|
1.
|
|
9 p, 1.2 MB |
Bone Marrow WT1 Levels in Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplasia : Clinically Relevant Time Points and 100 Copies Threshold Value
/
Nomdedeu, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Esquirol, Albert (Institut d'Investigació Biomèdica Sant Pau) ;
Carricondo, Maite (Institut d'Investigació Biomèdica Sant Pau) ;
Pratcorona, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Hoyos Colell, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Garrido, Ana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Rubio, Miguel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bussaglia, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Estivill, Camino (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Brunet, Salut (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The outcome of allogeneic hematopoietic stem cell transplantation (HCT) in patients with myeloid malignancies is better in those without minimal residual disease (MRD) than in those with MRD+, as assessed by multiparametric flow cytometry (MPFC). [...]
2018 -  10.1016/j.bbmt.2017.09.001
Biology of blood and marrow transplantation, Vol. 24 Núm. 1 (january 2018) , p. 55-63
|
|
|
2.
|
|
12 p, 3.1 MB |
Remission outcomes in severe eosinophilic asthma with mepolizumab therapy : Analysis of the REDES study
/
Pavord, Ian (University of Oxford) ;
Gardiner, Frances (GSK House) ;
Heaney, Liam G. (Queen's University Belfast) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Price, Robert G. (Biostatistics, GSK) ;
Pullan, Alison (Plus-Project Partnership Ltd) ;
Oppenheimer, John (UMDNJ-Rutgers New Jersey Medical School) ;
Brusselle, Guy (Universitair Ziekenhuis Gent) ;
Nagase, Hiroyuki (Teikyo University School of Medicine) ;
Chupp, Geoffrey (Yale Center for Asthma and Airways Disease (YCAAD)) ;
Pizzichini, Emilio (Federal University of Santa Catarina) ;
Bañas-Conejero, David (GSK) ;
Howarth, Peter (GSK House) ;
Universitat Autònoma de Barcelona
Clinical remission as a multicomponent treatment goal in severe asthma is being explored in clinical practice. This post hoc analysis used data from the REDES study to assess the proportion of patients with severe eosinophilic asthma achieving our multicomponent definitions of clinical remission after 1 year of mepolizumab treatment. [...]
2023 - 10.3389/fimmu.2023.1150162
Frontiers in immunology, Vol. 14 (april 2023)
|
|
|
3.
|
|
27 p, 6.2 MB |
Immunoregulatory Biomarkers of the Remission Phase in Type 1 Diabetes : miR-30d-5p Modulates PD-1 Expression and Regulatory T Cell Expansion
/
Gómez Muñoz, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perna-Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Armengol, Maria Pilar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alcalde, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Català, Martí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sunye, Sergi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Valls, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez Sánchez, Jacobo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corripio, Raquel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Vives Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
The partial remission (PR) phase of type 1 diabetes (T1D) is an underexplored period characterized by endogenous insulin production and downmodulated autoimmunity. To comprehend the mechanisms behind this transitory phase and develop precision medicine strategies, biomarker discovery and patient stratification are unmet needs. [...]
2023 - 10.3390/ncrna9020017
Non-Coding RNA, Vol. 9 (february 2023)
|
|
|
4.
|
|
11 p, 3.5 MB |
Speech Illusions in People at Clinical High Risk for Psychosis Linked to Clinical Outcome
/
Hird, Emily J ;
Ohmuro, Noriyuki ;
Allen, Paul ;
Moseley, Peter ;
Kempton, Matthew J ;
Modinos, Gemma ;
Sachs, Gabriele ;
van der Gaag, Mark ;
de Haan, Lieuwe ;
Gadelha, Ary ;
Bressan, Rodrigo Affonseca ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Ruhrmann, Stephan ;
Catalan, Ana ;
McGuire, Philip
Around 20% of people at clinical high risk (CHR) for psychosis later develop a psychotic disorder, but it is difficult to predict who this will be. We assessed the incidence of hearing speech (termed speech illusions [SIs]) in noise in CHR participants and examined whether this was associated with adverse clinical outcomes. [...]
