2024-05-14
04:01 |
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11 p, 5.5 MB |
Gut-associated microbes are present and active in the pig nasal cavity
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Obregon-Gutierrez, Pau (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Bonillo-Lopez, Laura (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Correa-Fiz, Florencia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Sibila, Marina (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Kochanowski, Karl (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Aragon, Virginia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
The nasal microbiota is a key contributor to animal health, and characterizing the nasal microbiota composition is an important step towards elucidating the role of its different members. Efforts to characterize the nasal microbiota composition of domestic pigs and other farm animals frequently report the presence of bacteria that are typically found in the gut, including many anaerobes from the Bacteroidales and Clostridiales orders. [...]
2024 -  10.1038/s41598-024-58681-9
Scientific reports, Vol. 14 (april 2024)
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2024-05-14
04:01 |
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14 p, 8.2 MB |
Development of a new loop-mediated isothermal amplification test for the sensitive, rapid, and economic detection of different genotypes of Classical swine fever virus
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Bohórquez, Jose Alejandro (University of Illinois at Urbana-Champaign. Veterinary Diagnostic Laboratory) ;
Muñoz-Aguilera, Adriana (Instituto Colombiano Agropecuario (ICA)) ;
Lanka, Saraswathi (University of Illinois at Urbana-Champaign. Veterinary Diagnostic Laboratory) ;
Coronado, Liani (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Rosell, Rosa (Generalitat de Catalunya. Departament d'Acció Climàtica, Alimentació i Agenda Rural) ;
Alberch, Mònica (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Maddox, Carol W. (University of Illinois at Urbana-Champaign. Department of Pathobiology) ;
Ganges, Llilianne (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Classical swine fever virus (CSFV) remains one of the most important pathogens in animal health. Pathogen detection relies on viral RNA extraction followed by RT-qPCR. Novel technologies are required to improve diagnosis at the point of care. [...]
2024 - 10.3389/fcimb.2024.1372166
Frontiers in cellular and infection microbiology, Vol. 14 (april 2024)
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2024-04-19
04:26 |
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18 p, 2.2 MB |
Immunization with V987H-stabilized Spike glycoprotein protects K18-hACE2 mice and golden Syrian hamsters upon SARS-CoV-2 infection
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Avila-Nieto, Carlos (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Vergara-Alert, Júlia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Amengual-Rigo, Pep (Barcelona Supercomputing Center) ;
Ainsua-Enrich, Erola (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brustolin, Marco (Institute of Tropical Medicine. Present Address: Department of Biomedical Sciences) ;
Rodríguez de la Concepción, María Luisa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pedreño-López, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rodon, Jordi (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pradenas, Edwards (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Marfil, Sílvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ballana, Ester (Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pérez, Mònica (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Roca, Núria (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Tarrés-Freixas, Ferran (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Cantero, Guillermo (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Pons-Grífols, Anna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rovirosa, Carla (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Aguilar-Gurrieri, Carmen (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ortiz, Raquel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Barajas Vélez, Ana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Trinité, Benjamin (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Lepore, Rosalba (Barcelona Supercomputing Center) ;
Muñoz-Basagoiti, Jordana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Perez-Zsolt, Daniel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Izquierdo Useros, Nuria (Centro de Investigación Biomédica en Red de Enfermedades Infecciosas) ;
Valencia, Alfonso (Universitat de Vic - Central de Catalunya) ;
Blanco, Julià (Universitat de Vic - Central de Catalunya) ;
Guallar, Victor (Institució Catalana de Recerca i Estudis Avançats) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Carrillo, Jorge (Centro de Investigación Biomédica en Red de Enfermedades Infecciosas)
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are crucial to fight against the coronavirus disease 2019 pandemic. Most vaccines are based on a mutated version of the Spike glycoprotein [K986P/V987P (S-2P)] with improved stability, yield and immunogenicity. [...]
