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15 p, 4.7 MB |
Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer
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Ortiz-Barahona, Vanessa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Soler, Marta (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Prieto, Carlos A. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Janin, Maxime (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Setien, Fernando (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Fernández-Rebollo, Irene (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bech-Serra, Joan J. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
De La Torre, Carolina (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Guil, Sonia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Villanueva, Alberto (Institut d'Investigació Biomèdica de Bellvitge) ;
Zhang, Pei Hong (Fudan University, Shanghai, China) ;
Yang, Li (Fudan University, Shanghai, China) ;
Guarnacci, Marco (Australian National University, Canberra, Australia) ;
Schumann, Ulrike (Australian National University, Canberra, Australia) ;
Preiss, Thomas (Australian National University, Canberra, Australia) ;
Balaseviciute, Ugne (Hospital Clínic i Provincial de Barcelona) ;
Montal, Robert (Universitat de Lleida) ;
Llovet, Josep M. (Hospital Clínic i Provincial de Barcelona) ;
Esteller, Manel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Background: RNA modifications are important regulators of transcript activity and an increasingly emerging body of data suggests that the epitranscriptome and its associated enzymes are altered in human tumors. [...]
2023 -  10.1186/s12943-023-01785-z
Molecular cancer, Vol. 22 Núm. 1 (may 2023)
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16 p, 1.1 MB |
Genetics in chronic kidney disease : conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
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Köttgen, Anna (Institute of Genetic Epidemiology. Faculty of Medicine and Medical Center. University of Freiburg) ;
Cornec-Le Gall, Emilie (Univ Brest. INSERM UMR 1078. GGB. CHU Brest) ;
Halbritter, Jan (Charité - Universitätsmedizin Berlin) ;
Kiryluk, Krzysztof (Division of Nephrology and Center for Precision Medicine and Genomics. Department of Medicine. Columbia University Irving Medical Center) ;
Mallett, Andrew (KidGen Collaborative. Australian Genomics Health Alliance) ;
Parekh, Rulan (Dalla Lana School of Public Health. and Health Policy. Management and Evaluation. University of Toronto) ;
Rasouly, Hila Milo (Division of Nephrology and Center for Precision Medicine and Genomics. Department of Medicine. Columbia University Irving Medical Center) ;
Sampson, Matthew G. (Kidney Disease Initiative. Broad Institute of MIT and Harvard) ;
Tin, Adrienne (Division of Nephrology. University of Mississippi Medical Center) ;
Antignac, Corinne (Department of Genetics. Necker Hospital. APHP) ;
Ars, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ;
Bergmann, Carsten (Department of Nephrology. Faculty of Medicine and Medical Center. University of Freiburg) ;
Bleyer, Anthony J. (Section on Nephrology. Wake Forest School of Medicine) ;
Bockenhauer, Detlef (Department of Renal Medicine. University College London) ;
Devuyst, Olivier (Department of Physiology. Mechanisms of Inherited Kidney Disorders Group. University of Zurich) ;
Florez, Jose C. (Department of Medicine. Harvard Medical School) ;
Fowler, Kevin J. (The Voice of the Patient. Inc.) ;
Franceschini, Nora (Department of Epidemiology. Gillings School of Global Public Health. University of North Carolina) ;
Fukagawa, Masafumi (Division of Nephrology. Endocrinology and Metabolism. Tokai University School of Medicine) ;
Gale, Daniel (Rare Renal Disease Registry. UK Renal Registry) ;
Gbadegesin, Rasheed A. (Department of Pediatrics. Division of Nephrology. Duke University Medical Center) ;
Goldstein, David B. (Department of Genetics and Development. Columbia University) ;
Grams, Morgan E. (Department of Nephrology. Johns Hopkins University School of Medicine) ;
Greka, Anna (Department of Medicine. Brigham and Women's Hospital. Harvard Medical School) ;
Gross, Oliver (University Medical Center Göttingen) ;
Guay-Woodford, Lisa M. (Center for Translational Science. Children's National Health System) ;
Harris, Peter C. (Division of Nephrology and Hypertension. Mayo Clinic) ;
Hoefele, Julia (Technische Universität München. Institut für Humangenetik) ;
Hung, Adriana M. (VA Tennessee Valley Healthcare System. Division of Nephrology and Hypertension. Department of Medicine. Vanderbilt Center for Kidney Disease. Vanderbilt Precision Nephrology Program. Vanderbilt University Medical Center) ;
Knoers, Nine V.A.M. (Department of Genetics. University Medical Center Groningen) ;
Kopp, Jeffrey B. (Kidney Disease Section. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). National Institutes of Health (NIH)) ;
Kretzler, Matthias (Department of Computational Medicine and Bioinformatics. University of Michigan) ;
Lanktree, Matthew B. (Department of Medicine. McMaster University) ;
