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1.
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10 p, 396.0 KB |
Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events : The ODYSSEY OUTCOMES Trial
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Szarek, Michael (State University of New York) ;
White, Harvey D. (University of Auckland and Green Lane Cardiovascular Services Auckland City Hospital) ;
Schwartz, Gregory G. (Division of Cardiology. University of Colorado School of Medicine) ;
Alings, Marco (Amphia Ziekenhuis Molengracht) ;
Bhatt, Deepak L (Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School) ;
Bittner, Vera A. (University of Alabama at Birmingham) ;
Chiang, Chern-En (Taipei Veterans General Hospital and National Yang-Ming University) ;
Diaz, Rafael (Instituto Cardiovascular de Rosario) ;
Edelberg, Jay M. (Sanofi) ;
Goodman, Shaun G. (University of Toronto) ;
Hanotin, Corinne (Sanofi) ;
Harrington, R.A. (Stanford University) ;
Jukema, J.Wouter (Leiden University Medical Center) ;
Kimura, Takeshi (Kyoto University Graduate School of Medicine) ;
Kiss, Robert Gabor (Magyar Honvédség Egészségügyi Központ) ;
Lecorps, Guillaume (Sanofi) ;
Mahaffey, Kenneth W. (Stanford University) ;
Moryusef, Angèle (Sanofi) ;
Pordy, Robert (Regeneron Pharmaceuticals Inc.) ;
Roe, Matthew T. (Duke University Medical Center) ;
Tricoci, Pierluigi (Duke University Medical Center) ;
Xavier, Denis (St. John's Medical College and Research Institute) ;
Zeiher, Andreas Michael (Goethe University) ;
Steg, Ph Gabriel (Royal Brompton Hospital (Londres)) ;
Cequier Fillat, Angel R. (Hospital Universitari de Bellvitge) ;
Garcia-Dorado, David (Hospital Universitari Vall d'Hebron) ;
Matas Pericas, Laia (Institut d'Investigació Biomèdica Sant Pau) ;
Bruguera Cortada, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Gusi Tragant, Gabriel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Coca Payeras, Antonio (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
The ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab) trial compared alirocumab with placebo, added to high-intensity or maximum-tolerated statin treatment, after acute coronary syndrome (ACS) in 18,924 patients. [...]
2019 -  10.1016/j.jacc.2018.10.039
Journal of the American College of Cardiology, Vol. 73 Núm. 4 (may 2019) , p. 387-396
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2.
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10 p, 324.1 KB |
Alirocumab in Patients With Polyvascular Disease and Recent Acute Coronary Syndrome : ODYSSEY OUTCOMES Trial
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Jukema, J.Wouter (Leiden University Medical Center) ;
Szarek, Michael (State University of New York) ;
Zijlstra, Laurien E. (Leiden University Medical Center) ;
de Silva, H.Asita (University of Kelaniya) ;
Bhatt, Deepak L (Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School) ;
Bittner, Vera A. (University of Alabama at Birmingham) ;
Diaz, Rafael (Cardiovascular Institute of Rosario) ;
Edelberg, Jay M. (Sanofi) ;
Goodman, Shaun G. (St. Michael's Hospital. University of Toronto) ;
Hanotin, Corinne (Sanofi) ;
Harrington, Robert A. (Stanford University) ;
Karpov, Yuri (Russian Cardiological Scientific-Productive Complex) ;
Moryusef, Angèle (Sanofi) ;
Pordy, Robert (Regeneron Pharmaceuticals. Inc.) ;
Prieto, Juan C. (University of Chile Clinical Hospital) ;
Roe, Matthew T. (Duke University School of Medicine) ;
White, Harvey D. (Green Lane Cardiovascular Services Auckland City Hospital) ;
Zeiher, Andreas Michael (Goethe University) ;
Schwartz, Gregory G. (University of Colorado School of Medicine) ;
Steg, P.Gabriel (Royal Brompton Hospital (Londres)) ;
Cequier, Ángel (Hospital Universitari de Bellvitge) ;
García-Dorado, David (Hospital Universitari Vall d'Hebron) ;
Mata Pericas, Laia (Institut d'Investigació Biomèdica Sant Pau) ;
Bruguera Cortada, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Gusi Tragant, Gabriel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Coca Payeras, Antonio (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Patients with acute coronary syndrome (ACS) and concomitant noncoronary atherosclerosis have a high risk of major adverse cardiovascular events (MACEs) and death. The impact of lipid lowering by proprotein convertase subtilisin-kexin type 9 inhibition in such patients is undetermined. [...]