2022 - 10.1093/schbul/sbac163
Schizophrenia bulletin, Vol. 49 (december 2022) , p. 339-349
|
|
|
5.
|
|
11 p, 691.7 KB |
The Relationship Between Grey Matter Volume and Clinical and Functional Outcomes in People at Clinical High Risk for Psychosis
/
Tognin, Stefania ;
Richter, Anja ;
Kempton, Matthew J ;
Modinos, Gemma ;
Antoniades, Mathilde ;
Azis, Matilda ;
Allen, Paul ;
Bossong, Matthijs G ;
Perez, Jesus ;
Pantelis, Christos ;
Nelson, Barnaby ;
Amminger, Paul ;
Riecher-Rössler, Anita ;
Barrantes-Vidal, Neus (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ;
Krebs, Marie-Odile ;
Glenthøj, Birte ;
Ruhrmann, Stephan ;
Sachs, Gabriele ;
Rutten, Bart P. F. ;
de Haan, Lieuwe ;
van der Gaag, Mark ;
Valmaggia, Lucia ;
McGuire, Philip
To examine the association between baseline alterations in grey matter volume (GMV) and clinical and functional outcomes in people at clinical high risk (CHR) for psychosis. 265 CHR individuals and 92 healthy controls were recruited as part of a prospective multi-center study. [...]
2022 - 10.1093/schizbullopen/sgac040
Schizophrenia Bulletin Open, Vol. 3 (june 2022)
|
|
|
6.
|
|
23 p, 12.1 MB |
Candidate Biomarkers for the Prediction and Monitoring of Partial Remission in Pediatric Type 1 Diabetes
/
Gómez Muñoz, Laia (Institut Germans Trias i Pujol) ;
Perna-Barrull, David (Institut Germans Trias i Pujol) ;
Caroz-Armayones, Josep M. (The Johns Hopkins University - Pompeu Fabra University Public Policy Center) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ;
Valls, Aina (Institut Germans Trias i Pujol) ;
Vázquez, Federico (Institut Germans Trias i Pujol) ;
Pérez Sánchez, Jacobo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corripio, Raquel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castaño, Luis (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Bel, Joan (Institut Germans Trias i Pujol) ;
Vives Pi, Marta (Institut Germans Trias i Pujol)
The partial remission (PR) phase, a period experienced by most patients with type 1 diabetes (T1D) soon after diagnosis, is characterized by low insulin requirements and improved glycemic control. Given the great potential of this phase as a therapeutic window for immunotherapies because of its association with immunoregulatory mechanisms and β-cell protection, our objective was to find peripheral immunological biomarkers for its better characterization, monitoring, and prediction. [...]
2022 - 10.3389/fimmu.2022.825426
Frontiers in immunology, Vol. 13 (february 2022)
|
|
|
7.
|
|
19 p, 3.4 MB |
The Role of Premorbid IQ and Age of Onset as Useful Predictors of Clinical, Functional Outcomes, and Recovery of Individuals with a First Episode of Psychosis
/
Molina-García, Mariola (Hospital General Universitario Gregorio Marañón) ;
Fraguas, David (Hospital Clínico San Carlos (Madrid)) ;
del Rey-Mejías, Ángel (Hospital Universitario Ramón y Cajal (Madrid)) ;
Mezquida, Gisela (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Sánchez-Torres, Ana Maria (Complejo Hospitalario de Navarra) ;
Amoretti, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Lobo, Antonio (Instituto de Investigación Sanitaria de Aragón) ;
González-Pinto, Ana (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Andreu-Bernabeu, Álvaro (Hospital General Universitario Gregorio Marañón) ;
Corripio, Iluminada (Institut d'Investigació Biomèdica Sant Pau) ;
Vieta, Eduard (Universitat de Barcelona. Institut de Neurociències) ;
Baeza, Inmaculada (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Mané, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Cuesta, Manuel J. (Instituto de Investigación Sanitaria de Navarra) ;
de la Serna, Elena (Centro de Investigación Biomédica en Red de Salud Mental) ;
Payá, Beatriz (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Zorrilla, Iñaki (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Arango, Celso (Hospital General Universitario Gregorio Marañón) ;
Bernardo, Miquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Rapado-Castro, Marta (The University of Melbourne) ;
Parellada, Mara (Hospital General Universitario Gregorio Marañón) ;
Universitat Autònoma de Barcelona
Background: premorbid IQ (pIQ) and age of onset are predictors of clinical severity and long-term functioning after a first episode of psychosis. However, the additive influence of these variables on clinical, functional, and recovery rates outcomes is largely unknown. [...]
