Epidemiology and Diagnosis of Tuberculous Lymphadenitis in a Tuberculosis Low-Burden Country
Salvador, Fernando (Hospital Universitari Vall d'Hebron)
Los-Arcos, Ibai (Hospital Universitari Vall d'Hebron)
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron)
Tórtola Fernández, María Teresa (Hospital Universitari Vall d'Hebron)
Curran, Adrian (Hospital Universitari Vall d'Hebron)
Villar, A. (Hospital Universitari Vall d'Hebron)
Saborit, Nuria (Hospital Universitari Vall d'Hebron)
Castellvi, Josep (Hospital Universitari Vall d'Hebron)
Molina Romero, Israel (Hospital Universitari Vall d'Hebron)
Universitat Autònoma de Barcelona

Fecha:	2015
Resumen:	The aim of this article is to describe epidemiological and clinical data of patients with tuberculous lymphadenitis (TL) and evaluate the yield of the diagnostic techniques employed. Retrospective observational study was performed at the Vall d'Hebron University Hospital, Barcelona, Spain. All adult patients with confirmed TL (microbiologically) or probable TL (suspected by clinical presentation, cyto/histopathological features, and clinical improvement after specific treatment) diagnosed from January 2001 to December 2013 were included. One hundred twenty-two patients were included: 78 (63. 9%) patients with confirmed diagnosis and 44 (36. 1%) patients with probable TL. Seventy (57. 4%) patients were nonnative residents. From 83 fine-needle aspiration (FNA) specimens, 54. 8% (40/73) showed granulomatous inflammation, 62. 5% (40/64) had positive mycobacterial culture, and 73. 3% (11/15) tested positive with Xpert MTB/RIF (Cepheid, Sunnyvale, CA). From 62 biopsy samples, 96. 8% (60/62) showed granulomatous inflammation, 64. 6% (31/48) had positive mycobacterial culture, and 46. 1% (6/13) tested positive with Xpert MTB/RIF. TL has increasingly been diagnosed in our setting, mostly because of cases diagnosed in nonnative residents. FNA is an easy and safe technique for the diagnosis of suspected TL, and the yield regarding mycobacterial culture seems to be similar to the obtained with biopsy. The Xpert MTB/RIF test from FNA specimens may increase the accuracy of the TL diagnosis and provides quicker results.
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Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Publicado en:	Medicine, Vol. 94 (january 2015) , ISSN 1536-5964

DOI: 10.1097/MD.0000000000000509
PMID: 25634205

6 p, 213.7 KB

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