Lipska-Ziętkiewicz, Beata S. (Rare Diseases Centre and Clinical Genetics Unit. Department of Biology and Medical Genetics. Medical University of Gdansk) ;
Nicholls, Kathleen (Department of Nephrology. Royal Melbourne Hospital. University of Melbourne) ;
Nozu, Kandai (Department of Pediatrics. Kobe University Graduate School of Medicine) ;
Ojo, Akinlolu (University of Kansas School of Medicine) ;
Parsa, Afshin (Department of Medicine. University of Maryland School of Medicine) ;
Pattaro, Cristian (Eurac Research. Institute for Biomedicine (affiliated with the University of Lübeck)) ;
Pei, York (Division of Nephrology. University Health Network) ;
Pollak, Martin R. (Division of Nephrology. Beth Israel Deaconess Medical Center. Harvard Medical School) ;
Rhee, Eugene P. (Massachusetts General Hospital) ;
Sanna-Cherchi, Simone (Columbia University) ;
Savige, Judy (The University of Melbourne) ;
Sayer, John (NIHR Newcastle Biomedical Research Centre) ;
Scolari, Francesco (Department of Medical and Surgical Specialties. University of Brescia) ;
Sedor, John R. (Case Western Reserve University. Department of Physiology and Biophysics) ;
Sim, Xueling (Saw Swee Hock School of Public Health. National University of Singapore and National University Health System) ;
Somlo, Stefan (Yale University. Department of Genetics) ;
Susztak, Katalin (University of Pennsylvania. Perelman School of Medicine) ;
Tayo, Bamidele O. (Loyola University Chicago. Department of Public Health Sciences) ;
Torra Balcells, Roser (Institut d'Investigació Biomèdica Sant Pau) ;
van Eerde, Albertien M. (Utrecht University Medical Center. Department of Genetics) ;
Weinstock, André (Alport Syndrome Foundation) ;
Winkler, Cheryl A. (Frederick National Laboratory for Cancer Research. National Cancer Institute) ;
Wuttke, Matthias (University of Freiburg) ;
Zhang, Hong (Key Ministry of Health of China. Laboratory of Renal Disease) ;
King, Jennifer M. (August Editorial) ;
Cheung, Michael (KDIGO) ;
Jadoul, Michel (Université Catholique de Louvain. Cliniques Universitaires Saint Luc) ;
Winkelmayer, Wolfgang C. (Baylor College of Medicine. Selzman Institute for Kidney Health) ;
Gharavi, Ali G. (Columbia University Irving Medical Center) ;
Universitat Autònoma de Barcelona
Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as well as genes for complex kidney diseases that manifest in combination with environmental factors, have been discovered. [...]
2022 - 10.1016/j.kint.2022.03.019
Kidney International, Vol. 101 Núm. 6 (june 2022) , p. 1126-1141
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2 p, 444.7 KB |
Molecular Image-Guided Theranostic and Personalized Medicine 2013
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Zhang, Hong (The Second Affiliated Hospital of Zhejiang University, Hangzhou) ;
Tian, Mei (Hangzhou Binjiang Hospital of Zhejiang University, Hangzhou) ;
Carrió, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Civelek, A. Cahid (University of Louisville Medical Center, Louisville) ;
Fujibayashi, Yasuhisa (National Institute of Radiological Sciences, Chiba) ;
Universitat Autònoma de Barcelona
2014 - 10.1155/2014/682527
BioMed Research International, Vol. 2014 (may 2014)
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2 p, 445.4 KB |
Molecular Image-Guided Theranostic and Personalized Medicine 2014
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Zhang, Hong (The Second Affiliated Hospital of Zhejiang University, Hangzhou) ;
Tian, Mei (Hangzhou Binjiang Hospital of Zhejiang University, Hangzhou) ;
Carrió, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Civelek, A. Cahid (NIH Clinical Center, Bethesda) ;
Fujibayashi, Yasuhisa (National Institute of Radiological Sciences, Chiba) ;
Universitat Autònoma de Barcelona
2015 - 10.1155/2015/258612
BioMed Research International, Vol. 2015 (march 2015)
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10 p, 1021.0 KB |
International consensus on the use of tau PET imaging agent 18 F-flortaucipir in Alzheimer's disease
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Tian, Mei (Fudan University) ;
Civelek, A. Cahid (Johns Hopkins Medicine) ;
Carrió, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Watanabe, Yasuyoshi (RIKEN Center for Biosystems Dynamics Research) ;
Kang, Keon Wook (Seoul National University College of Medicine) ;
Murakami, Koji (Juntendo University Hospital) ;
Garibotto, Valentina (Geneva University Hospitals (Suïssa)) ;
Prior, John O. (Lausanne University Hospital) ;
Barthel, Henryk (Leipzig University Medical Center) ;
Zhou, Rui (The Second Affiliated Hospital of Zhejiang University School of Medicine) ;
Hou, Haifeng (The Second Affiliated Hospital of Zhejiang University School of Medicine) ;
Dou, Xiaofeng (The Second Affiliated Hospital of Zhejiang University School of Medicine) ;
Jin, Chentao (The Second Affiliated Hospital of Zhejiang University School of Medicine) ;
Zuo, Chuantao (Fudan University) ;
Zhang, Hong (Zhejiang University) ;
Universitat Autònoma de Barcelona
Positron emission tomography (PET) with the first and only tau targeting radiotracer of 18 F-flortaucipir approved by FDA has been increasingly used in depicting tau pathology deposition and distribution in patients with cognitive impairment. [...]
