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8 p, 316.8 KB |
Solid organ transplantation after hematopoietic stem cell transplantation in childhood : A multicentric retrospective survey
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Faraci, Maura (Istituto G Gaslini) ;
Bertaina, Alice (Stanford University) ;
Dalissier, Arnaud (European Society for Blood and Marrow Transplantation Pediatric Disease Working Party) ;
Ifversen, Marianne (Copenhagen University Hospital) ;
Schulz, Ansgar (University Medical Center) ;
Gennery, Andrew (Great North Children's Hospital) ;
Burkhardt, Birgit (University Hospital of Münster (Alemanya)) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Díaz de Heredia, Cristina (Vall d'Hebron Institut d'Oncologia) ;
Lanino, Edoardo (Istituto G Gaslini) ;
Lankester, Arjan C. (Leiden University Medical Center) ;
Gruhn, Bernd (Jena University Hospital (Alemania)) ;
Matthes-Martin, Susanne Medical University of Vienna ;
Kühl, Joern S. (Universitätsklinikum Leipzig) ;
Varotto, Stefania (University Hospital of Padova (Pàdua, Itàlia)) ;
Paillard, Catherine (Hôpital Hautepierre) ;
Guilmatre, Audrey (Hôpital Armand Trousseau (París, França)) ;
Sastre, Ana (Hospital Universitario La Paz (Madrid)) ;
Abecasis, Manuel (Instute Portugues Oncologia Lisboa) ;
Garwer, Birgit (University Hospital Eppendorf) ;
Sedlacek, Petr (University Hospital Motol) ;
Boelens, Jaap Jan (Memorial Sloan Kettering Cancer Center) ;
Beohou, Eric (European Society for Blood and Marrow Transplantation Pediatric Disease Working Party) ;
Bader, Peter (University Hospital of Frankfurt (Alemanya)) ;
Universitat Autònoma de Barcelona
We report data obtained from a retrospective multicenter pediatric survey on behalf of the European Society for Blood and Marrow Transplantation (EBMT). Information on solid organ transplantation (SOT) performed in pediatric recipients of either autologous or allogeneic hematopoietic stem cell transplantation (HSCT) between 1984 and 2016 was collected in 20 pediatric EBMT Centers (25. [...]
2019 -  10.1111/ajt.15240
American Journal of Transplantation, Vol. 19 Núm. 6 (june 2019) , p. 1798-1805
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10 p, 810.2 KB |
Assessment of the Plans to Optimize Antimicrobial Use in the Pediatric Population in Catalan Hospitals : The VINCat Pediatric PROA SHARP Survey
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Guarch-Ibáñez, Borja (Hospital Universitari de Girona Doctor Josep Trueta) ;
Fernández-Polo, Aurora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández Baeza, Sergi (Servei Català de la Salut) ;
Velasco-Arnaiz, Eneritz (Hospital Sant Joan de Déu (Manresa)) ;
Giménez, Montse (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sala-Castellvi, Pere (Hospital Universitari General de Catalunya) ;
Pineda, Valentí (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Melendo, Susana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
In Spain, many programs have been introduced in recent years to optimize antimicrobial stewardship in pediatric care (known as pediatric PROA). However, information on the current situation of these programs is scarce. [...]
