New applanation tonometer for myopic patients after laser refractive surgery
Iglesias, María (Instituto Universitario Barraquer)
Yebra, Francisco (Universidade de Vigo. Departamento de Física Aplicada)
Kudsieh, Bachar (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
Laiseca, Andrea (Instituto Universitario Barraquer)
Pereira dos Santos, Cristina Maria (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Nadal Reus, Jeroni (Instituto Universitario Barraquer)
Barraquer, Rafael I. (Rafael Ignasi) (Instituto Universitario Barraquer)
Casaroli-Marano, Ricardo Pedro (Hospital Clínic i Provincial de Barcelona)

Fecha:	2020
Resumen:	This study assesses the agreement between intraocular pressure (IOP) measurements taken with the Goldmann applanation tonometer (GAT) and a new experimental applanation tonometer with a convexly shaped apex (CT) after laser myopic refractive surgery. Two different CT radii (CT1 and CT2) were designed with a finite element analyser, and a prospective double masked study on 102 eyes from 102 patients was carried out. A Bland-Altman plot and intra-class correlation coefficient (ICC) were calculated to assess the agreement between GAT measurements and the measurements of both CT1 and CT2 before and after myopic laser assisted in situ keratomileusis (LASIK; n = 73) and photorefractive keratectomy (PRK; n = 29). We evaluated a subset of two subgroups (n = 36 each) for intra and inter-observer (IA/IE) error. From the whole cohort, the best IOP agreement was observed between GATpre and CT1post surgery: 16. 09 ± 2. 92 vs 16. 42 ± 2. 87 (p < 0. 001); ICC = 0. 675 (95% CI: 0. 554-0. 768). In the analysis of LASIK vs PRK, GATpre and CT1post showed the highest agreement, although LASIK measurements were more accurate than PRK, as the ICC = 0. 718 (95% CI: 0. 594-0. 812) and ICC = 0. 578 (95% CI: 0. 182-0. 795) respectively. Excellent agreement was observed for IA/IE, and there was an ICC > 0. 8 (95% CI) in all cases. CT1 proved more accurate in the LASIK subgroup. In conclusion, our new version of GAT could be used with post-surgery LASIK patients as a more accurate measurement device compared to the current reference tonometer.
Nota:	Ajuts: MI received a personal research grant from the Catalonian Ophthalmology Society 2016-2018 Barcelona, Spain. This society played no role in the design or conduct of this research.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Biophysics ; Medical research
Publicado en:	Scientific reports, Vol. 10 (April 2020) , art. 7053, ISSN 2045-2322

DOI: 10.1038/s41598-020-64013-4
PMID: 32341434

12 p, 1.7 MB

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