Current Situation of Bacterial Infections and Antimicrobial Resistance Profiles in Pet Rabbits in Spain
Fernández, Mercedes (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Garcias Puigserver, Biel (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Duran, Inma (Departamento Veterinaria de Laboratorio Echevarne)
Molina-López, Rafael A. (Centre de Fauna Salvatge de Torreferrussa (Santa Perpètua de la Mogoda, Catalunya))
Darwich Soliva, Laila (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)

Fecha:	2023
Resumen:	Rabbits are the second most common specialty pet among households in Europe and the USA. However, research on antimicrobial resistance (AMR) in pet rabbits is very scarce. Therefore, scientific data on AMR in pet rabbits is urgently needed as a guide for veterinarian clinicians to optimize antibiotic use in rabbits for reducing the selection of antibiotic resistance. In addition, antimicrobial stewardship programs should be conducted to educate rabbit owners not to misuse antibiotics on their pets as it may put their own health at risk. This paper aims to provide an overview of the current state of AMR in rabbits attended to in veterinary clinics distributed in Spain to highlight the importance of addressing AMR under the One Health approach. Research on antimicrobial resistance (AMR) in pet rabbits is very scarce. The aim of this study was to provide an overview of the current state of AMR in rabbits attended to in veterinary clinics distributed in Spain. Records of 3596 microbiological results of clinical cases submitted from 2010 to 2021 were analyzed. Staphylococcus spp. (15. 8%), Pseudomonas spp. (12. 7%), Pasteurella spp. (10%), Bordetella spp. (9. 6%) and Streptococcus spp. (6. 8%) were the most frequently diagnosed agents. Enterobacteriaceae, principally Escherichia coli, Klebsiella pneumoniae and Enterobacter cloacae, accounted for about 18% of the cases and showed the highest proportion of multi-drug resistance (MDR) isolates, with 48%, 57. 5% and 36% of MDR, respectively. Regarding the antimicrobial susceptibility testing for a number of antimicrobial categories/families, the largest proportion of isolates showing resistance to a median of five antimicrobial categories was observed in P. aeruginosa, Stenotrophomonas maltophilia and Burkolderia spp. In contrast, infections caused by Staphylococcus, Streptococcus spp. and Pasteurella multocida were highly sensitive to conventional antimicrobials authorized for veterinary use (categories D and C). The emergence of AMR major nosocomial opportunistic pathogens such as P. aeruginosa, S. maltophilia and K. pneumoniae in pet rabbits can represent a serious public health challenge. Consequently, collaboration between veterinarians and human health professionals is crucial in the fight against antimicrobial resistance, to optimize, rationalize and prudently use antimicrobial therapies in domestic animals and humans.
Ayudas:	Agència de Gestió d'Ajuts Universitaris i de Recerca FI-SDUR 2020
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Pet rabbits ; Antimicrobial resistance ; One Health approach ; Zoonotic risk ; Spain
Publicado en:	Veterinary Sciences, Vol. 10 (may 2023) , ISSN 2306-7381

DOI: 10.3390/vetsci10050352
PMID: 37235435

13 p, 2.8 MB

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