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Levodopa-carbidopa intestinal gel in advanced Parkinson's : Final results of the GLORIA registry
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Antonini, Angelo (University of Padua) ;
Poewe, Werner (Medical University of Innsbruck) ;
Chaudhuri, K.Ray (King's College and King's College Hospital) ;
Jech, Robert (General University Hospital in Prague) ;
Pickut, Barbara (Michigan State University) ;
Pirtošek, Zvezdan (University Medical Center Ljubljana) ;
Szasz, Jozsef (University of Medicine and Pharmacy Tirgu-Mures) ;
Valldeoriola, Francesc (Hospital Clínic i Provincial de Barcelona) ;
Winkler, Christian (Lindenbrunn Hospital) ;
Bergmann, Lars (AbbVie Inc.) ;
Yegin, Ashley (AbbVie Inc.) ;
Onuk, Koray (AbbVie Inc.) ;
Barch, David (AbbVie Inc.) ;
Odin, Per (Lund University) ;
Amalia, Ene (University Emergency Hospital) ;
Arnold, Guy (Sindelfingen Hospital) ;
Bajenaru, Ovidiu (University of Medicine and Pharmacy "Carol Davila") ;
Bergmans, Bruno (AZ St-Jan Brugge-Oostende AV) ;
Bjornara, Kari Anne (Drammen Hospital) ;
Blackie, Jeff (John Hunter Hospital) ;
Bode, Matthias (Odense University Hospital (Dinamarca)) ;
Bourgeois, Paul (Department of Neurology AZ Groeninge) ;
Bohlhalter, Stephan (Neurology and Neurorehabilitation Center) ;
Buraga, Ioan (Colentina Hospital) ;
Burkhard, Pierre R. (Geneva University Hospitals) ;
Busson, Philippe (Centre Hospitalier Avranches Granvilles) ;
Calopa, Matilde (Hospital Universitari de Bellvitge) ;
Clausen, Jesper (Rigshospitalet/Glostup) ;
Danielsen, Erik Hvid (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Defebvre, Luc (Université of Lille) ;
Delvaux, Valerie (University of Liege) ;
Dethy, Sophie (Chu-Tivoli) ;
Dietrichs, Espen (University of Oslo) ;
Fàbregues-Boixar i Nebot, Oriol de (Hospital Universitari Vall d'Hebron) ;
Gerhard, Ransmayr (Kepler University Hospital) ;
Gusmaroli, Graziano (Ospedale degli Infermi di Biella) ;
Hahn, Kirsten ;
Hauptmann, Björn (Neurologisches Zentrum) ;
Henriksen, Tove (University Hospital of Bispebjerg) ;
Hernández-Vara, Jorge (Hospital Universitari Vall d'Hebron) ;
Jeanjean, A. (Université catholique de Louvain) ;
Kaiserova, Michaela (Palacky University) ;
Kassubek, Jan (University of Ulm) ;
Kimber, Thomas (University of Adelaide) ;
Konitsiotis, Spyridon (University of Ioannina) ;
Krüger, Rejko (University of Tübingen) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Leenders, Jo (Sint-Dimpa Ziekenhuis) ;
Lundqvist, Christofer (Akershus University Hospital) ;
Ory Magne, F. (Toulouse University Hospital) ;
Marano, Pietro (Nuova Casa di Cura D'Anna) ;
Milanov, Ivan (University Neurological Hospital "St. Naum") ;
Modugno, Nicola (IRCCS Neuromed) ;
Misbahuddin, Anjum (Essex Centre for Neurological Sciences) ;
Nevrly, Martin (University Hospital and Faculty of Medicine and Dentistry of Palacky University) ;
Panayiotis, Zikos (251 Hellenic Air Force Hospital) ;
Pedersen, Kenn Freddy (Stavanger University Hospital) ;
Pedersen, Stephen W. (Glostrup Hospital University of Copenhagen) ;
Perju-Dumbrava, Lacramioara (University of Medicine and Pharmacy "Iuliu Hatieganu") ;
Ponsen, M.M. (Meander Medical Center) ;
Popescu, Bogdan O. (Carol Davila University of Medicine and Pharmacy) ;
