Imported malaria in Spain (2009-2016) : results from the +REDIVI Collaborative Network
Norman, Francesca F. (Hospital Universitario Ramón y Cajal (Madrid))
López Polín, Ana (Hospital Universitario Ramón y Cajal (Madrid))
Salvador Vélez, Fernando (Hospital Universitari Vall d'Hebron)
Treviño, Begoña (Hospital Universitari Vall d'Hebron)
Calabuig, Eva (Hospital Universitari i Politècnic La Fe (València))
Torrús-Tendero, Diego (Hospital General Universitario de Alicante (Alacant, País Valencià))
Soriano Arandes, Antonio (Hospital Universitari Vall d'Hebron)
Ruíz Giardín, Jose Manuel (Hospital Universitario de Fuenlabrada ( Madrid))
Monge Maillo, Begoña (Hospital Universitario Ramón y Cajal (Madrid))
Pérez Molina, Jose Antonio (Hospital Universitario Ramón y Cajal (Madrid))
Perez Ayala, Ana (Hospital Universitario 12 de Octubre (Madrid))
García, Magdalena (Hospital General Universitario de Valencia)
Rodríguez, Azucena (Hospital Universitario Central de Asturias)
Martínez Serrano, María (Complejo Hospitalario Universitario de Albacete)
Zubero, Miren (Hospital de Basurto (Bilbao, Biscaia))
López Vélez, Rogelio (Hospital Universitario Ramón y Cajal (Madrid))
Universitat Autònoma de Barcelona

Date:	2017
Abstract:	Imported malaria is a frequent diagnosis in travellers and migrants. The objective of this study was to describe the epidemiological and clinical characteristics of patients diagnosed with imported malaria within a Spanish collaborative network registering imported diseases (+REDIVI). In addition, the possible association between malaria and type of case, gender, age or area of exposure was explored. Cases of imported malaria were identified among all cases registered in the +REDIVI database during the period October 2009-October 2016. Demographic, epidemiological and clinical characteristics were analysed. In total, 11,816 cases of imported infectious diseases were registered in +REDIVI's database between October 2009 and October 2016. Immigrants seen for the first time after migration accounted for 60. 2% of cases, 21. 0% of patients were travellers, and 18. 8% were travellers/immigrants visiting friends and relatives (VFRs). There were 850 cases of malaria (850/11,816, 7. 2%). Malaria was significantly more frequent in men than in women (56. 8% vs 43. 2%) and in VFR-immigrants (52. 6%) as compared to travellers (21. 3%), immigrants (20. 7%) and VFR-travellers (5. 4%) (p < 0. 001). Although this data was not available for most patients with malaria, only a minority (29/217, 13. 4%) mentioned correct anti-malarial prophylaxis. Sub-Saharan Africa was found to be the most common region of acquisition of malaria. Most common reason for consultation after travel was a febrile syndrome although an important proportion of immigrants were asymptomatic and presented only for health screening (27. 3%). Around 5% of travellers presented with severe malaria. The most prevalent species of Plasmodium diagnosed was Plasmodium falciparum (81. 5%). Malaria due to Plasmodium ovale/Plasmodium vivax was frequent among travellers (17%) and nearly 5% of all malaria cases in immigrants were caused by Plasmodium malariae. Malaria was among the five most frequent diagnoses registered in +REDIVI's database. Some significant differences were found in the distribution of malaria according to gender, type of case, species. Among all malaria cases, the most frequent diagnosis was P. falciparum infection in VFR-immigrant men.
Grants:	Instituto de Salud Carlos III RD16/0027/0020
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	Malaria journal, Vol. 16 (October 2017) , art. 407, ISSN 1475-2875

DOI: 10.1186/s12936-017-2057-8
PMID: 29017499

6 p, 909.9 KB

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