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8 p, 4.5 MB |
Peptide-based biosensing approaches for targeting breast cancer-derived exosomes
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da Fonseca Alves, Rafael (Universitat Autònoma de Barcelona. Departament de Química) ;
Pallarès-Rusiñol, Arnau (Universitat Autònoma de Barcelona. Departament de Química) ;
Rossi, Rosanna (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Martí, Mercè (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Rezende Vaz, Emilia (Universidade Estadual Paulista) ;
Gonçalves de Araújo, Thaise (Universidade Federal de Uberlândia) ;
Sotomayor, Maria (Universidade Federal de Uberlândia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
Exosomes are nanovesicles present in all the biological fluids, making them attractive as non-invasive biomarkers for diseases like cancer, among many others. However, exosomes are complex to separate and detect, requiring comprehensive molecular characterization for their routine use in diagnostics. [...]
2024 -  10.1016/j.bios.2024.116211
Biosensors & bioelectronics, Vol. 255 (July 2024) , art. 116211
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33 p, 8.1 MB |
CEBPA phase separation links transcriptional activity and 3D chromatin hubs
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Christou-Kent, Marie (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Cuartero, Sergi (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Garcia-Cabau, Carla (Institute for Research in Biomedicine (IRB Barcelona)) ;
Ruehle, Julia (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Naderi, Julian (Department of Genome Regulation. Max Planck Institute for Molecular Genetics) ;
Erber, Julia (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Neguembor, Maria Victoria (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Plana-Carmona, Marcos (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Alcoverro Bertran, Marc (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
de Andrés-Aguayo, Luisa (Centre de Regulació Genòmica) ;
Klonizakis, Antonios (Centre for Genomic Regulation (CRG). The Barcelona Institute of Science and Technology) ;
Julià Vilella, Eric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Lynch, Cian (Altos Labs. Cambridge Institute of Science) ;
Serrano, Manuel (Altos Labs. Cambridge Institute of Science) ;
Hnisz, Denes (Department of Genome Regulation. Max Planck Institute for Molecular Genetics) ;
Salvatella, Xavier (Institució Catalana de Recerca i Estudis Avançats) ;
Graf, Thomas (Universitat Pompeu Fabra) ;
Stik, Grégoire (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Cell identity is orchestrated through an interplay between transcription factor (TF) action and genome architecture. The mechanisms used by TFs to shape three-dimensional (3D) genome organization remain incompletely understood. [...]
2023 - 10.1016/j.celrep.2023.112897
Cell reports, Vol. 42 Núm. 8 (29 2023) , p. 112897
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11 p, 897.0 KB |
Insights into the light-driven hydrogen evolution reaction of mesoporous graphitic carbon nitride decorated with Pt or Ru nanoparticles
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Álvarez Prada, Luis Ignacio (Universitat Autònoma de Barcelona. Departament de Química) ;
Nguyen, Anh Dung (Technische Universität Berlin. Department of Chemistry) ;
Romero Fernández, Nuria (Universitat Autònoma de Barcelona. Departament de Química) ;
Hou, Heting (Universitat Autònoma de Barcelona. Departament de Química) ;
Benazzi, Elisabetta (Università degli Studi di Ferrara. Dipartimento di Scienze Chimiche, Farmaceutiche ed Agrarie) ;
Escriche Martínez, Lluís (Universitat Autònoma de Barcelona. Departament de Química) ;
Acharjya, Amitava (Technische Universität Berlin. Institut of Chemistry) ;
Thomas, Arne (Technische Universität Berlin. Institut of Chemistry) ;
Schwarze, Michael (Technische Universität Berlin. Department of Chemistry) ;
Schomäcker, Reinhard (Technische Universität Berlin. Department of Chemistry) ;
Sala Román, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ;
Natali, Mirco (Università degli Studi di Ferrara. Dipartimento di Scienze Chimiche, Farmaceutiche ed Agrarie) ;
García-Antón, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ;
Tasbihi, Minoo (Technische Universität Berlin. Department of Chemistry)
Ru or Pt nanoparticles have been prepared following the organometallic approach and deposited onto the surface of mesoporous graphitic carbon nitride (mpg-CN). Three different Ru-based samples have also been compared to investigate the effect of 4-phenylpyridine as a stabilizing agent. [...]
