Stitt, Alan W. - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

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Artículos, Encontrados 3 registros

Artículos	Encontrados 3 registros

19 p, 12.6 MB

Disruption of cortical cell type composition and function underlies diabetes-associated cognitive decline / Little, Karis (Queen's University Belfast) ; Singh, Aditi (Queen's University Belfast) ; Del Marco, Angel (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Llorián-Salvador, María (Hospital Universitari Vall d'Hebron) ; Vargas-Soria, Maria (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Turch-Anguera, Mireia (Hospital Universitari Vall d'Hebron) ; Solé Piñol, Montserrat (Hospital Universitari Vall d'Hebron) ; Bakker, Noëlle (Amsterdam UMC location University) ; Scullion, Sarah (Queen's University Belfast) ; Comella i Carnicé, Joan Xavier 1963- (Hospital Universitari Vall d'Hebron) ; Klaassen, Ingeborg (Amsterdam UMC location University of Amsterdam) ; Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron) ; Garcia-Alloza, Monica (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Tiwari, Vijay K. (Odense University Hospital (Dinamarca)) ; Stitt, Alan W. (Queen's University Belfast) ; Universitat Autònoma de Barcelona
Type 2 diabetes is associated with increased risk of cognitive decline although the pathogenic basis for this remains obscure. Deciphering diabetes-linked molecular mechanisms in cells of the cerebral cortex could uncover novel therapeutic targets. [...]
2023 - DOI (Digital Object Identifier)

10.1007/s00125-023-05935-2
Diabetologia, Vol. 66 (june 2023) , p. 1557-1575

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13 p, 3.6 MB

Accelerated amyloid angiopathy and related vascular alterations in a mixed murine model of Alzheimer's disease and type two diabetes / Vargas-Soria, Maria (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Ramos-Rodriguez, Juan Jose (Universidad de Granada) ; Del Marco, Angel (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Hierro-Bujalance, Carmen (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Carranza-Naval, Maria Jose (Universidad de Cádiz) ; Calvo-Rodriguez, Maria (Harvard Medical School) ; van Veluw, Susanne J. (Harvard Medical School) ; Stitt, Alan W. (Queen's University Belfast) ; Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bacskai, Brian J. (Harvard Medical School) ; Infante-Garcia, Carmen (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Garcia-Alloza, Monica (Instituto de Investigacion e Innovacion en Ciencias Biomedicas de la Provincia de Cadiz) ; Universitat Autònoma de Barcelona
While aging is the main risk factor for Alzheimer's disease (AD), emerging evidence suggests that metabolic alterations such as type 2 diabetes (T2D) are also major contributors. Indeed, several studies have described a close relationship between AD and T2D with clinical evidence showing that both diseases coexist. [...]
2022 - DOI (Digital Object Identifier)

10.1186/s12987-022-00380-6
Fluids and Barriers of the CNS, Vol. 19 (november 2022)

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11 p, 1.9 MB

Neurodegeneration in diabetic retinopathy : does it really matter? / Simó Canonge, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina) ; Stitt, Alan W. (Queen's University. Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences) ; Gardner, Thomas W. (Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medical School) ; Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol
The concept of diabetic retinopathy as a microvascular disease has evolved, in that it is now considered a more complex diabetic complication in which neurodegeneration plays a significant role. In this article we provide a critical overview of the role of microvascular abnormalities and neurodegeneration in the pathogenesis of diabetic retinopathy. [...]
2018 - DOI (Digital Object Identifier)

10.1007/s00125-018-4692-1
Diabetologia, Vol. 61 (july 2018) , p. 1902-1912

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