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18 p, 851.1 KB |
Clinical outcome measures in dementia with Lewy bodies trials : critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 -  10.1186/s40035-022-00299-w
Translational Neurodegeneration, Vol. 11 (may 2022)
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1 p, 574.4 KB |
Correction : Clinical outcome measures in dementia with Lewy bodies trials: critique and recommendations
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Rodriguez-Porcel, Federico (Medical University of South Carolina) ;
Wyman-Chick, Kathryn A. (HealthPartners) ;
Abdelnour, Carla (Universitat Autònoma de Barcelona) ;
Toledo, Jon B. (University of Florida) ;
Ferreira, Daniel (Mayo Clinic) ;
Urwyler, Prabitha (University of Bern) ;
Weil, Rimona S. (University College London) ;
Kane, Joseph (Queen's University) ;
Pilotto, Andrea (University of Brescia) ;
Rongve, Arvid (The University of Bergen) ;
Boeve, Bradley (Mayo Clinic) ;
Taylor, John-Paul (Newcastle University) ;
McKeith, Ian (Newcastle University) ;
Aarsland, Dag (King's College London) ;
Lewis, Simon J. G. (University of Sydney)
The selection of appropriate outcome measures is fundamental to the design of any successful clinical trial. Although dementia with Lewy bodies (DLB) is one of the most common neurodegenerative conditions, assessment of therapeutic benefit in clinical trials often relies on tools developed for other conditions, such as Alzheimer's or Parkinson's disease. [...]
2022 - 10.1186/s40035-022-00306-0
Translational Neurodegeneration, Vol. 11 (may 2022)
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15 p, 294.1 KB |
The reliability of a deep learning model in clinical out-of-distribution MRI data : A multicohort study
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Mårtensson, Gustav (Karolinska Institutet (Estocolm, Suècia)) ;
Ferreira, Daniel (Karolinska Institutet (Estocolm, Suècia)) ;
Granberg, Tobias (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Cavallin, Lena (Karolinska University Hospital and Karolinska Institutet (Suecia)) ;
Oppedal, Ketil (University of Stavanger) ;
Padovani, Alessandra (University of Brescia) ;
Rektorova, Irena (Masaryk University) ;
Bonanni, Laura (University G d'Annunzio of Chieti-Pescara) ;
Pardini, Matteo (University of Genoa and Neurology Clinics) ;
Kramberger, Milica G. (Univerza V Ljubljani) ;
Taylor, John-Paul (Newcastle University) ;
Hort, Jakub (Charles University) ;
Snædal, Jón (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frederic (University of Strasbourg and French National Centre for Scientific Research (CNRS)) ;
Antonini, Angelo (University of Padua) ;
Mecocci, Patrizia (University of Perugia) ;
Vellas, Bruno (University of Toulouse) ;
Tsolaki, Magda (3rd Aristotle University of Thessaloniki) ;
Kłoszewska, Iwona (Medical University of Lodz) ;
Soininen, H. (Kuopio University Hospital ( Finlàndia)) ;
Lovestone, S. (University of Oxford) ;
Simmons, A. (King's College London) ;
Aarsland, Dag (King's College London) ;
Westman, Eric (King's College London) ;
Universitat Autònoma de Barcelona
Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in medical imaging are often trained on public research cohorts with images acquired with a single scanner or with strict protocol harmonization, which is not representative of a clinical setting. [...]
2020 - 10.1016/j.media.2020.101714
Medical Image Analysis, Vol. 66 (december 2020) , p. 101714
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13 p, 637.2 KB |
Importance of Resolving Fungal Nomenclature: the Case of Multiple Pathogenic Species in the Cryptococcus Genus
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Hagen, Ferry (Canisius-Wilhelmina Hospital. Department of Medical Microbiology and Infectious Diseases) ;
Lumbsch, Thorsten (The Field Museum) ;
Arsic Arsenijevic, Valentina (University of Belgrade. Institute of Microbiology and Immunology) ;
Badali, Hamid (University of Medical Science. Department of Medical Mycology and Parasitology) ;
Bertout, Sebastien (Université Montpellier. Laboratoire de Parasitologie et Mycologie Médicale) ;
Blake Billmyre, R. (Duke University Medical Center. Department of Molecular Genetics and Microbiology) ;
Bragulat, M. Rosa (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Cabañes Sáenz, Francisco Javier (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Carbia, Mauricio (Universidad de la República. Departamento de Parasitología y Micología) ;
Chakrabarti, Arunaloke (Postgraduate Institute of Medical Education and Research) ;
Chaturvedi, Sudha (Mycology Laboratory. Wadsworth Center. New York State Department of Health) ;