2022 - 10.1039/d1dt03006j
Dalton transactions, Vol. 51, issue 2 (January 2022) , p. 731-740
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5.
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8 p, 3.1 MB |
Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device
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Mesas Gómez, Melania (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Molina-Moya, Barbara (Institut Germans Trias i Pujol) ;
de Araújo, Bárbara Camila (Universidade Estadual Paulista. Instituto de Química) ;
Pallarès-Rusiñol, Arnau (BioEclosion S.L.) ;
Ferrer-Dalmau, Jofre (BioEclosion S.L.) ;
Boldrin Zanoni, Maria Valnice (Universidade Estadual Paulista. Instituto de Química) ;
Domínguez, José (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
This study addresses a straightforward and highly sensitive approach for detecting Mycobacterium fortuitum. The method involves a combination of filtration and direct immunomagnetic separation to isolate the bacteria retained on filters for further electrochemical magneto immunosensing in a handheld device. [...]
2024 - 10.1016/j.snb.2023.135211
Sensors and actuators. B, Chemical, Vol. 403 (March 2024) , art. 135211
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13 p, 1.4 MB |
Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters
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Mesas Gómez, Melania (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Molina-Moya, Barbara (Institut Germans Trias i Pujol) ;
de Araújo, Bárbara Camila (Universidade Estadual Paulista. Department of Analytical Chemistry) ;
Boldrin Zanoni, Maria Valnice (Universidade Estadual Paulista. Department of Analytical Chemistry) ;
Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Domínguez, José (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Pividori, María Isabel (Universitat Autònoma de Barcelona. Departament de Química)
A novel approach is presented that combines filtration and the direct immunomagnetic separation of the retained bacteria Legionella in filters, for further electrochemical immunosensing. This strategy allows for the separation and preconcentration of the water-borne pathogen from high-volume samples, up to 1000 mL. [...]
2024 - 10.1007/s00604-023-06122-1
Mikrochimica acta, Vol. 191, Issue 2 (February 2024) , art. 82
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12 p, 11.3 MB |
Influence of the surface chemistry of metal-organic polyhedra in their assembly into ultrathin films for gas separation
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Tejedor, Inés (Universidad de Zaragoza. Departamento de Química Física) ;
Andrés, Miguel A. (Instituto de Ciencia de Materiales de Aragón) ;
Carné-Sánchez, Arnau (Institut Català de Nanociència i Nanotecnologia) ;
Arjona, Mónica (Universidad de Zaragoza. Departamento de Química Física) ;
Pérez-Miana, Marta (Universidad de Zaragoza. Departamento de Ingeniería Química y Tecnologías del Medio Ambiente) ;
Sanchez-Lainez, Javier (Instituto de Nanociencia y Materiales de Aragón) ;
Coronas, Joaquin (Instituto de Nanociencia y Materiales de Aragón) ;
Fontaine, Philippe (Synchrotron SOLEIL) ;
Goldmann, Michel (Synchrotron SOLEIL) ;
Roubeau, Olivier (Instituto de Nanociencia y Materiales de Aragón) ;
Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ;
Gascón, Ignacio (Universidad de Zaragoza. Departamento de Química Física)
The formation of ultrathin films of Rh-based porous metal-organic polyhedra (Rh-MOPs) by the Langmuir-Blodgett method has been explored. Homogeneous and dense monolayer films were formed at the air-water interface either using two different coordinatively alkyl-functionalized Rh-MOPs (HRhMOP(diz)and HRhMOP(oiz)) or by in situ incorporation of aliphatic chains to the axial sites of dirhodium paddlewheels of another Rh-MOP (OHRhMOP) at the air-liquid interface. [...]