2019 - 10.1016/j.jacc.2019.03.013
Journal of the American College of Cardiology, Vol. 74 Núm. 9 (march 2019) , p. 1167-1176
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3.
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7 p, 3.0 MB |
Improving lipid management in patients with acute coronary syndrome : The ACS Lipid EuroPath tool
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Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ;
Catapano, Alberico L. (University of Milan) ;
De Ferrari, Gaetano M. (Azienda Ospedaliero Universitaria Città Della Salute e Della Scienza di Torino) ;
Dudek, Dariusz (Jagiellonian University Hospital) ;
Jukema, J. Wouter (Leiden University Medical Center) ;
Landmesser, Ulf (Charité University Medicine Berlin) ;
Pirillo, Angela (Bassini Hospital) ;
Schiele, François (CHU of Besançon) ;
Zaman, Azfar (Newcastle Upon Tyne Hospital NHS Foundation Trust) ;
Zamorano, Jose L. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Universitat Autònoma de Barcelona
Post-acute coronary syndrome (ACS) patients are at very high risk for recurrent events and mortality, despite the availability of effective pharmacological approaches. In 2018, the ACS EuroPath Survey, performed in collaboration with 555 European cardiologists, identified a sub-optimal LDL-C management in post-ACS patients. [...]
2020 - 10.1016/j.atherosclerosissup.2021.01.011
Atherosclerosis Supplements, Vol. 42 (december 2020) , p. e65-e71
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4.
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10 p, 1.1 MB |
Respiratory Polygraphy Patterns and Risk of Recurrent Cardiovascular Events in Patients With Acute Coronary Syndrome
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Zapater, Andrea (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Solelhac, Geoffroy (Lausanne University Hospital) ;
Sánchez-de-la-Torre, Alicia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Gracia-Lavedan, Esther (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Benitez, Ivan David (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Torres, Gerard (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
De Batlle, Jordi (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Haba-Rubio, José (Lausanne University Hospital) ;
Berger, Mathieu (Lausanne University Hospital) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Duran-Cantolla, Joaquín (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Urrutia, Amaia (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mediano, Olga (Hospital Universitario de Guadalajara) ;
Masdeu, María José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ordax-Carbajo, Estrella (Hospital Universitario de Burgos) ;
Masa, Juan Fernando (Hospital San Pedro de Alcántara) ;
De la Peña, Mónica (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Mayos, Mercè (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Coloma, Ramon (Complejo Hospitalario Universitario de Albacete) ;
Montserrat, Josep María (Hospital Clínic i Provincial de Barcelona) ;
Chiner, Eusebi (Hospital Universitari Sant Joan d'Alacant) ;
Mínguez, Olga (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Pascual, Lydia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Cortijo, Anunciación (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Martínez López, Dolores (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Dalmases, Mireia (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Lee, Chi-Hang (National University of Singapore) ;
McEvoy, R. Doug (Flinders University) ;
Barbé, Ferran (University of Lausanne) ;
Heinzer, Raphael (University of Lausanne) ;
Sánchez-de-la-Torre, Manuel (Hospital Universitari Arnau de Vilanova-Santa Maria) ;
Universitat Autònoma de Barcelona
Obstructive sleep apnea (OSA) severity is based on the apnea-hypopnea index (AHI). The AHI is a simplistic measure that is inadequate for capturing disease severity and its consequences in cardiovascular diseases (CVDs). [...]
2022 - 10.3389/fmed.2022.870906
Frontiers in Medicine, Vol. 9 (june 2022)
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13 p, 2.3 MB |
Coronary microvascular dysfunction in takotsubo syndrome assessed by angiography-derived index of microcirculatory resistance : A pressure-wire-free tool
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Sans-Roselló, Jordi (Section of Interventional Cardiology. MedStar Washington Hospital Center) ;
Fernández-Peregrina, Estefanía (Section of Interventional Cardiology, MedStar Washington Hospital Center) ;
Durán-Cambra, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Carreras-Mora, Jose (Hospital del Mar (Barcelona, Catalunya)) ;
Sionis, Alessandro (Institut d'Investigació Biomèdica Sant Pau) ;
Alvarez-Garcia, Jesus (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Garcia-Garcia, Héctor Manuel (Section of Interventional Cardiology. MedStar Washington Hospital Center) ;
Universitat Autònoma de Barcelona
Background: Coronary microvascular dysfunction (CMD) has been proposed as a key mechanism in Takotsubo syndrome (TTS). The non-hyperaemic angiography-derived index of microcirculatory resistance (NH-IMRangio) has been validated as a pressure-wire-free tool for the assessment of coronary microvasculature. [...]
