Universidad de Navarra) ;
Zabaleta, Aintzane (Clínica Universidad de Navarra) ;
Lopez, Aitziber (Clínica Universidad de Navarra) ;
Sarvide, Sarai (Clínica Universidad de Navarra) ;
Blanco, Laura (Clínica Universidad de Navarra) ;
Papetti, Daniele Marco (Department of Informatics. University of Milano-Bicocca) ;
Nobile, M.S. (Biostatistics and Bioimaging Centre-B4) ;
Besozzi, Daniela (Biostatistics and Bioimaging Centre-B4) ;
Gentile, Massimo (Department of Oncohematology. "Annunziata" Hospital) ;
Correale, Pierpaolo (Great Metropolitan Hospital "Riuniti" of Reggio Calabria) ;
Siragusa, Sergio (Department of Health Promotion. University of Palermo) ;
Oriol, Albert (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
González-Garcia, Maria Esther (Hospital Universitario de Cabueñes (Gijón)) ;
Sureda, Anna (Institut d'Investigació Biomèdica de Bellvitge) ;
de Arriba, Felipe (Instituto Murciano de Investigación Biosanitaria) ;
Ríos-Tamayo, Rafael (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Moraleda, José María (Instituto Murciano de Investigación Biosanitaria) ;
Gironella, Mercedes (Hospital Universitari Vall d'Hebron) ;
Hernández, Miguel T. (Hospital Universitario de Canarias (Illes Canàries)) ;
Bargay, Joan (Hospital Universitari Son Llàtzer (Illes Balears)) ;
Palomera, Luís (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Pérez-Montaña, Albert (Hospital Universitari Son Espases (Illes Balears)) ;
Goldschmidt, Hartmut (Department of Internal Medicine V. University of Heidelberg) ;
Avet-Loiseau, Hervé (IUC-T Oncopole) ;
Roccaro, Aldo (Department of Hematology. ASST Spedali Civili di Brescia) ;
Orfao, Alberto (Universidad de Salamanca. Departament de Medicina) ;
Martinez-Lopez, Joaquín (Hospital Universitario 12 de Octubre) ;
Rosiñol, Laura (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lahuerta, J. J (Hospital Universitario 12 de Octubre) ;
Bladé Creixenti, Juan (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mateos, M. V (Hospital Universitario de SalamancaBiomedica de Salamanca (IBSAL). Centro de Investigación del Cancer (IBMCC-USAL. CSIC)) ;
San-Miguel, J (Clínica Universidad de Navarra) ;
Martinez Climent, Juan-José (Clínica Universidad de Navarra) ;
Paiva, Bruno (Clínica Universidad de Navarra)
Tumor recognition by T cells is essential for antitumor immunity. A comprehensive characterization of T cell diversity may be key to understanding the success of immunomodulatory drugs and failure of PD-1 blockade in tumors such as multiple myeloma (MM). [...]
2023 - 10.1038/s41467-023-41562-6
Nature communications, Vol. 14 Núm. 1 (december 2023) , p. 5825
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12 p, 5.4 MB |
Impaired antigen-specific B-cell responses after Influenza vaccination in kidney transplant recipients receiving co-stimulation blockade with Belatacept
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Pernin, Vincent (University Hospital of Montpellier (França)) ;
Meneghini, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torija Recasens, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jouve, Thomas (Grenoble University Hospital) ;
Del Bello, Arnaud (Universidad de Valladolid) ;
Sanz-Muñoz, Iván (Universidad de Valladolid) ;
Eiros, Jose Maria (Universidad de Valladolid) ;
Donadeu, Laura (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Puig-Polo, Carol (Hospital Universitari de Bellvitge) ;
Morandeira Rego, Francisco (Hospital Universitari de Bellvitge) ;
Navarro Velázquez, Sergio (Hospital Universitari de Bellvitge) ;
Masuet-Aumatell, Cristina (Hospital Universitari de Bellvitge) ;
Favà, Alexandre (Hospital Universitari de Bellvitge) ;
LeQuintrec, Moglie (University Hospital of Montpellier (França)) ;
Kamar, Nassim (Grenoble University Hospital) ;
Crespo, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bestard, Oriol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Emerging data suggest that costimulation blockade with belatacept effectively controls humoral alloimmune responses. However, whether this effect may be deleterious for protective anti-infectious immunity remains poorly understood. [...]
2022 - 10.3389/fimmu.2022.918887
Frontiers in immunology, Vol. 13 (july 2022)
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9 p, 1.0 MB |
Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease
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Zurera Egea, Coral (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zuluaga Blanco, Yenny Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
T cells, natural killer (NK) and NKT cells have opposing actions in the development of alcohol-associated liver fibrosis. We aimed to evaluate the phenotype of NK cells, NKT cells and activated T cells in patients with alcohol use disorder (AUD) according to the presence of advanced liver fibrosis (ALF). [...]
