miRNAs as potential spermatogenesis biomarkers in patients with non-obstructive azoospermia
Roncero-Carol, Joan
Anton, Ester, dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Universitat Autònoma de Barcelona. Facultat de Biociències

Date:	2019
Abstract:	Non-obstructive azoospermia (NOA) is the most severe diagnosis in cases of male infertility. In some cases of NOA a sperm retrieval can be done by microdissection (microTESE) in order to fertilize oocytes through intracytoplasmic sperm injection (ICSI). However, there is a lack of possible biomarkers for non-invasive diagnosis before the microTESE. The microRNAs (miRNAs) are non-coding RNAs with an essential role in post-transcriptional regulation. They play a great role as regulators of various biological processes, including spermatogenesis. Therefore, the number of studies that seek miRNAs as biomarkers (either of infertility or of spermatogenesis in patients with NOA) is increasing markedly.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Studies:	Ciències Biomèdiques [2501230]
Study plan:	Grau en Ciències Biomèdiques [832]
Document:	Treball final de grau ; Text
Subject:	Non-obstructive azoospermia ; Spermatogenesis ; Sperm retrieval ; Mirna

1 p, 18.1 MB

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Research literature > Bachelor's degree final project > Biosciences Faculty