MDM4 polymorphisms associated with and increased risk of acute lymphoblastic leukaekmia [i.e. leukemia] in Caucasian populations
Fuentes Palacios, Diego
Armengol Rosell, Gemma, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Universitat Autònoma de Barcelona. Facultat de Biociències

Date:	2015
Description:	1 pag.
Abstract:	Acute lymphoblastic leukemia (ALL) is a well-known malignant disorder affecting both children and adults. Althouhg the therapeutic limits have been maximized and optimized greatly, a better understanding of ALL is required for further improvements as prognostic value and cancer risk, to name a few. The genetic background has been revealed as critical to further improve the prognosis and diagnosis of ALL and other multiple malignant disorders. Hence this project proposes to study the individual genetic polymorphisms in Mdm4, a downstream gene in the P53 pathway in order to determine the susceptibility to this affection in the Caucasain population in Barcelona, Spain.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Studies:	Genètica [2500890]
Study plan:	Grau en Genètica [833]
Document:	Treball final de grau ; Text
Subject:	ALL ; Acute lymphoblastic leukemia ; Caucasian population ; Gen MDM4 ; Leucèmia limfoblàstica aguda ; MDM4 gene ; Població caucàsica ; Polimorfisme ; Polymorphism

1 p, 1.7 MB

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Research literature > Bachelor's degree final project > Biosciences Faculty