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8 p, 284.9 KB |
Acute Bacterial Meningitis in Healthy Adult Patients : A Prospective Cohort Study
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Pomar, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
Benito, Natividad (Institut d'Investigació Biomèdica Sant Pau) ;
Duch Llorach, Pol (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Colomé, Marc (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rivera, Alba (Institut d'Investigació Biomèdica Sant Pau) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Spontaneous bacterial meningitis (BM) is more common among patients with underlying conditions, but its characteristics in previously healthy patients are not well described. We analyzed the time trends of BM in terms of characteristics, and outcomes in patients without comorbidities. [...]
2023 -  10.3390/jcm12113624
Journal of clinical medicine, Vol. 12, Num. 11 (may 2023)
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12 p, 1006.3 KB |
Association between the Immunophenotype of Peripheral Blood from mCRPC Patients and the Outcomes of Radium-223 Treatment
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Cantó, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ;
Anguera, Georgia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Jiménez, Natalia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mellado, Begoña (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ramírez, Ona (Institut d'Investigació Biomèdica Sant Pau) ;
Mariscal, Anaís (Institut d'Investigació Biomèdica Sant Pau) ;
Maroto Rey, Pablo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
(1) Background: Prostate cancer is the second most common cancer in men, with androgen suppression as the standard treatment. Despite initially responding to castration, most metastatic prostate cancer patients eventually experience progression. [...]
2023 - 10.3390/diagnostics13132222
Diagnostics, Vol. 13, Num. 13 (june 2023)
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4 p, 257.0 KB |
Clinical Consequences of the Overuse of Short-Acting β2-Adrenergic Agonists (SABA) in the Treatment of Asthma in Spain : The SABINA Study
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Molina, Jesús (CS Francia, Dirección Asistencial Oeste, Fuenlabrada) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
Nuevo, Javier (Medical Department, AstraZeneca, Madrid) ;
Gutiérrez, Martín (Medical Department, AstraZeneca, 28033 Madrid) ;
Sicras-Mainar, Antoni (Health Economics and Outcomes Research, Atrys Health, Badalona) ;
Valero, Antonio (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
2023 - 10.1016/j.opresp.2023.100232
Open Respiratory Archives, Vol. 5, Num. 2 (january 2023)
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15 p, 3.6 MB |
Red Blood Cells and Endothelium Derived Circulating Extracellular Vesicles in Health and Chronic Heart Failure : A Focus on Phosphatidylserine Dynamics in Vesiculation
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Suades, Rosa (Institut d'Investigació Biomèdica Sant Pau) ;
Vilella-Figuerola, Alba (Institut d'Investigació Biomèdica Sant Pau) ;
Padró, Teresa (Institut d'Investigació Biomèdica Sant Pau) ;
Mirabet Pérez, Sonia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Circulating extracellular microvesicles (cEVs) are characterised by presenting surface antigens of parental cells. Since their biogenesis involves the translocation of phosphatidylserine (PS) from the inner to the outer leaflet of the plasma membrane, exposed PS has been considered as a recognition hallmark of cEVs. [...]
2023 - 10.3390/ijms241411824
International journal of molecular sciences, Vol. 24, Num. 14 (july 2023)
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19 p, 2.8 MB |
Consensus recommendations for the treatment and management of patients with Fabry disease on migalastat : a modified Delphi study
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Bichet, Daniel G. (University of Montréal, Canada) ;
Hopkin, Robert J. (University of Cincinnati College of Medicine, United States) ;
Aguiar, Patrício (Lisbon University) ;
Allam, Sridhar R. (Texas Christian University, Fort Worth, United States) ;
Chien, Yin-Hsiu (National Taiwan University College of Medicine, Taipei, Taiwan) ;
Giugliani, Roberto (Postgraduate Program in Genetics and Molecular Biology (PPGBM) at Federal University of Rio Grande do Sul (UFRGS), Porto Alegre, Brazil) ;
Kallish, Staci (University of Pennsylvania, Philadelphia, United States) ;
Kineen, Sabina (Patient Advocate, United States) ;
Lidove, Olivier (French Network of Inherited Metabolic Disorders (G2m), France) ;
Niu, Dau-Ming (National Yang Ming Chiao Tung University, Taipei, Taiwan) ;
Olivotto, Iacopo (Meyer University Children's Hospital, Florence, Italy) ;
Politei, Juan (Fundacion Para el Estudio de Enfermedades Neurometabolicas (FESEN), Buenos Aires, Argentina) ;
Rakoski, Paul (Patient Advocate, United States) ;
Torra Balcells, Roser (Institut d'Investigació Biomèdica Sant Pau) ;
Tøndel, Camilla (University of Bergen, Norway) ;
Hughes, Derralynn A. (Royal Free London NHS Foundation Trust and University College London, United Kingdom) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Fabry disease is a progressive disorder caused by deficiency of the α-galactosidase A enzyme (α-Gal A), leading to multisystemic organ damage with heterogenous clinical presentation. The addition of the oral chaperone therapy migalastat to the available treatment options for Fabry disease is not yet universally reflected in all treatment guidelines. [...]
2023 - 10.3389/fmed.2023.1220637
Frontiers in Medicine, Vol. 10 (september 2023)
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10 p, 715.9 KB |
Influence of body mass index on recurrence of atrial fibrillation after electrical cardioversion
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Ligero, Carmen (Hospital Universitari de Sant Joan, Universitat Rovira i Virgili) ;
Bazán, Víctor (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Guerra, José Maria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Rodríguez-Mañero, Moisés (Hospital Clínico Universitario de Santiago, Santiago de Compostela) ;
Viñolas, Xavier (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Alegret i Colomé, Josep Maria (Hospital Universitari de Sant Joan, Universitat Rovira i Virgili) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Several studies have shown an independent relationship between body mass index (BMI) and the incidence of atrial fibrillation (AF). However, little is known about the influence of BMI on AF recurrence after electrical cardioversion (ECV). [...]
