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Using non-invasive brain stimulation to augment motor training-induced plasticity
Bolognini, Nadia (Harvard Medical School (Boston, Estats Units d'Amèrica))
Pascual Leone, Álvaro (Universitat Autònoma de Barcelona)
Fregni, Felipe (Harvard Medical School (Boston, Estats Units d'Amèrica))

Date: 2009
Abstract: Therapies for motor recovery after stroke or traumatic brain injury are still not satisfactory. To date the best approach seems to be the intensive physical therapy. However the results are limited and functional gains are often minimal. The goal of motor training is to minimize functional disability and optimize functional motor recovery. This is thought to be achieved by modulation of plastic changes in the brain. Therefore, adjunct interventions that can augment the response of the motor system to the behavioural training might be useful to enhance the therapy-induced recovery in neurological populations. In this context, noninvasive brain stimulation appears to be an interesting option as an add-on intervention to standard physical therapies. Two non-invasive methods of inducing electrical currents into the brain have proved to be promising for inducing long-lasting plastic changes in motor systems: transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). These techniques represent powerful methods for priming cortical excitability for a subsequent motor task, demand, or stimulation. Thus, their mutual use can optimize the plastic changes induced by motor practice, leading to more remarkable and outlasting clinical gains in rehabilitation. In this review we discuss how these techniques can enhance the effects of a behavioural intervention and the clinical evidence to date.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: article ; recerca ; publishedVersion
Published in: Journal of neuroengineering and rehabilitation, Vol. 6, N. 8 (March 2009) , p. 1-13, ISSN 1743-0003

DOI: 10.1186/1743-0003-6-8
PMID: 19292910


13 p, 368.4 KB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2013-11-29, last modified 2020-11-07



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