2023 - 10.3390/antibiotics12020250
Antibiotics, Vol. 12 (january 2023)
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12 p, 659.9 KB |
Measurable Residual Disease Assessed by Flow-Cytometry Is a Stable Prognostic Factor for Pediatric T-Cell Acute Lymphoblastic Leukemia in Consecutive SEHOP Protocols Whereas the Impact of Oncogenetics Depends on Treatment
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Vega-García, N. (Institut de Recerca Sant Joan de Déu) ;
Perez-Jaume, S. (Institut de Recerca Sant Joan de Déu) ;
Esperanza-Cebollada, Elena (Institut de Recerca Sant Joan de Déu) ;
Vicente-Garcés, C. (Institut de Recerca Sant Joan de Déu) ;
Torrebadell, M. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Jiménez-Velasco, Antonio (Hospital Regional Universitario Carlos Haya (Málaga)) ;
Ortega, M. (Hospital Universitari Vall d'Hebron) ;
Llop, M. (Centro de Investigación Biomédica en Red de Cáncer) ;
Abad, Lorea (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Vagace, J.M. (Hospital Materno Infantil) ;
Minguela, A. (Instituto Murciano de Investigación Biosanitaria) ;
Pratcorona, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Sánchez-Garcia, J. (Instituto Maimónides de Investigación Biomédica de Córdoba) ;
García-Calderón, C.B. (Instituto de Biomedicina de Sevilla) ;
Gómez-Casares, M.T. (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Martín-Clavero, E. (Hospital Universitario) ;
Escudero, A. (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Riñón Martinez-Gallo, M. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Muñoz, L. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Velasco, M.R. (Haematology Department. Hospital Virgen de la Salud) ;
García-Morin, M. (Hospital General Universitario Gregorio Marañón) ;
Català, Albert (Institut de Recerca Sant Joan de Déu) ;
Pascual, A. (Hospital Regional Universitario Carlos Haya (Málaga)) ;
Velasco, P. (Hospital Universitari Vall d'Hebron) ;
Fernández, J.M. (Hospital Universitari i Politècnic La Fe (València)) ;
Lassaletta, Álvaro (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Fuster, José Luis (Instituto Murciano de Investigación Biosanitaria) ;
Badell Serra, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Molinos-Quintana, Á. (Instituto de Biomedicina de Sevilla) ;
Molinés, A. (H.U. Materno Infantil de Canarias) ;
Guerra-García, P. (Hospital Universitario La Paz (Madrid)) ;
Pérez-Martínez, Antonio (Hospital Universitario La Paz (Madrid)) ;
García-Abós, M. (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Robles Ortiz, R. (Complejo Hospitalario de Navarra) ;
Pisa, S. (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Adán, R. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Díaz de Heredia, Cristina (Hospital Universitari Vall d'Hebron) ;
Dapena, José Luis (Institut de Recerca Sant Joan de Déu) ;
Rives, S. (Institut de Recerca Sant Joan de Déu) ;
Ramírez-Orellana, M. (Hospital Infantil Universitario Niño Jesús (Madrid)) ;
Camós, Mireia (Centro de Investigación Biomédica en Red de Enfermedades Raras)
Robust and applicable risk-stratifying genetic factors at diagnosis in pediatric T-cell acute lymphoblastic leukemia (T-ALL) are still lacking, and most protocols rely on measurable residual disease (MRD) assessment. [...]
2021 - 10.3389/fped.2020.614521
Frontiers in Pediatrics, Vol. 8 (february 2021) , p. 614521
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7 p, 691.7 KB |
Loss of seryl-tRNA synthetase (SARS1) causes complex spastic paraplegia and cellular senescence
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Verdura, Edgard (Instituto de Salud Carlos III) ;
Senger, Bruno (Université de Strasbourg 1) ;
Raspall-Chaure, Miquel (Hospital Universitari Vall d'Hebron) ;
Schlüter, Agatha (Instituto de Salud Carlos III) ;
Launay, Nathalie (Instituto de Salud Carlos III) ;
Ruiz, Montserrat (Instituto de Salud Carlos III) ;
Casasnovas, Carlos (Hospital Universitari de Bellvitge) ;
Rodriguez-Palmero, Agustí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Macaya Ruiz, Alfons (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Becker, Hubert Dominique (Université de Strasbourg 1) ;
Pujol, Aurora 1968- (Institució Catalana de Recerca i Estudis Avançats)
Aminoacyl-tRNA synthetases (ARS) are key enzymes catalysing the first reactions in protein synthesis, with increasingly recognised pleiotropic roles in tumourgenesis, angiogenesis, immune response and lifespan. [...]
2022 - 10.1136/jmg-2022-108529
Journal of medical genetics, Vol. 59 (august 2022) , p. 1227-1233
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15 p, 324.4 KB |
Spontaneous reporting of adverse drug reactions in a pediatric population in a tertiary hospital
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López Valverde, Laura (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Domènech Marsal, Èlia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roguera, M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodrigo Gonzalo de Líria, Carlos (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Montané, E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The pediatric population is a vulnerable group for adverse drug reactions (ADRs), and data on spontaneous reporting of ADRs in the hospital setting are scarce. We conducted a retrospective analysis of ADRs in pediatric patients spontaneously reported by health care professionals to a Pharmacovigilance Program in a tertiary hospital between 2010 and 2020, and we compared characteristics of ADRs between pediatric age subgroups. [...]