Rijntjes, Michel (University Clinic Freiburg) ;
Puente, V. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Redecker, Christoph (Jena University Hospital (Alemania)) ;
Schrader, Christoph (Hannover Medical School) ;
Sensi, Mariachiara (Arcispedale S.Anna) ;
Simu, Michaela (UMF"Victor Babes") ;
Spanaki, Cleanthe (University of Crete) ;
Storch, Alexander (University of Rostock) ;
Storstein, Anette (Haukeland University Hospital (Bergen, Noruega)) ;
Tomantschger, Volker (Gailtal-Klinik Hermagor) ;
van der Linden, Chris (St. Lucas Hospital Ghent) ;
van Laar, T. (University Medical Center Groningen) ;
Viallet, F. (CH du pays d'Aix) ;
Witjas, Tatiana (University Hospital Timone) ;
Wolz, Martin (Elblandklinikum Meissen) ;
Zibetti, Maurizio (University of Torino) ;
Van Zandijcke, Michel (AZ Sint-Jan Brugge) ;
Universitat Autònoma de Barcelona
This registry evaluated the 24-month safety and efficacy of levodopa-carbidopa intestinal gel (LCIG) treatment in advanced Parkinson's disease (PD) patients under routine clinical care. Motor fluctuations, dyskinesia, non-motor symptoms, quality of life, and safety were evaluated. [...]
2017 -  10.1016/j.parkreldis.2017.09.018
Parkinsonism and Related Disorders, Vol. 45 (december 2017) , p. 13-20
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Identification of sixteen novel candidate genes for late onset Parkinson's disease
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Gialluisi, Alessandro (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Reccia, Mafalda Giovanna (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Modugno, Nicola (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Nutile, Teresa (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Lombardi, Alessia (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Di Giovannantonio, Luca Giovanni (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Pietracupa, Sara (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Ruggiero, Daniela (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Scala, Simona (IRCCS Istituto Neurologico Mediterraneo Neuromed) ;
Gambardella, Stefano (Department of Biomolecular Science. University of Urbino Carlo Bò) ;
Noyce, Alastair J. ;
Kaiyrzhanov, Rauan ;
Middlehurst, Ben ;
Kia, Demis A. ;
Tan, Manuela ;
Houlden, Henry ;
Morris, Huw R. ;
Plun-Favreau, Helen ;
Holmans, Peter ;
Hardy, John ;
Trabzuni, Daniah ;
Quinn, John ;
Bubb, Vivien ;
Mok, Kin Y. ;
Kinghorn, Kerri J. ;
Billingsley, Kimberley ;
Wood, Nicholas W.. ;
Lewis, Patrick ;
Schreglmann, Sebastian ;
Lovering, Rruth ;
R'Bibo, Lea ;
Manzoni, Claudia ;
Rizig, Mie ;
Ryten, Mina ;
Guelfi, Sebastian ;
Escott-Price, Valentina ;
Chelban, Viorica ;
Foltynie, Thomas ;
Williams, Nigel ;
Morrison, Karen E. ;
Clarke, Carl ;
Brice, Alexis ;
Danjou, Fabrice ;
Lesage, Suzanne ;
Corvol, Jean-Christophe ;
Martinez Rande, Maria (INSERM UMR 1220) ;
Schulte, Claudia ;
Brockmann, Kathrin ;
Simón-Sánchez, Javier ;
Heutink, Peter ;
Rizzu, Patrizia ;
Sharma, Manu ;
Gasser, Thomas ;
Cookson, Mark R. ;
Bandres-Ciga, Sara ;
Blauwendraat, Cornelis ;
Craig, David W. ;
Narendra, Derek ;
Faghri, Faraz ;
Gibbs, J.Raphael ;
Hernandez, Dena G. ;
Van Keuren-Jensen, Kendall ;
Shulman, Joshua M. ;
Iwaki, Hirotaka ;
Leonard, Hampton L. ;
