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23 p, 3.1 MB Short-Acting Beta-2-Agonist Exposure and Severe Asthma Exacerbations : SABINA Findings From Europe and North America / Quint, Jennifer K. (Imperial College London) ; Arnetorp, Sofie (Payer Analytics. AstraZeneca) ; Kocks, Janwillem W.H. (University Medical Center Groningen) ; Kupczyk, Maciej (Karolinska Institutet (Estocolm, Suècia)) ; Nuevo, Javier (Evidence Generation. AstraZeneca) ; Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ; Cabrera, Claudia (BioPharmaceuticals Medical (Evidence). AstraZeneca) ; Raherison-Semjen, Chantal (Bordeaux University) ; Walker, Brandie (University of Calgary) ; Penz, Erika (University of Saskatchewan) ; Gilbert, Ileen (Medical Affairs. AstraZeneca) ; Lugogo, Njira Lucia (University of Michigan) ; van der Valk, Ralf J.P. (Medical Affairs. AstraZeneca) ; Fong, Andrew ; Qian, Christina ; Fabry-Vendrand, Caroline ; Touboul, Chantal ; Brzostek, Dorota ; Maslova, Ekaterina ; Surmont, Filip ; Goike, Helena ; Gandhi, Hitesh ; Korevaar, J.C. ; Tkacz, Joseph ; Johnston, Karissa ; Peres da Costa, Keith ; van Dijk, L. ; Vervloet, M. ; Pollack, Michael ; Hernandez, Paul ; Boarino, S. ; Noorduyn, Stephen G. ; Beekman-Hendricks, Wendy ; Weesie, Y.M. ; Universitat Autònoma de Barcelona
Expert national/global asthma management recommendations raise the issue whether a safe threshold of short-acting beta-2 agonist (SABA) use without concomitant inhaled corticosteroids (ICS) exists. To examine SABA and maintenance therapy associations with severe asthma exacerbations across North America and Europe. [...]
2022 - 10.1016/j.jaip.2022.02.047
Journal of Allergy and Clinical Immunology: In Practice, Vol. 10 Núm. 9 (september 2022) , p. 2297-2309.e10  

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