Chaturvedi, Vishnu (Mycology Laboratory. Wadsworth Center. New York State Department of Health) ;
Chen, Min (Second Military Medical University. Shanghai Key Laboratory of Molecular Medical Mycology) ;
Chowdhary, Anuradha (University of Delhi. Department of Medical Mycology) ;
Colom, Maria-Francisca (Universidad Miguel Hernández de Elche. Facultad de Medicina) ;
Cornely, Oliver A. (University of Cologne. CECAD Cluster of Excellence) ;
Crous, Pedro W. (Westerdijk Fungal Biodiversity Institute. Utrecht. Phytopathology Research) ;
Cuétara, Maria S. (Hospital Universitario Severo Ochoa) ;
Diaz, Mara R. (University of Miami. NSF NIEHS Oceans and Human Health Center) ;
Espinel-Ingroff, Ana (VCU Medical Center. Richmond) ;
Fakhim, Hamed (Urmia University of Medical Sciences. Department of Medical Parasitology and Mycology) ;
Falk, Rama (Hadassah-Hebrew University Medical Center. Department of Clinical Microbiology and Infectious Diseases) ;
Fang, Wenjie (Second Military Medical University. Shanghai Key Laboratory of Molecular Medical) ;
F. Herkert, Patricia (Canisius-Wilhelmina Hospital. Department of Medical Microbiology and Infectious Diseases) ;
Ferrer Rodríguez, Consuelo (Universidad Miguel Hernández de Elche. Facultad de Medicina) ;
Fraser, James A. (University of Queensland. Australian Infectious Diseases Research Centre) ;
Gené, Josepa (Universitat Rovira i Virgili. Unitat de Micologia) ;
Guarro Artigas, Josep (Universitat Rovira i Virgili. Unitat de Micologia) ;
Idnurm, Alexander (University of Melbourne) ;
Illnait-Zaragozi, María Teresa (Tropical Medicine Institute Pedro Kouri. Department of Bacteriology and Mycology) ;
Khan, Ziauddin (Kuwait University. Department of Microbiology) ;
Khayhan, Kantarawee (University of Phayao. Department of Microbiology and Parasitology) ;
Kolecka, Anna (Westerdijk Fungal Biodiversity Institute. Yeast Research) ;
Kurtzman, Cletus P. (National Center for Agricultural Utilization Research. Mycotoxin Prevention and Applied Microbiology Research Unit) ;
Lagrou, Katrien (University Hospitals Leuven (Bèlgica)) ;
Liao, Wanquing (Second Military Medical University. Shanghai Key Laboratory of Molecular Medical Mycology) ;
Linares, Carlos (Universidad Miguel Hernández de Elche. Facultad de Medicina) ;
Meis, Jacques F. (Canisius-Wilhelmina Hospital. Department of Medical Microbiology and Infectious Diseases) ;
Nielsen, Kirsten (University of Minnesota. Department of Microbiology and Immunology) ;
Nyazika, Tinashe K. (University of Zimbabwe. Department of Medical Microbiology) ;
Pan, Weihua (Second Military Medical University. Shanghai Key Laboratory of Molecular Medical Mycology) ;
Pekmezovic, Marina (University of Belgrade. Faculty of Medicine) ;
Polacheck, Itzhack (Hadassah-Hebrew University Medical Center. Department of Clinical Microbiology and Infectious Diseases) ;
Posteraro, Brunella (Università Cattolica del Sacro Cuore. Fondazione Policlinico Universitario Agostino Gemelli) ;
de Queiroz Telles Filho, Flavio (Universidade Federal do Paraná) ;
Romeo, Orazio (University of Messina. Department of Chemical, Biological, Pharmaceutical and Environmental Sciences) ;
Sánchez, Manuel (Universidad Miguel Hernández de Elche. Facultad de Medicina) ;
Sampaio, Ana (Universidade de Trás-os-Montes e Alto Douro (UTAD). Centro de Investigação e de Tecnologias Agro-ambientais e Biológicas (CITAB)) ;
Sanguinetti, Maurizio (Università Cattolica del Sacro Cuore. Institute of Microbiology) ;
Sriburee, Pojana (Chiang Mai University. Department of Microbiology) ;
Sugita, Takashi (Meiji Pharmaceutical University. Department of Microbiology) ;
Taj-Aldeen, Saad J. (Hamad Medical Corporation. Mycology Unit) ;
Takashima, Masako (RIKEN BioResource Center. Japan Collection of Microorganisms) ;
Taylor, John W. (University of California Berkeley. Department of Plant and Microbial Biology) ;
Theelen, Theelen (Westerdijk Fungal Biodiversity Institute. Yeast Research) ;
Tomazin, Rok (University of Ljubljana. Institute of Microbiology and Immunology) ;
Verweij, Paul E. (Radboud University Medical. Centre of Expertise in Mycology) ;
Wahyuningsih, Retno (Universitas Indonesia. Department of Parasitology) ;
Wang, Ping (Louisiana State University Health Sciences Center. Department of Microbiology, Immunology and Parasitology) ;
Boekhout, Teun (University of Amsterdam. Institute of Biodiversity and Ecosystems Dynamics (IBED))
Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and Cryptococcus neoformans species complexes. After more than 15 years of molecular genetic and phenotypic studies and much debate, a proposal for a taxonomic revision was made. [...]
2017 - 10.1128/mSphere.00238-17
mSphere, Vol. 2 Núm. 4 (Juliol/Agost 2017) , p. 1-13
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