Strategies for the Preparation of Phosphorus Janus Dendrimers and Their Properties
Cejas-Sánchez, Joel (Universitat Autònoma de Barcelona. Departament de Química)
Kajetanowicz, Anna (University of Warsaw. Biological and Chemical Research Centre)
Grela, Karol (University of Warsaw. Biological and Chemical Research Centre)
Caminade, Anne-Marie (Université de Toulouse)
Sebastián Pérez, Rosa Maria (Universitat Autònoma de Barcelona. Departament de Química)

Date:	2023
Abstract:	Dendrimers, being highly branched monodispersed macromolecules, predominantly exhibit identical terminal functionalities within their structural framework. Nonetheless, there are instances where the presence of two distinct surface functionalities becomes advantageous for the fulfilment of specific properties. To achieve this objective, one approach involves implementing Janus dendrimers, consisting of two dendrimeric wedges terminated by dissimilar functionalities. The prevalent method for creating these structures involves the synthesis of dendrons that possess a core functionality that complements that of a second dendron, facilitating their coupling to generate the desired dendrimers. In this comprehensive review, various techniques employed in the fabrication of phosphorus-based Janus dendrimers are elucidated, displaying the different coupling methodologies employed between the two units. The advantages of phosphorus dendrimers over classic dendrimers will be shown, as the presence of at least one phosphorus atom in each generation allows for the easy monitoring of reactions and the confirmation of purity through a simple technique such as 31 P NMR, as these structures typically exhibit easily interpretable patterns.
Grants:	European Commission 860322 Agencia Estatal de Investigación PID2019-106171RB-I00 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00064
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Subject:	Phosphorus chemistry ; Janus dendrimers ; Dendrons ; 31 P NMR spectroscopy
Published in:	Molecules, Vol. 28, Issue 14 (July 2023) , art. 5570, ISSN 1420-3049

DOI: 10.3390/molecules28145570
PMID: 37513445

18 p, 6.8 MB

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