Opportunistic Community Screening of Chronic Chagas Disease Using a Rapid Diagnosis Test in Pharmacies in Barcelona (Catalonia, Spain) : Study Protocol and Pilot Phase Results
Silgado, Aroa (Hospital Universitari Vall d'Hebron)
Bosch-Nicolau, Pau (Hospital Universitari Vall d'Hebron)
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron)
Cervià, Ariadna (Col·legi de Farmacèutics de Barcelona)
Gómez i Prat, Jordi (Hospital Universitari Vall d'Hebron)
Bagaria, Guillermo (Col·legi de Farmacèutics de Barcelona)
Rodríguez, Cristina (Col·legi de Farmacèutics de Barcelona)
Goterris, Lidia (Hospital Universitari Vall d'Hebron)
Serre-Delcor, Núria (Hospital Universitari Vall d'Hebron)
Oliveira-Souto, Inés (Hospital Universitari Vall d'Hebron)
Salvador, Fernando (Hospital Universitari Vall d'Hebron)
Molina Romero, Israel (Hospital Universitari Vall d'Hebron)
Sulleiro Igual, Elena (Hospital Universitari Vall d'Hebron)
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed consent form, recording the patient's data in a web-based database system, and performing the rapid test and blood collection on dry paper. Nineteen pharmacies participated and 64 patients were included during the pilot phase of the study. The rapid diagnostic test (RDT) was positive in 2/64 (3. 13%) cases. Of the 49 DBS samples that arrived at the laboratory, 22 (45%) were collected incorrectly. After quantitative and qualitative assessment of the program, the dry paper sample and passive strategy were ruled out. DBS sampling and the passive strategy are not suitable for CD screening in community pharmacies. There is a need to expand the number of participating pharmacies and individuals to determine whether conducting a RDT in community pharmacies is an effective screening method to increase access to CD diagnosis in a non-endemic area.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Chagas disease ; Community pharmacies ; Dried blood ; Opportunistic screening ; Rapid test
Published in:	International Journal of Public Health, Vol. 67 (november 2022) , ISSN 1661-8564

DOI: 10.3389/ijph.2022.1605386
PMID: 36531607

8 p, 1.2 MB

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