2024 - 10.1038/s41467-024-46714-w
Nature communications, Vol. 15 (march 2024)
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2024-04-09
04:01 |
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15 p, 1.4 MB |
High-Fat Diet-Induced Obesity Increases Brain Mitochondrial Complex I and Lipoxidation-Derived Protein Damage
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Berdún, Rebeca (Institut de Recerca Biomèdica de Lleida) ;
Obis, Èlia (Institut de Recerca Biomèdica de Lleida) ;
Mota-Martorell, Natàlia (Institut de Recerca Biomèdica de Lleida) ;
Bassols Teixidó, Anna Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Valent, Daniel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Serrano, José C. E. (Institut de Recerca Biomèdica de Lleida) ;
Martín-Garí, Meritxell (Institut de Recerca Biomèdica de Lleida) ;
Rodríguez-Palmero, María (Laboratorios Ordesa S.L.) ;
Moreno-Muñoz, José Antonio (Laboratorios Ordesa S.L.) ;
Tibau, Joan (Institut de Recerca i Tecnologia Agroalimentàries) ;
Quintanilla, Raquel (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Pamplona, Reinald (Institut de Recerca Biomèdica de Lleida) ;
Portero-Otín, Manuel (Institut de Recerca Biomèdica de Lleida) ;
Jové, Mariona (Institut de Recerca Biomèdica de Lleida)
Obesity is a risk factor for highly prevalent age-related neurodegenerative diseases, the pathogenesis of whichinvolves mitochondrial dysfunction and protein oxidative damage. Lipoxidation, driven by high levels of peroxidizable unsaturated fatty acids and low antioxidant protection of the brain, stands out as a significant risk factor. [...]
2024 - 10.3390/antiox13020161
Antioxidants, Vol. 13 (january 2024)
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2024-03-20
04:05 |
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16 p, 4.2 MB |
Nanoparticle-Based Secretory Granules Induce a Specific and Long-Lasting Immune Response through Prolonged Antigen Release
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Bosch Camós, Laia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Martínez-Torró, Carlos (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
López-Laguna, Hèctor (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Lascorz Lozano, Jara A (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Argilaguet, Jordi 1977- (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Rodriguez, Fernando (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Developing prolonged antigen delivery systems that mimic long-term exposure to pathogens appears as a promising but still poorly explored approach to reach durable immunities. In this study, we have used a simple technology by which His-tagged proteins can be assembled, assisted by divalent cations, as supramolecular complexes with progressive complexity, namely protein-only nanoparticles and microparticles. [...]
2024 - 10.3390/nano14050435
Nanomaterials, Vol. 14, Issue 5 (February 2024) , art. 435
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2024-03-01
04:52 |
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11 p, 3.5 MB |
The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs
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Murray, Gemma G. R. (University of Cambridge. Department of Veterinary Medicine) ;
Hossain, A. S. Md. Mukarram (Cancer Research UK Manchester Institute) ;
Miller, Eric L. (Haverford College. Department of Biology) ;
Bruchmann, Sebastian (University of Cambridge. Department of Veterinary Medicine) ;
Balmer, Andrew J. (University of Cambridge. Department of Veterinary Medicine) ;
Matuszewska, Marta (University of Cambridge. Department of Veterinary Medicine) ;
Herbert, Josephine (University of Portsmouth. Centre for Enzyme Innovation) ;
Hadjirin, Nazreen F. (University of Oxford. Nuffield Department of Population Health) ;
Mugabi, Robert (Iowa State University. College of Veterinary Medicine) ;
Li, Ganwu (Iowa State University. College of Veterinary Medicine) ;
Ferrando, Maria Laura (Wageningen University. Animal Sciences Department) ;
Fernandes de Oliveira, Isabela Maria (Wageningen University. Animal Sciences Department) ;
Nguyen, Thanh (Oxford University Clinical Research Unit) ;