2022 - 10.1021/acsami.2c06123
ACS applied materials & interfaces, Vol. 14, issue 23 (June 2022) , p. 27495-27506
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19 p, 6.0 MB |
Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in down syndrome
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D'Acunzo, Pasquale (New York University. School of Medicine. Department of Psychiatry) ;
Pérez-González, Rocío (Institut d'Investigació Biomèdica Sant Pau) ;
Kim, Yohan (New York University. School of Medicine. Department of Psychiatry) ;
Hargash, Tal (Center for Dementia Research. Nathan S. Kline Institute for Psychiatric Research) ;
Miller, Chelsea (Center for Dementia Research. Nathan S. Kline Institute for Psychiatric Research) ;
Alldred, Melissa J. (Department of Psychiatry. New York University. School of Medicine) ;
Erdjument-Bromage, Hediye (New York University. School of Medicine. Kimmel Center for Biology and Medicine. The Skirball Institute) ;
Penikalapati, Sai Charan (Center for Dementia Research. Nathan S. Kline Institute for Psychiatric Research) ;
Pawlik, Monika (Center for Dementia Research. Nathan S. Kline Institute for Psychiatric Research) ;
Saito, Mitsuo (Division of Neurochemistry. Nathan S. Kline Institute for Psychiatric Research) ;
Saito, Mariko (New York University School of Medicine. Department of Psychiatry) ;
Ginsberg, Stephen D. (New York University. School of Medicine. Department of Neuroscience and Physiology) ;
Neubert, Thomas A. (Kimmel Center for Biology and Medicine. The Skirball Institute. New York University. School of Medicine) ;
Goulbourne, Chris N. (Center for Dementia Research. Nathan S. Kline Institute for Psychiatric Research) ;
Levy, Efrat (Department of Biochemistry and Molecular Pharmacology. New York University. School of Medicine)
Mitochondrial dysfunction is an established hallmark of aging and neurodegenerative disorders such as Down syndrome (DS) and Alzheimer's disease (AD). Using a high-resolution density gradient separation of extracellular vesicles (EVs) isolated from murine and human DS and diploid control brains, we identify and characterize a previously unknown population of double-membraned EVs containing multiple mitochondrial proteins distinct from previously described EV subtypes, including microvesicles and exosomes. [...]
2021 - 10.1126/sciadv.abe5085
Science advances, Vol. 7 Núm. 7 (december 2021) , p. eabe5085
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9.
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24 p, 2.3 MB |
Cu2ZnSnS4-Ag2S nanoscale p-n heterostructures as sensitizers for photoelectrochemical water splitting
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Yu, Xuelian (Institut de Recerca en Energia de Catalunya) ;
Liu, Jingjing (Chinese Academy of Sciences. Key Laboratory of Drinking Water Science and Technology) ;
Genç, Aziz (Institut Català de Nanociència i Nanotecnologia) ;
Ibáñez, Maria (Institut de Recerca en Energia de Catalunya) ;
Luo, Zhishan (Institut de Recerca en Energia de Catalunya) ;
Shavel, Alexey (Institut de Recerca en Energia de Catalunya) ;
Arbiol i Cobos, Jordi (Institut Català de Nanociència i Nanotecnologia) ;
Zhang, Guangjin (Chinese Academy of Sciences. Key Laboratory of Drinking Water Science and Technology) ;
Zhang, Yihe (Chinese Academy of Sciences. Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid Wastes) ;
Cabot, Andreu (Institució Catalana de Recerca i Estudis Avançats)
A cation exchange-based route was used to produce CuZnSnS (CZTS)-AgS nanoparticles with controlled composition. We report a detailed study of the formation of such CZTS-AgS nanoheterostructures and of their photocatalytic properties. [...]
2015 - 10.1021/acs.langmuir.5b02490
Langmuir, Vol. 31, issue 38 (Sep. 2015) , p. 10555-10561
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11 p, 5.3 MB |
2D/2D heterojunction of TiO2 nanoparticles and ultrathin G-C3N4 nanosheets for efficient photocatalytic hydrogen evolution
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Du, Ruifeng (Universitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica) ;
Li, Baoying (Qilu University of Technology. Shandong Provincial Key Laboratory of Molecular Engineering) ;
Han, Xu (Institut Català de Nanociència i Nanotecnologia) ;
Xiao, Ke (Universitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica) ;
Wang, Xiang (Universitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica) ;
Zhang, Chaoqi (Universitat de Barcelona. Departament d'Enginyeria Electrònica i Biomèdica) ;
Arbiol i Cobos, Jordi (Institut Català de Nanociència i Nanotecnologia) ;
Cabot, Andreu (Institució Catalana de Recerca i Estudis Avançats)
Photocatalytic hydrogen evolution is considered one of the promising routes to solve the energy and environmental crises. However, developing efficient and low-cost photocatalysts remains an unsolved challenge. [...]
2022 - 10.3390/nano12091557
Nanomaterials, Vol. 12, Issue 19 (May 2022) , art. 1557
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