Rmst is a novel marker for the mouse ventral mesencephalic floor plate and the anterior dorsal midline cells
Uhde, Christopher W. (Imperial College London. MRC Clinical Sciences Centre)
Vives Armengol, Joaquim (Imperial College London. MRC Clinical Sciences Centre)
Jaeger, Ines (Imperial College London. MRC Clinical Sciences Centre)
Li, Meng (Imperial College London. MRC Clinical Sciences Centre)

Fecha:	2010
Resumen:	The availability of specific markers expressed in different regions of the developing nervous system provides a useful tool to illuminate their development, regulation and function. We have identified by expression profiling a putative non-coding RNA, Rmst, that exhibits prominent expression in the midbrain floor plate region, the isthmus and the roof plate of the anterior neural tube. At the developmental stage when the ventral dopaminergic neuron territory is being established, Rmst expression appears to be restricted to the presumptive dopaminergic neurons of the ventral tegmental area that lies close to the ventral midline. Thus this study presents Rmst as a novel marker for the developing dopaminergic neurons in the mesencephalic floor plate as well as a marker for the dorsal midline cells of the anterior neural tube and the isthmic organizer.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; Versió publicada
Materia:	Sistema nerviós ; Neurologia
Publicado en:	PloS one, Vol. 5, Issue 1 (January 2010) , p. e8641, ISSN 1932-6203

DOI: 10.1371/journal.pone.0008641
PMID: 20062813

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