2021 - 10.3390/jcm10194331
Journal of clinical medicine, Vol. 10 Núm. 19 (October 2021) , p. 4331
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11 p, 1.1 MB |
Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic : Time Series Analysis and Impact of Socioeconomic Factors
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Álvarez-Martín, Claudia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribera, A (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Marsal, Josep Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ariza-Solé, Albert (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Pérez-Hoyos, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Oristrell, Gerard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soriano-Colomé, Toni (Hospital Universitari Vall d'Hebron) ;
Romaguera, Rafael (Institut d'Investigació Biomèdica de Bellvitge) ;
Pijoan, Jose Ignacio (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Lidón, Rosa M. (Hospital Universitari Vall d'Hebron) ;
Mauri, Josepa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ferreira-Gonzalez, Ignacio (Hospital Universitari Vall d'Hebron)
This study aimed to evaluate the decline in urgent cardiovascular hospital admissions and in-hospital mortality during the COVID pandemic in two successive waves, and to evaluate differences by sex, age, and deprivation index subgroups. [...]
2022 - 10.3389/fcvm.2022.935850
Frontiers in Cardiovascular Medicine, Vol. 9 (april 2022)
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12 p, 4.2 MB |
Prognostic Utility of a New Risk Stratification Protocol for Secondary Prevention in Patients Attending Cardiac Rehabilitation
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Cabrera-Aguilera, Ignacio (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ivern, Consolació (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Badosa, Neus (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Marco, Ester (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Duran-Jordà, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Mojón, Diana (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vicente, Miren (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Llagostera-Martín, Marc (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Farré, Núria (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ruiz Bustillo, Sonia (Universitat Pompeu Fabra. Departament de Medicina)
Several risk scores have been used to predict risk after an acute coronary syndrome (ACS), but none of these risk scores include functional class. The aim was to assess the predictive value of risk stratification (RS), including functional class, and how cardiac rehabilitation (CR) changed RS. [...]
2022 - 10.3390/jcm11071910
Journal of clinical medicine, Vol. 11 (march 2022) , art. 1910
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11 p, 425.9 KB |
Acute Coronary Syndrome : The Risk to Young Women
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Ricci, Beatrice (University of Bologna) ;
Cenko, Edina (University of Bologna) ;
Vasiljevic, Zorana (University of Belgrade) ;
Stankovic, Goran (University of Bologna) ;
Kedev, Sasko (University "Ss. Cyril and Methodius") ;
Kalpak, Oliver (University "Ss. Cyril and Methodius") ;
Vavlukis, Marija (University "Ss. Cyril and Methodius") ;
Zdravkovic, Marija (University of Belgrade) ;
Hinic, Sasa (University of Belgrade) ;
Milicic, Davor (University of Zagreb) ;
Manfrini, Olivia (University of Bologna) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Bugiardini, Raffaele (University of Bologna) ;
Universitat Autònoma de Barcelona
Although acute coronary syndrome () mainly occurs in patients >50 years, younger patients can be affected as well. We used an age cutoff of 45 years to investigate clinical characteristics and outcomes of "young" patients with . [...]
2017 - 10.1161/JAHA.117.007519
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6 (december 2017)
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26 p, 571.2 KB |
Delayed Care and Mortality Among Women and Men With Myocardial Infarction
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Bugiardini, Raffaele (University of Bologna) ;
Ricci, Beatrice (University of Bologna) ;
Cenko, Edina (University of Bologna) ;
Vasiljevic, Zorana (University of Belgrade) ;
Kedev, Sasko (University "Ss. Cyril and Methodius") ;
Davidovic, Goran (University in Kragujevac) ;
Zdravkovic, Marija (University of Belgrade) ;
Miličić, Davor (University of Zagreb) ;
Dilic, Mirza (Clinical Center University of Sarajevo) ;
Manfrini, Olivia (University of Bologna) ;
Koller, Akos (New York Medical College) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Women with -segment-elevation myocardial infarction () have higher mortality rates than men. We investigated whether sex-related differences in timely access to care among patients may be a factor associated with excess risk of early mortality in women. [...]
2017 - 10.1161/JAHA.117.005968
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6 (august 2017)
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