2023 - 10.1007/s10238-023-01121-1
Clinical and Experimental Medicine, Vol. 23, Num. 7 (november 2023) , p. 3539-3547
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12 p, 1.4 MB |
Study of CD27, CD38, HLA-DR and Ki-67 immune profiles for the characterization of active tuberculosis, latent infection and end of treatment
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Díaz-Fernández, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villar-Hernández, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Stojanovic, Zoran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fernández, Marco A (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
De Souza Galvão, Maria Luiza (Hospital Universitari Vall d'Hebron) ;
Tolosa, Guillermo (Universidad de la Frontera) ;
Sánchez-Montalva, Adrián (Hospital Universitari Vall d'Hebron) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Jiménez-Fuentes, María Ángeles (Hospital Universitari Vall d'Hebron) ;
Safont Gonzalez, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Romero i Andrada, Iris (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Sabrià, Josefina (Hospital de Sant Joan Despí Moisès Broggi) ;
Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Latorre, Irene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Current blood-based diagnostic tools for TB are insufficient to properly characterize the distinct stages of TB, from the latent infection (LTBI) to its active form (aTB); nor can they assess treatment efficacy. [...]
2022 - 10.3389/fmicb.2022.885312
Frontiers in microbiology, Vol. 13 (july 2022)
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15 p, 3.5 MB |
Treatment of cardiac fibrosis : from neuro-hormonal inhibitors to CAR-T cell therapy
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Morfino, Paolo (Scuola Superiore Sant'Anna) ;
Aimo, Alberto (Fondazione Toscana Gabriele Monasterio) ;
Castiglione, Vincenzo (Scuola Superiore Sant'Anna) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Emdin, Michele (Fondazione Toscana Gabriele Monasterio) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Cardiac fibrosis is characterized by the deposition of extracellular matrix proteins in the spaces between cardiomyocytes following both acute and chronic tissue damage events, resulting in the remodeling and stiffening of heart tissue. [...]
2022 - 10.1007/s10741-022-10279-x
Heart Failure Reviews, october 2022, p. 1-15
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12 p, 2.9 MB |
Allergen sensitization stratifies IL-31 production by memory T cells in atopic dermatitis patients
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Sans-de San Nicolàs, Lídia (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ;
Figueras-Nart, Ignasi (Hospital Universitari de Bellvitge) ;
García-Jiménez, Irene (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ;
Bonfill-Ortí, Montserrat (Hospital Universitari de Bellvitge) ;
Guilabert, Antonio (Hospital General de Granollers) ;
Curto-Barredo, Laia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Bertolín-Colilla, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ferran, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Serra-Baldrich, E (Institut d'Investigació Biomèdica Sant Pau) ;
Pujol Vallverdú, Ramón M (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Santamaria-Babí, Luis F. (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ;
Universitat Autònoma de Barcelona
The role of allergen sensitization in IL-31 production by T cells and specifically in the clinical context of atopic dermatitis (AD) has not been characterized. The response to house dust mite (HDM) in purified memory T cells cocultured with epidermal cells from AD patients (n=58) and control subjects (n=11) was evaluated. [...]
2023 - 10.3389/fimmu.2023.1124018
Frontiers in immunology, Vol. 14 (march 2023)
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15 p, 5.1 MB |
Slow progression of pediatric HIV associates with early CD8 + T cell PD-1 expression and a stem-like phenotype
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Vieira, Vinicius (Department of Paediatrics, University of Oxford) ;
Lim, Nicholas (Department of Paediatrics, University of Oxford) ;
Singh, Alveera (Africa Health Research Institute) ;
Leitman, Ellen (Department of Paediatrics, University of Oxford) ;
Dsouza, Reena (Department of Paediatrics, University of Oxford) ;
Adland, Emily (Department of Paediatrics, University of Oxford) ;
Muenchhoff, Maximilian (German Center for Infection Research) ;
Roider, Julia (Department of Infectious Diseases, Ludwig-Maximilians-University) ;
Marin Lopez, Miguel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carabelli, Julieta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Giandhari, Jennifer (KwaZulu-Natal Research Innovation and Sequencing Platform, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal) ;
Groll, Andreas (Department of Statistics, TU Dortmund University) ;
Jooste, Pieter (Department of Paediatrics, Kimberley Hospital) ;
Prado, Julia G. (Institut Germans Trias i Pujol) ;
Thobakgale, Christina (University of KwaZulu-Natal) ;
Dong, Krista (Ragon Institute of MGH, MIT and Harvard (Estats Units d'Amèrica)) ;
Kiepiela, Photini (Wits Health Consortium, Johannesburg) ;
Prendergast, Andrew J. (Zvitambo Institute for Maternal and Child Health Research) ;
Tudor-Williams, Gareth (Imperial College London. Centre for Paediatrics and Child Health) ;
Frater, John (Oxford NIHR Biomedical Research Centre) ;
Walker, Bruce D. (Ragon Institute of MGH, MIT and Harvard) ;
Ndung'u, Thumbi (University College London. Division of Infection and Immunity) ;
Ramsuran, Veron (Centre for the AIDS Programme of Research in South Africa) ;
Leslie, Alasdair (School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal) ;
Kløverpris, Henrik N. (Department of Immunology and Microbiology, University of Copenhagen) ;
Goulder, Philip (Doris Duke Medical Research Institute, University of KwaZulu-Natal) ;
Universitat Autònoma de Barcelona
HIV nonprogression despite persistent viremia is rare among adults who are naive to antiretroviral therapy (ART) but relatively common among ART-naive children. Previous studies indicate that ART-naive pediatric slow progressors (PSPs) adopt immune evasion strategies similar to those described in natural hosts of SIV. [...]
202 - 10.1172/jci.insight.156049
JCI Insight, Vol. 8 (february 2023)
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