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11 p, 870.1 KB |
Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder : results from the ENIGMA MDD Working Group
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Leerssen, Jeanne (Vrije Universiteit Amsterdam) ;
Blanken, Tessa F (Vrije Universiteit Amsterdam) ;
Pozzi, Elena (The National Centre of Excellence in Youth Mental Health) ;
Jahanshad, Neda (University of Southern California) ;
Aftanas, Lyubomir (Novosibirsk State University) ;
Andreassen, Ole A (University of Oslo) ;
Baune, Bernhard T. (The University of Melbourne) ;
Brak, Ivan (Scientific Research Institute of Neuroscience & Medicine) ;
Carballedo, Angela (Trinity College Dublin) ;
Ching, Christopher R. K (University of Southern California) ;
Dannlowski, Udo (University of Münster) ;
Dohm, Katharina (University of Münster) ;
Enneking, Verena (University of Münster) ;
Filimonova, Elena (Scientific Research Institute of Neuroscience & Medicine) ;
Fingas, Stella M. (University of Münster) ;
Frodl, Thomas (Otto von Guericke University Magdeburg) ;
Godlewska, Beata R. (University of Oxford) ;
Goltermann, Janik (University of Münster) ;
Gotlib, Ian H. (Stanford University) ;
Grotegerd, Dominik (University of Münster) ;
Gruber, Oliver (Heidelberg University) ;
Harris, Mathew A. (University of Edinburgh) ;
Hatton, Sean N. (University of Sydney) ;
Hawkins, Emma (University of Edinburgh) ;
Hickie, Ian B. (University of Sydney) ;
Jaworska, Natalia (University of Ottawa) ;
Kircher, Tilo (Philipps-University Marburg) ;
Krug, Axel (University of Bonn) ;
Lagopoulos, Jim (Sunshine Coast Mind and Neuroscience Thompson Institute) ;
Lemke, Hannah (University of Münster) ;
Li, Meng (Max Planck Institute for Biological Cybernetics) ;
MacMaster, Frank P. (Strategic Clinical Network for Addictions and Mental Health) ;
McIntosh, Andrew M. (University of Edinburgh) ;
McLellan, Quinn (University of Alberta) ;
Meinert, Susanne (University of Münster) ;
Mwangi, Benson (University of Texas Health Science Center at Houston) ;
Nenadić, Igor (Philipps-University Marburg) ;
Osipov, Evgeny (Scientific Research Institute of Neuroscience & Medicine) ;
Portella Moll, Maria Jesús (Institut d'Investigació Biomèdica Sant Pau) ;
Redlich, Ronny (University of Halle) ;
Repple, Jonathan (University of Münster) ;
Sacchet, Matthew D. (Harvard Medical School) ;
Sämann, Philipp G. (Max Planck Institute of Psychiatry) ;
Simulionyte, Egle (Heidelberg University) ;
Soares, Jair C. (University of Texas Health Science Center at Houston) ;
Walter, Martin (University of Tübingen) ;
Watanabe, Norio (Kyoto University) ;
Whalley, Heather (University of Edinburgh) ;
Yüksel, Dilara (SRI International) ;
Veltman, Dick J. (Amsterdam UMC. University Medical Center) ;
Thompson, Paul M. (University of Southern California) ;
Schmaal, Lianne (The University of Melbourne) ;
Van Someren, Eus J.W. (VU University) ;
Universitat Autònoma de Barcelona
It has been difficult to find robust brain structural correlates of the overall severity of major depressive disorder (MDD). We hypothesized that specific symptoms may better reveal correlates and investigated this for the severity of insomnia, both a key symptom and a modifiable major risk factor of MDD. [...]
2020 -  10.1038/s41398-020-01109-5
Translational psychiatry, Vol. 10 Núm. 1 (december 2020) , p. 425
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15 p, 2.0 MB |
White matter disturbances in major depressive disorder : a coordinated analysis across 20 international cohorts in the ENIGMA MDD working group
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van Velzen, Laura S. (The University of Melbourne. Centre for Youth Mental Health) ;
Kelly, Sinead (Harvard Medical School) ;
Isaev, Dmitry (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ;
Aleman, André (University of Groningen. Cognitive Neuroscience Center, University Medical Center Groningen) ;
Aftanas, Lybomir (Novosibirsk State University. Department of Neuroscience) ;
Bauer, Jochen (University of Münster, Institute of Clinical Radiology, Münster, Germany) ;
Baune, Bernhard T. (The University of Melbourne, Melbourne. The Florey Institute of Neuroscience and Mental Heatlh) ;
Brak, Ivan (Novosibirsk State University. Lab. of Experimental & Translational Neuroscience) ;
Carballedo, Angela (North Dublin Mental Health Services, Dublin, Ireland) ;
Connolly, Colm G. (Florida State University. Department of Biomedical Sciences) ;
Couvy-Duchesne, Baptiste (The University of Queensland. Institute for Molecular Bioscience) ;
Cullen, Kathryn R. (The University of Minnesota. Department of Psychiatry and Behavioral Sciences) ;
Danilenko, Konstantin V. (FSSBI "Scientific Research Institute of Physiology & Basic Medicine", Laboratory of Affective, Cognitive & Translational Neuroscience, Novosibirsk, Russia) ;
Dannlowski, Udo (University of Münster. Department of Psychiatry) ;