Nalls, Mike A. ;
Robak, Laurie ;
Bras, Jose ;
Guerreiro, Rita ;
Lubbe, Steven ;
Finkbeiner, Steven ;
Mencacci, Niccolo E. ;
Lungu, Codrin ;
Singleton, Andrew B. ;
Scholz, Sonja ;
Reed, Xylena ;
Alcalay, Roy N. ;
Gan-Or, Zin ;
Rouleau, Guy A. ;
Krohn, Lynne ;
van Hilten, Jacobus J. ;
Marinus, Johan ;
Adarmes-Gómez, A.D ;
Aguilar Barberà, Miquel ;
Alvarez, Ignacio (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Alvarez, Victoria ;
Barrero, Francisco Javier ;
Bergareche Yarza, Jesús Alberto ;
Bernal-Bernal, Inmaculada ;
Blázquez Estrada, Marta ;
Bonilla-Toribio, Marta ;
Botía, Juan A. ;
Boungiorno, María Teresa ;
Buiza-Rueda, Dolores ;
Carrillo, Fátima ;
Carrión-Claro, M ;
Cerdan, Debora ;
Clarimón, Jordi ;
Compta, Yaroslau ;
Diez-Fairen, Monica ;
Dols Icardo, Oriol ;
Duarte, Jacinto ;
Duran, Raquel ;
Escamilla Sevilla, Francisco ;
Ezquerra, Mario ;
Feliz, Cici ;
Fernández, Manel ;
Fernández-Santiago, Rubén ;
Garcia, Ciara ;
García-Ruiz, Pedro ;
Gómez-Garre, Pilar ;
Gomez Heredia, Maria Jose ;
Gonzalez-Aramburu, Isabel ;
Gorostidi Pagola, Ana ;
Hoenicka, Janet ;
Infante, Jon ;
Jesús, Silvia ;
Jiménez-Escrig, Adriano (Hospital General de Segovia) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Labrador-Espinosa, Miguel A. ;
Lopez-Sendon, Jose Luis ;
López de Munain Arregui, Adolfo ;
Macias, Daniel ;
Martínez Torres, Irene ;
Marín, Juan ;
Marti, Maria Jose ;
Martínez-Castrillo, Juan Carlos ;
Méndez-del-Barrio, Carlota ;
Menéndez González, Manuel ;
Mata, Marina ;
Mínguez, Adolfo ;
Mir, Pablo ;
Mondragon Rezola, Elisabet ;
Muñoz, Esteban ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Pastor, Pau ;
Perez Errazquin, Francisco ;
Periñán-Tocino, Teresa ;
Ruiz-Martínez, Javier ;
Ruz, Clara ;
Sanchez Rodriguez, Antonio ;
Sierra, María ;
Suarez-Sanmartin, Esther ;
Tabernero, Cesar ;
Tartari, Juan Pablo ;
Tejera-Parrado, Cristina ;
Tolosa, Eduard ;
Valldeoriola, Francesc ;
Vargas-González, Laura ;
Vela, Lydia ;
Vives, Francisco ;
Zimprich, Alexander ;
Pihlstrom, Lasse ;
Toft, Mathias ;
Koks, Sulev ;
Taba, Pille ;
Hassin-Baer, Sharon ;
Majamaa, Kari ;
Siitonen, Ari ;
Okubadejo, Njideka U. ;
Ojo, Oluwadamilola O. ;
Kaiyrzhanov, Rauan ;
Shashkin, Chingiz ;
Zharkynbekova, Nazira ;
Akhmetzhanov, Vadim ;
Aitkulova, Akbota ;
Zholdybayeva, Elena ;
Zharmukhanov, Zharkyn ;
Kaishybayeva, Gulnaz ;
Karimova, Altynay ;
Sadykova, Dinara ;
Iacoviello, Licia (University of Insubria (Itàlia)) ;
Gianfrancesco, F. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Acampora, D. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
D'Esposito, M. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Simeone, A. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Ciullo, M. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso") ;
Esposito, T. (National Research Council. Institute of Genetics and Biophysics "Adriano Buzzati-Traverso")
Background: Parkinson's disease (PD) is a neurodegenerative movement disorder affecting 1-5% of the general population for which neither effective cure nor early diagnostic tools are available that could tackle the pathology in the early phase. [...]
2021 - 10.1186/s13024-021-00455-2
Molecular neurodegeneration, Vol. 16 Núm. 1 (december 2021) , p. 35
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