Yen, Phung L. K. (Oxford University Clinical Research Unit) ;
Phuc, Ho D. (Oxford University Clinical Research Unit) ;
Zaw Moe, Aung (Livestock Breeding and Veterinary Department) ;
Su Wai, Thiri (Livestock Breeding and Veterinary Department) ;
Gottschalk, Marcelo (University of Montreal) ;
Aragon, Virginia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Valentin-Weigand, Peter (University of Veterinary Medicine Hannover. Institute for Microbiology) ;
Heegaard, Peter M. H. (Technical University of Denmark. Department of Health Technology) ;
Vrieling, Manouk (Wageningen Bioveterinary Research) ;
Thein Maw, Min (Livestock Breeding and Veterinary Department) ;
Thidar Myint, Hnin (Livestock Breeding and Veterinary Department) ;
Tun Win, Ye (Livestock Breeding and Veterinary Department) ;
Thi Hoa, Ngo (Ngoc Thach University of Medicine. Microbiology Department and Center for Tropical Medicine Research) ;
Bentley, Stephen D. (Wellcome Sanger Institute. Parasites and Microbes Programme) ;
Clavijo, Maria J. (Iowa State University. College of Veterinary Medicine) ;
Wells, Jerry M. (Wageningen University. Animal Sciences Department) ;
Tucker, Alexander W. (University of Cambridge. Department of Veterinary Medicine) ;
Weinert, Lucy A. (University of Cambridge. Department of Veterinary Medicine)
There is growing concern that rapid growth in livestock production and major changes in farming practices are driving the emergence of pathogens capable of causing disease in both livestock and humans. [...]
2023 - 10.1073/pnas.2307773120
Proceedings of the National Academy of Sciences of the United States of America, Vol. 120 (november 2023)
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2024-03-01
04:52 |
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14 p, 4.7 MB |
Safety and Efficacy upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued Virus
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Moreno, Sandra (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Lorenzo, Gema (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
López-Valiñas, Álvaro (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
de la Losa, Nuria (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Alonso, Celia (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Charro, Elena (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Núñez, J. Ignacio (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Sánchez-Cordón, Pedro J. (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Borrego, Belén (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal) ;
Brun, Alejandro (Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria. Centro de Investigación en Sanidad Animal)
The introduction of three single nucleotide mutations into the genome of the virulent RVFV ZH548 strain allows for the rescue of a fully attenuated virus in mice (ZH548-rA2). These mutations are located in the viral genes encoding the RdRp and the non-structural protein NSs. [...]
2024 - 10.3390/v16010087
Viruses, Vol. 16 (january 2024)
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2024-03-01
04:52 |
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14 p, 3.1 MB |
Clinical, Pathological and Virological Outcomes of Tissue-Homogenate-Derived and Cell-Adapted Strains of Porcine Epidemic Diarrhea Virus (PEDV) in a Neonatal Pig Model
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López-Figueroa, Carlos (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Cano, Esmeralda (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Navarro, Núria (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Pérez-Maíllo, Mónica (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pujols, Joan (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Núñez, J. Ignacio (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Vergara-Alert, Júlia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Porcine epidemic diarrhea virus (PEDV) is characterized by diarrhea, vomiting, dehydration, and high mortality rates in neonatal piglets. Two distinct genogroups, S-INDEL (G1a, G1b) and non-S INDEL (G2a, G2b, and G2c), circulate worldwide and are characterized by varying degrees of virulence. [...]