2022 - 10.1007/s00259-021-05673-w
European Journal of Nuclear Medicine and Molecular Imaging, Vol. 49 (january 2022) , p. 895-904
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18 p, 3.8 MB |
Paternal origins and migratory episodes of domestic sheep
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Deng, Juan (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Xie, Xing-Long (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Wang, Dong-Feng (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Zhao, Chao (Hebei University. College of Life Science (China)) ;
Lv, Feng-Hua (China Agricultural University. College of Animal Science and Technology (China)) ;
Li, Xin (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Yang, Ji (China Agricultural University. College of Animal Science and Technology (China)) ;
Yu, Jia-Lin (Station for Breeding and Improvement of Animal and Poultry of Changshou District (China)) ;
Shen, Min (Xinjiang Academy of Agricultural and Reclamation Sciences. State Key Laboratory of Sheep Genetic Improvement and Healthy Breeding (China)) ;
Gao, Lei (Xinjiang Academy of Agricultural and Reclamation Sciences. State Key Laboratory of Sheep Genetic Improvement and Healthy Breeding (China)) ;
Yang, Jing-Quan (Xinjiang Academy of Agricultural and Reclamation Sciences. State Key Laboratory of Sheep Genetic Improvement and Healthy Breeding (China)) ;
Liu, Ming-Jun (Xinjiang Academy of Animal Science. Animal Biotechnological Research Center (China)) ;
Li, Wen-Rong (Xinjiang Academy of Animal Science. Animal Biotechnological Research Center (China)) ;
Wang, Yu-Tao (Kashi University. College of Life and Geographic Sciences (China)) ;
Wang, Feng (Nanjing Agricultural University. Institute of Sheep and Goat Science (China)) ;
Li, Jin-Quan (Inner Mongolia Agricultural University. College of Animal Science (China)) ;
Hehua, Eer (Ningxia Academy of Agriculture and Forestry Sciences. Grass-Feeding Livestock Engineering Technology Research Center (China)) ;
Liu, Yong-Gang (Yunnan Agricultural University. College of Animal Science and Technology (China)) ;
Shen, Zhi-Qiang (Shandong Binzhou Academy of Animal Science and Veterinary Medicine (China)) ;
Ren, Yan-Ling (Shandong Binzhou Academy of Animal Science and Veterinary Medicine (China)) ;
Liu, Guang-Jian (Novogene Bioinformatics Institute (China)) ;
Chen, Ze-Hui (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Gorkhali, Neena A. (Nepal Agriculture Research Council. National Animal Science Institute. Animal Breeding Division (Nepal)) ;
Rushdi, Hossam E. (Cairo University. Department of Animal Production (Egypt)) ;
Salehian-Dehkordi, H. (Chinese Academy of Sciences. Key Laboratory of Animal Ecology and Conservation Biology) ;
Esmailizadeh, Ali (Shahid Bahonar University of Kerman. Department of Animal Science (Iran)) ;
Nosrati, Maryam (Payame Noor University. Department of Agriculture (Iran)) ;
Paiva, Samuel R. (Embrapa Recursos Genéticos e Biotecnologia (Brazil)) ;
Caetano, Alexandre R. (Embrapa Recursos Genéticos e Biotecnologia (Brazil)) ;
Štěpánek, Ondřej (State Veterinary Institute Jihlava. Department of Virology (Czech Republic)) ;
Olsaker, Ingrid (Norwegian University of Life Sciences. Department of Preclinical Sciences and Pathology (Norway)) ;
Weimann, Christina (Justus-Liebig-University Giessen. Department of Animal Breeding and Genetics (Germany)) ;
Erhardt, Georg (Justus-Liebig-University Giessen. Department of Animal Breeding and Genetics (Germany)) ;
Curik, Ino (University of Zagreb. Department of Animal Science (Croatia)) ;
Kantanen, Juha (Natural Resources Institute Finland. Production Systems (Finland)) ;
Mwacharo, Joram M. (International Center for Agricultural Research in the Dry Areas (Ethiopia)) ;
Hanotte, Olivier (International Livestock Research Institute. LiveGene (Ethiopia)) ;
Bruford, Michael W. (Cardiff University. Sustainable Places Research Institute (UK)) ;
Ciani, Elena (Università degli Studi di Bari Aldo Moro. Dipartimento di Bioscienze, Biotecnologie e Biofarmaceutica (Italy)) ;
Periasamy, Kathiravan (International Atomic Energy Agency. Animal Production and Health Laboratory (Austria)) ;
Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica) ;
Lenstra, Johannes A. (Utrecht University.Faculty of Veterinary Medicine (the Netherlands)) ;
Han, Jian-Lin (International Livestock Research Institute (Nairobi, Kènia)) ;
Zhang, Hong-Ping (Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (China)) ;
Li, Li (Sichuan Agricultural University. Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province (China)) ;
Li, Meng-Hua (China Agricultural University. College of Animal Science and Technology (China))
The domestication and subsequent global dispersal of livestock are crucial events in human history, but the migratory episodes during the history of livestock remain poorly documented [1-3]. Here, we first developed a set of 493 novel ovine SNPs of the male-specific region of Y chromosome (MSY) by genome mapping. [...]
2020 - 10.1016/j.cub.2020.07.077
Current Biology, Vol. 30, Issue 20 (October 2020) , p. 4085-4095
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9 p, 320.6 KB |
Cómo enseñar posedición de traducción automática a una segunda lengua : una propuesta didáctica para el aprendizaje de lenguas
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Zhang, Hong (Universitat Autònoma de Barcelona. Grup Tradumàtica) ;
Torres-Hostench, Olga (Universitat Autònoma de Barcelona. Grup Tradumàtica)
El artículo presenta una propuesta didáctica para poseditar errores de traducción automática (TA) que se ha evaluado mediante pretest/postest con grupo de control y grupo experimental. A partir de los resultados obtenidos se observa que la posedición a una segunda lengua es factible, si bien es recomendable una formación en posedición orientada a tipos de errores específicos y mucha práctica.
L'article presenta una proposta didàctica per a la postedició d'errors de traducció automàtica (TA), avaluada mitjançant pretest/postest amb grup de control i grup experimental. A partir dels resultats obtinguts s'observa que la postedició cap a una segona llengua és factible, tot i que s'aconsella una formació en postedició orientada a tipus d'errors específics i, també, molta pràctica.
This paper presents a training proposal to postedit machine translation (MT) mistakes. The proposal has been assessed by pretest/postest with a control group and an experimental group. Results show that MT postediting to a second language is feasible, although extensive training focused on specific mistakes is recommended.
2019 - 10.5565/rev/tradumatica.237
Tradumàtica, Núm. 17 (2019) , p. 153-161 (Tradumàtica breu)
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50 p, 4.9 MB |
Clp protease and OR directly control the proteostasis of phytoene synthase, the crucial enzyme for carotenoid biosynthesis in Arabidopsis
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Welsch, Ralf (University of Freiburg. Faculty of Biology II) ;
Zhou, Xiangjun (Cornell University. Center for Agriculture and Health) ;
Yuan, Hui (Cornell University. Center for Agriculture and Health) ;
Álvarez, Daniel (University of Freiburg. Faculty of Biology II) ;
Sun, Tianhu (Cornell University. Center for Agriculture and Health) ;
Schlossarek, Dennis (University of Freiburg. Faculty of Biology II) ;
Yang, Yong (Cornell University. Center for Agriculture and Health) ;
Shen, Guoxin (Zhejiang Academy of Agricultural Sciences) ;
Zhang, Hong (Texas Tech University. Department of Biological Sciences) ;
Rodríguez Concepción, Manuel (Centre de Recerca en Agrigenòmica) ;
Thannhauser, Theodore W. (Cornell University. Center for Agriculture and Health) ;
Li, Li (Cornell University. Center for Agriculture and Health)
Phytoene synthase (PSY) is the crucial plastidial enzymein the carotenoid biosynthetic pathway. However, its post-translational regulation remains elusive. Likewise, Clp protease constitutes a central part of the plastid protease network, but its substrates for degradation are not well known. [...]
2018 - 10.1016/j.molp.2017.11.003
Molecular plant, Vol. 11, Issue 1 (January 2018) , p. 149-162
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