2021 - 10.3390/jcm10112474
Journal of clinical medicine, Vol. 10 (june 2021)
|
|
|
8.
|
|
14 p, 6.0 MB |
The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Trial
/
Ayala, Rosa (Centro de Investigación Biomédica en Red de Cáncer) ;
Rapado, Inmaculada (Centro de Investigación Biomédica en Red de Cáncer) ;
Onecha, Esther (Hematological Malignancies Clinical Research Unit (Madrid)) ;
Martínez-Cuadrón, David (Hospital Universitari i Politècnic La Fe (València)) ;
Carreño-Tarragona, Gonzalo (Hematological Malignancies Clinical Research Unit (Madrid)) ;
Bergua Burgues, Juan Miguel (Hospital San Pedro de Alcántara) ;
Vives Polo, Susana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Algarra Algarra, Jesus Lorenzo (Complejo Hospitalario Universitario de Albacete) ;
Tormo, Mar (Hospital Clínic Universitari (València)) ;
Martinez, Pilar (Hospital Universitario 12 de Octubre (Madrid)) ;
Serrano, Josefina (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Herrera, Pilar (Hospital Universitario Ramon y Cajal (Madrid)) ;
Ramos, Fernando (Hospital Universitario de León) ;
Salamero, Olga (Hospital Universitari Vall d'Hebron) ;
Lavilla, Esperanza (Hospital Universitario Xeral de Lugo) ;
Gil, Cristina (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
López Lorenzo, Jose Luis (Hematology Department, Fundación Jiménez Díaz (Madrid)) ;
Vidriales, María Belén (Instituto de Investigación Biomédica de Salamanca) ;
Labrador, Jorge (Hospital Universitario de Burgos) ;
Falantes, José Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Sayas, María José (Hospital Universitari Doctor Peset (València)) ;
Paiva, Bruno (Clínica Universidad de Navarra) ;
Barragán, Eva (Hospital Universitari i Politècnic La Fe (València)) ;
Prosper, Felipe (Clínica Universidad de Navarra) ;
Sanz, Miguel A.. (Hospital Universitari i Politècnic La Fe (València)) ;
Martínez-López, Joaquín (Centro de Investigación Biomédica en Red de Cáncer) ;
Montesinos, Pau (Hospital Universitari i Politècnic La Fe (València)) ;
Universitat Autònoma de Barcelona
Mutational profiling using a custom 43-gene next-generation sequencing panel revealed that patients with mutated DNMT3A or EZH2, or an increase in TET2 VAF and lower TP53 VAF showed a higher overall response. [...]
2021 - 10.3390/cancers13102458
Cancers, Vol. 13 (may 2021)
|
|
|
9.
|
|
14 p, 1.8 MB |
NK Cell Subsets Changes in Partial Remission and Early Stages of Pediatric Type 1 Diabetes
/
Gómez Muñoz, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Perna-Barrull, David (Institut Germans Trias i Pujol) ;
Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ;
Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ;
Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ;
Teniente Serra, Aina (Institut Germans Trias i Pujol) ;
Vázquez, Federico (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Murillo-Vallés, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez Sánchez, Jacobo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Corripio, Raquel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública) ;
Bel, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Vives Pi, Marta (Institut Germans Trias i Pujol)
Type 1 diabetes (T1D) is a chronic metabolic disease characterized by the autoimmune destruction of β-cells in the pancreatic islets. T1D is preceded by islet-specific inflammation led by several immune cells. [...]
2021 - 10.3389/fimmu.2020.611522
Frontiers in immunology, Vol. 11, art. 611522 (january 2021)
|
|
|
10.
|
|
10 p, 479.9 KB |
Clinical remission and subsequent relapse in patients with juvenile idiopathic arthritis : predictive factors according to therapeutic approach
/
Castillo Vilella, Mireia (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Giménez, Nuria (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Tandaipan, Jose Luis (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Quintana, Salvador ;
Modesto, Consuelo (Hospital Universitari Vall d'Hebron)
Juvenile idiopathic arthritis constitutes a significant cause of disability and quality of life impairment in pediatric and adult patients. The aim of this study was to ascertain clinical remission (CR) and subsequent relapse in juvenile idiopathic arthritis (JIA) patients, according to therapeutic approach and JIA subtype. [...]
2021 - 10.1186/s12969-021-00607-0
Pediatric rheumatology online journal, Vol. 19 (august 2021)
|
|
guest ::
email alert
or subscribe to the 
RSS feed.