2023 - 10.3390/v16010044
Viruses, Vol. 16 (december 2023)
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2024-03-01
04:52 |
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10 p, 4.1 MB |
2023 International African Swine Fever Workshop : Critical Issues That Need to Be Addressed for ASF Control
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Wang, Lihua (Kansas State University. Center on Vaccine Evaluation and Alternatives for Antimicrobials) ;
Ganges, Llilianne (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Dixon, Linda K. (The Pirbright Institute (Regne Unit)) ;
Bu, Zhigao (Chinese Academy of Agricultural Sciences) ;
Zhao, Dongming (Chinese Academy of Agricultural Sciences) ;
Truong, Quang Lam (Vietnam National University of Agriculture) ;
Richt, Juergen A. (Kansas State University) ;
Jin, Meilin (Huazhong Agricultural University) ;
Netherton, Christopher L. (The Pirbright Institute (Regne Unit)) ;
Benarafa, Charaf (University of Bern) ;
Summerfield, Artur (University of Bern) ;
Weng, Changjiang (Chinese Academy of Agricultural Sciences) ;
Peng, Guiqing (Huazhong Agricultural University) ;
Reis, Ana L. (The Pirbright Institute (Regne Unit)) ;
Han, Jun (China Agricultural University) ;
Penrith, Mary-Louise (University of Pretoria) ;
Mo, Yupeng (Dekang Agriculture and Animal Husbandry Group) ;
Su, Zhipeng (Liyuan Group) ;
Vu Hoang, Dang (National Institute of Veterinary Research) ;
Pogranichniy, Roman M. (Kansas State University) ;
Balaban-Oglan, David-Adrian (University of Agronomic Science and Veterinary Medicine of Bucharest) ;
Li, Yuzhen (Kansas State University) ;
Wang, Kewen (Zoetis China) ;
Cai, Xuepeng (Chinese Veterinary Drug Association) ;
Shi, Jishu (Kansas State University)
The 2023 International African Swine Fever Workshop (IASFW) took place in Beijing, China, on 18-20 September 2023. It was jointly organized by the U. S. -China Center for Animal Health (USCCAH) at Kansas State University (KSU) and the Chinese Veterinary Drug Association (CVDA) and sponsored by the United States Department of Agriculture Foreign Agricultural Service (USDA-FAS), Harbin Veterinary Research Institute, and Zoetis Inc. [...]
2023 - 10.3390/v16010004
Viruses, Vol. 16 (december 2023)
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2024-03-01
04:52 |
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26 p, 1021.9 KB |
Potential business model for a European vaccine R&D infrastructure and its estimated socio-economic impact
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Jungbluth, Stefan (European Vaccine Initiative) ;
Martin, William (European Vaccine Initiative) ;
Slezak, Monika (European Vaccine Initiative) ;
Depraetere, Hilde (European Vaccine Initiative) ;
Guzman, Carlos A. (Helmholtz Centre for Infection Research) ;
Ussi, Anton (EATRIS- European Research Infrastructure for Translational Medicine) ;
Morrow, David (EATRIS- European Research Infrastructure for Translational Medicine) ;
Van Heuverswyn, Fran (Flanders Vaccine) ;
Arnouts, Sven (Ghent University) ;
Carrondo, Manuel J. T. (Instituto de Biologia Experimental e Tecnológica) ;
Olesen, Ole (European Vaccine Initiative) ;
Ottenhoff, Tom H.M. (Leiden University Medical Center) ;
Dockrell, H. M. (London School of Hygiene & Tropical Medicine) ;
Ho, Mei Mei (Medicines and Healthcare products Regulatory Agency) ;
Dobly, Alexandre (Sciensano) ;
Christensen, Dennis (Statens Serum Institut) ;
Segalés Coma, Joaquim (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Laurent, Fabrice (Université François Rabelais de Tours) ;
Lantier, Frédéric (Université François Rabelais de Tours) ;
Stockhofe-Zurwieden, Norbert (Wageningen Bioveterinary Research) ;
Morelli, Francesca (CIRMMP) ;
Langermans, Jan A.M. (Biomedical Primate Research Centre) ;
Verreck, Frank A.W. (Biomedical Primate Research Centre) ;
Le Grand, Roger (Université Paris-Saclay) ;
Sloots, Arjen (Intravacc) ;
Medaglini, Donata (University of Siena) ;
Lawrenz, Maria (Vaccine Formulation Institute) ;
Collin, Nicolas (Vaccine Formulation Institute)
Research infrastructures are facilities or resources that have proven fundamental for supporting scientific research and innovation. However, they are also known to be very expensive in their establishment, operation and maintenance. [...]
2023 - 10.12688/f1000research.141399.1
F1000Research, Vol. 12 (october 2023)
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