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Neuropeptide-S-receptor deficiency affects sex-specific modulation of safety learning by pre-exposure to electric stimuli / Kreutzmann, Judith.C. (Department of Systems Physiology of Learning. Leibniz Institute for Neurobiology) ; Khalil, Radwa (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ; Köhler, Jana C. (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences) ; Mayer, Dana (Otto-von-Guericke University Magdeburg. Institute for Pharmacology & Toxicology) ; Florido Torres, Antonio Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Andero Galí, Raül (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Fendt, Markus (Otto-von-Guericke University Magdeburg. Center of Behavioral Brain Sciences)
Neuropeptide S (NPS) is a neuropeptide involved in the regulation of fear. Because safety learning is impaired in patients suffering from anxiety-related psychiatric disorders, and polymorphisms of the human neuropeptide S receptor (NPSR) gene have also been associated with anxiety disorders, we wanted to investigate whether NPSR-deficiency interferes with safety learning, and how prior stress would affect this type of learning. [...]
2020 - DOI (Digital Object Identifier)

10.1111/gbb.12621
Genes, Brain and Behavior, Vol. 19 Núm. 3 (January 2020) , p. e12621

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