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45 p, 10.5 MB Lack of adverse effects in subchronic and chronic toxicity/carcinogenicity studies on the glyphosate-resistant genetically modified maize NK603 in Wistar Han RCC rats / Steinberg, Pablo (University of Veterinary Medicine Hannover, Institute for Food Toxicology (Germany)) ; van der Voet, Hilko (Wageningen University and Research. Biometris (The Netherlands)) ; Goedhart, Paul W. (Wageningen University and Research. Biometris (The Netherlands)) ; Kleter, Gijs (RIKILT Wageningen University & Research (The Netherlands)) ; Kok, Esther J. (RIKILT Wageningen University & Research (The Netherlands)) ; Pla, Maria (Centre de Recerca en Agrigenòmica) ; Nadal, Anna (Universitat de Girona. Institut de Tecnologia Agroalimentària) ; Zeljenková, Dagmar. (Slovak Medical University (Slovakia)) ; Aláčová, Radka (Slovak Medical University (Slovakia)) ; Babincová, Júlia (Slovak Medical University (Slovakia)) ; Rollerová, Eva (Slovak Medical University (Slovakia)) ; Jaďuďová, Soňa (Slovak Medical University (Slovakia)) ; Kebis, Anton (Slovak Medical University (Slovakia)) ; Szabová, Elena (Slovak Medical University (Slovakia)) ; Tulinská, Jana (Slovak Medical University (Slovakia)) ; Líšková, Aurélia (Slovak Medical University (Slovakia)) ; Takácsová, Melinda (Slovak Medical University (Slovakia)) ; Mikušová, Miroslava Lehotská (Slovak Medical University (Slovakia)) ; Krivošíková, Zora (Slovak Medical University (Slovakia)) ; Spök, Armin (Alpen-Adria Universität Klagenfurt (Austria)) ; Racovita, Monica (Alpen-Adria Universität Klagenfurt (Austria)) ; de Vriend, Huib (LIS Consult (The Netherlands)) ; Alison, Roger (Roger Alison Ltd. (UK)) ; Alison, Clare (Roger Alison Ltd. (UK)) ; Baumgärtner, Wolfgang (University of Veterinary Medicine Hannover. Department of Pathology (Germany)) ; Becker, Kathrin (University of Veterinary Medicine Hannover. Department of Pathology (Germany)) ; Lempp, Charlotte (University of Veterinary Medicine Hannover. Department of Pathology (Germany)) ; Schmicke, Marion (University of Veterinary Medicine Hannover. Clinic for Cattle (Germany)) ; Schrenk, Dieter (University of Kaiserslautern. Food Chemistry and Toxicology (Germany)) ; Pöting, Annette (Federal Institute for Risk Assessment (Germany)) ; Schiemann, Joachim (Julius Kühn-Institut. Institute for Biosafety in Plant Biotechnology. Federal Research Centre for Cultivated Plants (Germany)) ; Wilhelm, Ralf (Julius Kühn-Institut. Institute for Biosafety in Plant Biotechnology. Federal Research Centre for Cultivated Plants (Germany))
In 2012, a controversial study on the long-term toxicity of a Roundup herbicide and the glyphosate-tolerant genetically modified (GM) maize NK603 was published. The EC-funded G-TwYST research consortium tested the potential subchronic and chronic toxicity as well as the carcinogenicity of the glyphosate-resistant genetically modified maize NK603 by performing two 90-day feeding trials, one with GM maize inclusion rates of 11 and 33% and one with inclusion rates of up to 50%, as well as a 2-year feeding trial with inclusion rates of 11 and 33% in male and female Wistar Han RCC rats by taking into account OECD Guidelines for the testing of chemicals and EFSA recommendations on the safety testing of whole-food/feed in laboratory animals. [...]
2019 - 10.1007/s00204-019-02400-1
Archives of Toxicology, Vol. 93 (February 2019) , p. 1095-1139  

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