Enneking, Verena (University of Münster. Department of Psychiatry) ;
Filimonova, Elena (FSSBI "Scientific Research Institute of Physiology & Basic Medicine", Laboratory of Affective, Cognitive & Translational Neuroscience, Novosibirsk, Russia) ;
Förster, Katharina (University of Münster. Department of Psychiatry) ;
Frodl, Thomas (German Center for Neurodegenerative Disease, Magdeburg, Germany) ;
Gotlib, Ian H. (Stanford University. Department of Psychology) ;
Groenewold, Nynke A. (Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands) ;
Grotegerd, Dominik (University of Münster. Department of Psychiatry) ;
Harris, Mathew A. (University of Edinburgh. Division of Psychiatry) ;
Hatton, Sean N. (University of Sydney. Youth Mental Health Team, Brain and Mind Centre) ;
Hawkins, Emma L. (University of Edinburgh. Division of Psychiatry) ;
Hickie, Ian B. (University of Sydney. Youth Mental Health Team, Brain and Mind Centre) ;
Ho, Tiffany C. (Stanford University. Department of Psychiatry & Behavioral Sciences) ;
Jansen, Andreas (University of Marburg. Department of Psychiatry) ;
Kircher, Tilo (University of Marburg. Department of Psychiatry) ;
Klimes-Dougan, Bonnie (The University of Minnesota. Department of Psychology) ;
Kochunov, Peter (University of Maryland School of Medicine. Maryland Psychiatric Research Center, Department of Psychiatry) ;
Krug, Axel (University of Marburg. Department of Psychiatry) ;
Lagopoulos, Jim (Sunshine Coast Mind and Neuroscience-Thompson Institute, Birtinya, QLD Australia) ;
Lee, Renick (Institute of Mental Health. Research Division) ;
Lett, Tristram A. (Humboldt-Universität zu Berlin) ;
Li, Meng (University of Magdeburg. Department of Neurology) ;
MacMaster, Frank P. (Strategic Clinical Network for Addictions and Mental Health, Calgary, Canada) ;
Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
McIntosh, Andrew M.. (University of Edinburgh. Centre for Cognitive Ageing and Cognitive Epidemiology) ;
McLellan, Quinn (Alberta Children's Hospital Research Institute) ;
Meinert, Susanne (University of Münster. Department of Psychiatry) ;
Nenadić, Igor (University of Marburg. Department of Psychiatry) ;
Osipov, Evgeny (Novosibirsk State University. Lab. of Experimental & Translational Neuroscience) ;
Penninx, Brenda W. J. H. (Department of Psychiatry, Amsterdam UMC, The Netherlands) ;
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau) ;
Repple, Jonathan (University of Münster. Department of Psychiatry) ;
Roos, Annerine (Stellenbosch University. SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry) ;
Sacchet, Matthew D. (Harvard Medical School) ;
Sämann, Philipp G. (Max Planck Institute of Psychiatry) ;
Schnell, Knut (University of Heidelberg. Department of Psychiatry) ;
Shen, Xueyi (University of Edinburgh. Division of Psychiatry) ;
Sim, Kang (Nanyang Technological University. Lee Kong Chian School of Medicine) ;
Stein, Dan J. (SAMRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry & Neuroscience Institute, University of Cape Town, South Africa) ;
van Tol, Marie-José (University of Groningen. Cognitive Neuroscience Center) ;
Tomyshev, Alexander S. (Mental Health Research Center, Moscow, Russia) ;
Tozzi, Leonardo (Stanford University. Department of Psychiatry & Behavioral Sciences) ;
Veer, Ilya M. (Humboldt-Universität zu Berlin) ;
Vives-Gilabert, Yolanda (Universitat Politècnica de València. Instituto ITACA) ;
Walter, Henrik (Humboldt-Universität zu Berlin) ;
Walter, Martin (University of Tübingen. Department of Psychiatry and Psychotherapy) ;
van der Wee, Nic J. A. (Leiden University Medical Center. Department of Psychiatry) ;
van der Werff, Steven J. A. (Leiden University Medical Center. Department of Psychiatry) ;
Schreiner, Melinda Westlund (The University of Minnesota. Department of Psychology) ;
Whalley, Heather (University of Edinburgh. Division of Psychiatry) ;
Wright, Margaret J. (The University of Queensland. Centre for Advanced Imaging) ;
Yang, Tony T. (University of California. Department of Psychiatry) ;
Zhu, Alyssa (University of Southern California. Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine) ;
Veltman, Dick J. (Amsterdam Neuroscience) ;
Thompson, Paul M. (University of Southern California. Imaging Genetics Center) ;
Jahanshad, Neda (University of Southern California. Imaging Genetics Center) ;
Schmaal, Lianne (The University of Melbourne. Centre for Youth Mental Health) ;
Universitat Autònoma de Barcelona
Alterations in white matter (WM) microstructure have been implicated in the pathophysiology of major depressive disorder (MDD). However, previous findings have been inconsistent, partially due to low statistical power and the heterogeneity of depression. [...]
2019 - 10.1038/s41380-019-0477-2
Molecular psychiatry, Vol. 25 (august 2019) , p. 1511-1525
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