Iridium oxide (IV) nanoparticle-based lateral flow immunoassay
Quesada-González, Daniel (Institut Català de Nanociència i Nanotecnologia)
Sena Torralba, Amadeo (Institut Català de Nanociència i Nanotecnologia)
Wicaksono, Wiyogo Prio (University of Indonesia. Department of Chemistry)
De La Escosura-Muñiz, Alfredo (Institut Català de Nanociència i Nanotecnologia)
Ivandini, Tribidasari A. (University of Indonesia. Department of Chemistry)
Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)

Date:	2019
Abstract:	Lateral flow biosensors are paper-based devices that allow the detection of different types of analytes with quickness, robustness and selectivity, without leaving behind paper sensors benefits as low-cost, recyclability and sustainability. Nanomaterials have been widely reported in lateral flow biosensors, offering new sensing strategies based on optical or electrical detection techniques. Looking for other advantageous nanomaterials, we propose for the first time the use of iridium oxide (IV) nanoparticles in lateral flow assays for the detection of human immunoglobulin as a model protein. These nanoparticles can be easily prepared and conjugated with biomarkers. Their dark blue color gives a high contrast against the white background of the strips being in this way excellent labels.
Grants:	Ministerio de Economía y Competitividad MAT2017-87202-P Ministerio de Economía y Competitividad SEV-2017-0706
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Iridium oxide nanoparticles ; Lateral flow immunoassay ; Paper-based biosensor ; Mobile phone sensing
Published in:	Biosensors & bioelectronics, Vol. 132 (May 2019) , p. 132-135, ISSN 1873-4235

DOI: 10.1016/j.bios.2019.02.049
PMID: 30870639

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
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Articles > Published articles