2021 - 10.3390/jcm10235531
Journal of clinical medicine, Vol. 10 Núm. 23 (12-1 2021) , p. 5531
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23 p, 12.1 MB |
Candidate Biomarkers for the Prediction and Monitoring of Partial Remission in Pediatric Type 1 Diabetes
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Gómez Muñoz, Laia (Institut Germans Trias i Pujol) ;
Perna-Barrull, David (Institut Germans Trias i Pujol) ;
Caroz-Armayones, Josep M. (The Johns Hopkins University - Pompeu Fabra University Public Policy Center) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ;
Valls, Aina (Institut Germans Trias i Pujol) ;
Vázquez, Federico (Institut Germans Trias i Pujol) ;
Pérez Sánchez, Jacobo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corripio, Raquel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castaño, Luis (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Bel, Joan (Institut Germans Trias i Pujol) ;
Vives Pi, Marta (Institut Germans Trias i Pujol)
The partial remission (PR) phase, a period experienced by most patients with type 1 diabetes (T1D) soon after diagnosis, is characterized by low insulin requirements and improved glycemic control. Given the great potential of this phase as a therapeutic window for immunotherapies because of its association with immunoregulatory mechanisms and β-cell protection, our objective was to find peripheral immunological biomarkers for its better characterization, monitoring, and prediction. [...]
2022 - 10.3389/fimmu.2022.825426
Frontiers in immunology, Vol. 13 (february 2022)
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9 p, 611.2 KB |
Adverse Reactions to Drugs of Special Interest in a Pediatric Oncohematology Service
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Amaro-Hosey, Kristopher (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Danés Carreras, Immaculada (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vendrell Bosch, Lourdes (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alonso, Laura (Vall d'Hebron Institut d'Oncologia) ;
Renedo-Miró, Berta (Hospital Universitari Vall d'Hebron) ;
Gros, Luis (Vall d'Hebron Institut d'Oncologia) ;
Vidal Guitart, Xavier (Hospital Universitari Vall d'Hebron) ;
Cereza García, Gloria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Introduction: Drugs used in oncological diseases are frequently related to adverse drug reactions (ADR). Few studies have analyzed the toxicity of cancer treatments in children in real practice. Methods: An observational, longitudinal and prospective study has been carried out in an Oncohematology Service of a tertiary hospital. [...]
2021 - 10.3389/fphar.2021.670945
Frontiers in Pharmacology, Vol. 12 (may 2021)
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7 p, 476.9 KB |
The Importance of Rapid Influenza Testing in Pediatric Primary Care : Experience During Three Consecutive Influenza Seasons (2016-2019) in Barcelona (Catalonia, Spain)
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van Esso, Diego (Institut Català de la Salut. Servei d'Atenció Primària Muntanya) ;
Vilà, Monica (Institut Català de la Salut) ;
Andrés, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Iglesias, Sheila (Institut Català de la Salut) ;
Ferrer, Josep (Institut Català de la Salut) ;
Losada, Lucia (Institut Català de la Salut) ;
Ricos, Gemma (Institut Català de la Salut) ;
Sanchez, Lorena (Institut Català de la Salut) ;
Morera, Patricia (Institut Català de la Salut) ;
Pérez, Mar (Institut Català de la Salut) ;
Ferrandez, Mª Angeles (Institut Català de la Salut) ;
Hernando, Esther (Institut Català de la Salut) ;
Rodrigo Gonzalo de Líria, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Antón, Andrés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Clinical diagnosis of influenza has low sensitivity in infants and children. Signs and symptoms are non-specific and similar to those of other respiratory viruses. Rapid influenza diagnostic tests (RIDTs) with adequate sensitivity and specificity used at the point of care can be useful for an etiologic diagnosis of influenza in primary care. [...]
2020 - 10.3389/fped.2020.00565
Frontiers in Pediatrics, Vol. 8 (october 2020)
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