Titanium-doped PET nanoplastics of environmental origin as a true-to-life model of nanoplastic
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Vela, Lourdes (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Morataya-Reyes, Michelle (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Llorens-Chiralt, Rquel (Plastics Technological Centre)
Rubio, Laura (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)

Date:	2023
Abstract:	The increased presence of secondary micro/nanoplastics (MNPLs) in the environment requires urgent studies on their potentially hazardous effects on exposed organisms, including humans. In this context, it is essential to obtain representative MNPL samples for such purposes. In our study, we have obtained true-to-life NPLs resulting from the degradation, via sanding, of opaque PET bottles. Since these bottles contain titanium (TiONPs), the resulting MNPLs also contain embedded metal. The obtained PET(Ti)NPLs were extensively characterized from a physicochemical point of view, confirming their nanosized range and their hybrid composition. This is the first time these types of NPLs are obtained and characterized. The preliminary hazard studies show their easy internalization in different cell lines, without apparent general toxicity. The demonstration by confocal microscopy that the obtained NPLs contain Ti samples offers this material multiple advantages. Thus, they can be used in in vivo approaches to determine the fate of NPLs after exposure, escaping from the existing difficulties to follow up MNPLs in biological samples.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00731 Agencia Estatal de Investigación PID2020-116789-RB-C43 Agencia Estatal de Investigación IJC2020r2686I European Commission 965196
Note:	Altres ajuts: acords transformatius de la UAB
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	PET(Ti) nanoplastics ; Obtention ; Characterization ; Cell internalization
Published in:	Science of the total environment, Vol. 880 (July 2023) , art. 163151, ISSN 1879-1026

DOI: 10.1016/j.scitotenv.2023.163151
PMID: 37011676

10 p, 2.4 MB

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