2023 - 10.1371/journal.pone.0291938
PloS one, Vol. 18 (september 2023)
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10 p, 531.5 KB |
Expert consensus on the use of systemic glucocorticoids for managing eosinophil-related diseases
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Del Pozo, Victoria (Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD)) ;
Bobolea, Irina (Hospital Clínic i Provincial de Barcelona) ;
Rial, Manuel J. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES)) ;
Espigol-Frigolé, Georgina (Hospital Clínic i Provincial de Barcelona) ;
Solans, Roser (Hospital Universitari Vall d'Hebron) ;
Hernández Rivas, Jesús María (Hospital Universitario de Salamanca) ;
Mora, Elvira (La Fe University and Polytechnic Hospital) ;
Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau) ;
Izquierdo Alonso, José Luis (Guadalajara University Hospital) ;
Domínguez Sosa, María Sandra (University Hospital of Gran Canaria Dr. Negrín) ;
Maza-Solano, Juan (University Hospital, Sevilla) ;
Atienza-Mateo, Belén (Instituto de Investigación Marqués de Valdecilla (IDIVAL)) ;
Bañas-Conejero, David (Specialty Care Medical Department, GSK) ;
Moure, Abraham L. (Specialty Care Medical Department, GSK) ;
Rua Figueroa, Íñigo (University Hospital of Gran Canaria Dr. Negrín) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Eosinophil-related diseases represent a group of pathologic conditions with highly heterogeneous clinical presentation and symptoms ranging from mild to critical. Both systemic and localized forms of disease are typically treated with glucocorticoids. [...]
2024 - 10.3389/fimmu.2023.1310211
Frontiers in immunology, Vol. 14 (january 2024)
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10 p, 673.5 KB |
Treatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors : A Retrospective, Multinational, Multicentre Study
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Torres, Tiago (University of Porto, Portugal) ;
Chiricozzi, Andrea (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lé, Ana Maria (Centro Académico Clínico ICBAS - CHP, Porto, Portugal) ;
Marzano, Angelo Valerio (Università degli Studi di Milano, Italy) ;
Dapavo, Paolo (University of Turin, Italy) ;
Dauden, Esteban (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP), Madrid) ;
Carrascosa, Jόse-Manuel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lazaridou, Elizabeth (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Duarte, Gleison (Instituto Bahiano de Imunoterapias-IBIS, Salvador, Brazil) ;
Carvalho, André V. E. (Hospital Moinhos de Vento, Porto Alegre, Brazil) ;
Romiti, Ricardo (University of São Paulo, Brazil) ;
Rompoti, Natalia (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Teixeira, Laetitia (Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Portugal) ;
Abreu, Miguel (University of Porto, Portugal) ;
Ippoliti, Elena (Università Cattolica del Sacro Cuore, Rome, Italy) ;
Maronese, Carlo Alberto (Università degli Studi di Milano, Italy) ;
Llamas-Velasco, Mar (Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria de La Princesa (IIS-IP)) ;
Vilarrasa-Rull, Eva (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
del Alcázar, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Daponte, Athina-Ioanna (Aristotle University School of Medicine, Thessaloniki, Greece) ;
Papoutsaki, Marina (University of Athens, 'A. Sygros' Hospital for Skin and Venereal Diseases, Athens, Greece) ;
Carugno, Andrea (ASST Papa Giovanni XXIII, Bergamo, Italy) ;
Bellinato, Francesco (University Hospital of Verona, Italy) ;
Gisondi, Paolo (University Hospital of Verona, Italy) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Tuberculosis has a major global impact. Immunocompetent hosts usually control this disease, resulting in an asymptomatic latent tuberculosis infection (LTBI). Because TNF inhibitors increase the risk of tuberculosis reactivation, current guidelines recommend tuberculosis screening before starting any biologic drug, and chemoprophylaxis if LTBI is diagnosed. [...]
2024 - 10.1007/s40257-024-00845-4
American Journal of Clinical Dermatology, Vol. 25, Num. 2 (march 2024) , p. 333-342
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16 p, 1.2 MB |
Brodalumab Versus Guselkumab in Patients with Moderate-to-Severe Psoriasis with an Inadequate Response to Ustekinumab : A Randomized, Multicenter, Double-Blind Phase 4 Trial (COBRA)
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Reich, Kristian (University Medical Center Hamburg-Eppendorf, Hamburg, Germany) ;
Bianchi, Luca (U.O.S.D. di Dermatologia Fondazione PTV Policlinico Tor Vergata, Rome, Italy) ;
Khemis, Abdallah (Polyclinique Saint George, Groupe KANTYS, Nice, France) ;
Maul, Julia-Tatjana (University of Zürich) ;
Tsianakas, Athanasios (Fachklinik Bad Bentheim, Bad Bentheim, Germany) ;
Schempp, Christoph M. (University of Freiburg, Germany) ;
Petersen, Kim (LEO Pharma A/S, Ballerup, Denmark) ;
Noergaard, Mia M. (LEO Pharma A/S, Ballerup, Denmark) ;
Puig Sanz, Lluís (Hospital de la Santa Creu i Sant Pau) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Despite improved treatment options for plaque psoriasis within the last decades, some patients still have an inadequate response to treatment. Direct clinical evaluation between therapies used after biologic failure could facilitate physicians' choice of treatment. [...]
2024 - 10.1007/s13555-023-01092-x
Dermatology and Therapy, Vol. 14 (february 2024) , p. 453-468
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